Medically reviewed by Drugs.com. Last updated on Apr 14, 2022.
- There is a higher chance of death in older adults who take loxapine inhalation powder for mental problems caused by dementia. Most of the deaths were linked to heart disease or infection. This medicine is not approved to treat mental problems caused by dementia.
- This medicine can cause you to have very bad breathing problems or to stop breathing. This medicine will be given to you in a hospital or doctor's office. You will be closely watched. Do not use loxapine inhalation powder if you have ever had lung or breathing problems like asthma or COPD (chronic obstructive pulmonary disease). Tell your doctor right away if you have wheezing, coughing, chest tightness, or shortness of breath.
Uses of Loxapine Inhalation Powder:
- It is used to treat schizophrenia.
- It is used to treat bipolar problems.
- It may be given to you for other reasons. Talk with the doctor.
What do I need to tell my doctor BEFORE I take Loxapine Inhalation Powder?
- If you have an allergy to loxapine or any other part of loxapine inhalation powder.
- If you are allergic to loxapine inhalation powder; any part of loxapine inhalation powder; or any other drugs, foods, or substances. Tell your doctor about the allergy and what signs you had.
- If you are very sleepy.
- If you have recently drunk a lot of alcohol or taken a big amount of drugs that may slow your actions like phenobarbital or some pain drugs like oxycodone.
- If you have trouble breathing.
- If you are taking any drugs to treat lung or breathing problems like asthma or COPD.
This is not a list of all drugs or health problems that interact with loxapine inhalation powder.
Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take loxapine inhalation powder with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.
What are some things I need to know or do while I take Loxapine Inhalation Powder?
- Tell all of your health care providers that you take loxapine inhalation powder. This includes your doctors, nurses, pharmacists, and dentists.
- Avoid driving and doing other tasks or actions that call for you to be alert until you see how loxapine inhalation powder affects you.
- To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down. Be careful going up and down stairs.
- Avoid drinking alcohol while taking loxapine inhalation powder.
- Talk with your doctor before you use other drugs and natural products that slow your actions.
- Have blood work checked as you have been told by the doctor. Talk with the doctor.
- Low white blood cell counts have happened with drugs like this one. This may lead to a higher chance of infection. Rarely, infections have been deadly. Tell your doctor if you have ever had a low white blood cell count. Call your doctor right away if you have signs of infection like fever, chills, or sore throat.
- Be careful in hot weather or while being active. Drink lots of fluids to stop fluid loss.
- Have an eye exam as you have been told by your doctor.
- Dizziness, sleepiness, and feeling less stable may happen with loxapine inhalation powder. These may lead to falling, which can cause broken bones or other health problems.
- Older adults with dementia taking drugs like this one have had a higher number of strokes. Sometimes these have been deadly. This medicine is not approved to treat mental problems caused by dementia.
- If you are 65 or older, use loxapine inhalation powder with care. You could have more side effects.
- Tell your doctor if you are pregnant or plan on getting pregnant. You will need to talk about the benefits and risks of using loxapine inhalation powder while you are pregnant.
- Taking loxapine inhalation powder in the third trimester of pregnancy may lead to uncontrolled muscle movements and withdrawal in the newborn.
- Tell your doctor if you are breast-feeding. You will need to talk about any risks to your baby.
How is this medicine (Loxapine Inhalation Powder) best taken?
Use loxapine inhalation powder as ordered by your doctor. Read all information given to you. Follow all instructions closely.
- For breathing in only.
- You will be shown how to use loxapine inhalation powder right before you take it.
What do I do if I miss a dose?
- Call your doctor to find out what to do.
What are some side effects that I need to call my doctor about right away?
WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:
- Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
- Trouble controlling body movements, twitching, change in balance, trouble swallowing or speaking.
- Shakiness, trouble moving around, or stiffness.
- Very bad dizziness or passing out.
- A fast heartbeat.
- Very bad headache.
- Feeling confused.
- Change in eyesight, eye pain, or very bad eye irritation.
- Trouble passing urine.
- Slurred speech.
- Feeling very tired or weak.
- Any unexplained bruising or bleeding.
- Enlarged breasts.
- Nipple discharge.
- Not able to get or keep an erection.
- For women, no period.
- A very bad and sometimes deadly health problem called neuroleptic malignant syndrome (NMS) may happen. Call your doctor right away if you have any fever, muscle cramps or stiffness, dizziness, very bad headache, confusion, change in thinking, fast heartbeat, heartbeat that does not feel normal, or are sweating a lot.
- Some people may get a severe muscle problem called tardive dyskinesia. This problem may lessen or go away after stopping loxapine inhalation powder, but it may not go away. The risk is greater with diabetes and in older adults, especially older women. The risk is greater with longer use or higher doses, but it may also occur after short-term use with low doses. Call your doctor right away if you have trouble controlling body movements or problems with your tongue, face, mouth, or jaw like tongue sticking out, puffing cheeks, mouth puckering, or chewing.
What are some other side effects of Loxapine Inhalation Powder?
All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:
- Feeling sleepy.
- Trouble sleeping.
- Dry mouth.
- Change in taste.
- Throat irritation.
These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.
You may report side effects to the FDA at 1-800-332-1088. You may also report side effects at https://www.fda.gov/medwatch.
If OVERDOSE is suspected:
If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
How do I store and/or throw out Loxapine Inhalation Powder?
- If you need to store loxapine inhalation powder at home, talk with your doctor, nurse, or pharmacist about how to store it.
Consumer information use
- If your symptoms or health problems do not get better or if they become worse, call your doctor.
- Do not share your drugs with others and do not take anyone else's drugs.
- Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
- Throw away unused or expired drugs. Do not flush down a toilet or pour down a drain unless you are told to do so. Check with your pharmacist if you have questions about the best way to throw out drugs. There may be drug take-back programs in your area.
- This medicine comes with an extra patient fact sheet called a Medication Guide. Read it with care. Read it again each time loxapine inhalation powder is refilled. If you have any questions about loxapine inhalation powder, please talk with the doctor, pharmacist, or other health care provider.
- If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
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- During pregnancy or Breastfeeding
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