Generic name: Mafenide Solution (MA fe nide)
Brand name: Sulfamylon
Drug class: Topical antibiotics
Medically reviewed by Drugs.com. Last updated on Dec 5, 2020.
Uses of Mafenide Solution:
- It is used to avoid or treat skin infections in patients with burns.
What do I need to tell my doctor BEFORE I take Mafenide Solution?
- If you have an allergy to mafenide or any other part of mafenide solution.
- If you are allergic to mafenide solution; any part of mafenide solution; or any other drugs, foods, or substances. Tell your doctor about the allergy and what signs you had.
- If you are breast-feeding or plan to breast-feed.
This medicine may interact with other drugs or health problems.
Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take mafenide solution with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.
What are some things I need to know or do while I take Mafenide Solution?
- Tell all of your health care providers that you take mafenide solution. This includes your doctors, nurses, pharmacists, and dentists.
- Be careful if you have G6PD deficiency. Anemia may happen.
- Tell your doctor if you are pregnant or plan on getting pregnant. You will need to talk about the benefits and risks of using mafenide solution while you are pregnant.
How is this medicine (Mafenide Solution) best taken?
Use mafenide solution as ordered by your doctor. Read all information given to you. Follow all instructions closely.
- Do not take mafenide solution by mouth. Use on your skin only. Keep out of your mouth, nose, and eyes (may burn).
- Use as you have been told, even if your signs get better.
- Wash your hands before and after use. Do not wash your hands after use if putting this on your hand.
- Mix powder with sterile water or sodium chloride until it dissolves.
- Put liquid on the gauze covering the burn.
What do I do if I miss a dose?
- Put on a missed dose as soon as you think about it.
- If it is close to the time for your next dose, skip the missed dose and go back to your normal time.
- Do not put on 2 doses or extra doses.
What are some side effects that I need to call my doctor about right away?
WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:
- Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
- Signs of too much acid in the blood (acidosis) like confusion; fast breathing; fast heartbeat; a heartbeat that does not feel normal; very bad stomach pain, upset stomach, or throwing up; feeling very sleepy; shortness of breath; or feeling very tired or weak.
- Very bad irritation where mafenide solution is used.
- A very bad and sometimes deadly type of anemia called hemolytic anemia has happened with mafenide solution. Call your doctor right away if you have pale skin, dizziness, fever or chills, very bad back or belly pain, dark urine, yellow skin or eyes, or you feel very tired or weak.
What are some other side effects of Mafenide Solution?
All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:
- Short-term pain after use.
- Irritation where mafenide solution is used.
These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.
You may report side effects to the FDA at 1-800-332-1088. You may also report side effects at https://www.fda.gov/medwatch.
If OVERDOSE is suspected:
If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
How do I store and/or throw out Mafenide Solution?
- Store at room temperature.
- Protect from heat.
- Store in a dry place. Do not store in a bathroom.
- Store liquid in a closed container.
- Throw away any part of the unopened liquid container not used after 28 days.
- Throw away any part of the opened liquid container not used after 48 hours.
- Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
- Throw away unused or expired drugs. Do not flush down a toilet or pour down a drain unless you are told to do so. Check with your pharmacist if you have questions about the best way to throw out drugs. There may be drug take-back programs in your area.
Consumer information use
- If your symptoms or health problems do not get better or if they become worse, call your doctor.
- Do not share your drugs with others and do not take anyone else's drugs.
- Some drugs may have another patient information leaflet. Check with your pharmacist. If you have any questions about mafenide solution, please talk with your doctor, nurse, pharmacist, or other health care provider.
- If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
More about mafenide topical
- Side Effects
- During Pregnancy
- Dosage Information
- Pricing & Coupons
- En Español
- Drug class: topical antibiotics
- Other brands
Related treatment guides
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.