Generic Name: pregabalin (pre-GAB-a-lin)
Brand Name: Lyrica
Lyrica is used for:
Treating fibromyalgia or nerve pain caused by certain conditions (eg, shingles, diabetic nerve problems, spinal cord injury). It is also used in combination with other medicines to treat certain types of seizures. It may also be used for other conditions as determined by your doctor.
Lyrica is an anticonvulsant and neuropathic pain agent. Exactly how Lyrica works is not known. It is thought to bind to certain areas in the brain that help reduce seizures, nerve pain, and anxiety.
Do NOT use Lyrica if:
- you are allergic to any ingredient in Lyrica
Contact your doctor or health care provider right away if any of these apply to you.
Before using Lyrica:
Some medical conditions may interact with Lyrica. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
- if you are pregnant, planning to become pregnant, or are breast-feeding
- if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
- if you have allergies to medicines, foods, or other substances
- if you have heart problems (eg, congestive heart failure, irregular heartbeat), high blood pressure, muscle problems, diabetes, or bleeding problems or low platelets
- if you have kidney problems or are on dialysis
- if you have a history of mental or mood problems (eg, depression), suicidal thoughts or attempts, or alcohol or drug abuse
- if you have a history of angioedema (swelling of the hands, face, lips, eyes, throat, or tongue; difficulty swallowing or breathing; or unusual hoarseness)
- if you plan to father a child
Some MEDICINES MAY INTERACT with Lyrica. Tell your health care provider if you are taking any other medicines, especially any of the following:
- Angiotensin-converting enzyme (ACE) inhibitors (eg, enalapril) because the risk of angioedema may be increased
- Benzodiazepines (eg, lorazepam) or narcotic pain medicines (eg, oxycodone) because the risk of drowsiness may be increased
- Thiazolidinedione antidiabetic agents (eg, rosiglitazone) because the risk of weight gain or swelling of the hands and feet may be increased
This may not be a complete list of all interactions that may occur. Ask your health care provider if Lyrica may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.
How to use Lyrica:
Use Lyrica as directed by your doctor. Check the label on the medicine for exact dosing instructions.
- Lyrica comes with an extra patient information sheet called a Medication Guide. Read it carefully. Read it again each time you get Lyrica refilled.
- Take Lyrica by mouth with or without food.
- Take Lyrica on a regular schedule to get the most benefit from it.
- Taking Lyrica at the same time each day will help you remember to take it.
- If you miss a dose of Lyrica, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.
Ask your health care provider any questions you may have about how to use Lyrica.
Important safety information:
- Lyrica may cause drowsiness, dizziness, blurred vision, or light-headedness. These effects may be worse if you take it with alcohol or certain medicines. Use Lyrica with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
- Do not drink alcohol while you are taking Lyrica.
- Check with your doctor before you use medicines that may cause drowsiness (eg, sleep aids, muscle relaxers) while you are taking Lyrica; it may add to their effects. Ask your pharmacist if you have questions about which medicines may cause drowsiness.
- Lyrica may reduce the number of clot-forming cells (platelets) in your blood. Avoid activities that may cause bruising or injury. Tell your doctor if you have unusual bruising or bleeding. Tell your doctor if you have dark, tarry, or bloody stools.
- Do NOT take more than the recommended dose or use for longer than prescribed without checking with your doctor.
- Do not suddenly stop taking Lyrica or change your dose without checking with your doctor. If you stop taking Lyrica suddenly, you may have headaches, nausea, diarrhea, trouble sleeping, anxiety, or increased sweating. If you have epilepsy and you stop taking Lyrica suddenly, you may have seizures more often. If you need to stop taking Lyrica, your dose should be gradually reduced over a period of at least 1 week.
- If you stop taking Lyrica for any reason, contact your doctor right away. Do not start taking it again unless your doctor tells you to. Discuss any questions or concerns with your doctor.
- If you develop new or worsening seizures, contact your doctor right away.
- Patients who take Lyrica may be at increased risk of suicidal thoughts or actions. The risk may be greater in patients who have had suicidal thoughts or actions in the past. Watch patients who take Lyrica closely. Contact the doctor at once if new, worsened, or sudden symptoms (eg, depressed mood; anxious, restless, or irritable behavior; panic attacks; or any unusual change in mood or behavior) occur. Contact the doctor right away if any signs of suicidal thoughts or actions occur.
- Tell your doctor or dentist that you take Lyrica before you receive any medical or dental care, emergency care, or surgery.
- Diabetes patients - Monitor your skin closely for any new or unusual sores while you take Lyrica.
- In animal studies, birth defects were seen in the babies of male animals who were treated with Lyrica. It is not known if this may also occur in humans. If you are planning to father a child, discuss the possible risks with your doctor.
- Use Lyrica with caution in the ELDERLY; they may be more sensitive to its effects.
- Lyrica should be used with extreme caution in CHILDREN; safety and effectiveness in children have not been confirmed.
- PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Lyrica while you are pregnant. It is not known if this medicine is found in breast milk. Do not breast-feed while taking Lyrica.
Possible side effects of Lyrica:
All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:
Seek medical attention right away if any of these SEVERE side effects occur:
Blurred vision; changes in sexual function; constipation; dizziness; drowsiness; dry mouth; headache; increased appetite; light-headedness; tiredness; trouble concentrating; weakness; weight gain.
Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, throat, or tongue; unusual hoarseness); burning, numbness, or tingling; chest pain; confusion; fast or irregular heartbeat; fever, chills, or persistent sore throat; inability to control urination; loss of coordination; memory loss; muscle aches, pain, tenderness, or weakness (especially if this occurs with a fever or general feeling or discomfort); new or unusual skin sores; new or worsening mental or mood changes (eg, anxiety, depression, restlessness, irritability, panic attacks, feeling "high," behavior changes, suicidal thoughts or attempts); new or worsening seizures; reddened, blistered, swollen, or peeling skin; shortness of breath or wheezing; speaking problems; sudden, unexplained weight gain; swelling of the hands, feet, or ankles; tremor; trouble sleeping; trouble walking; unusual bruising or bleeding; severe or persistent tiredness or weakness; vision changes.
This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.
If OVERDOSE is suspected:
Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately.Proper storage of Lyrica:
Store Lyrica at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Lyrica out of the reach of children and away from pets.
- If you have any questions about Lyrica, please talk with your doctor, pharmacist, or other health care provider.
- Lyrica is to be used only by the patient for whom it is prescribed. Do not share it with other people.
- If your symptoms do not improve or if they become worse, check with your doctor.
- Check with your pharmacist about how to dispose of unused medicine.
This information should not be used to decide whether or not to take Lyrica or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about Lyrica. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to Lyrica. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using Lyrica.
Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.
More about Lyrica (pregabalin)
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- Drug class: gamma-aminobutyric acid analogs