Lialda delayed-release tabletsPronunciation
Generic Name: mesalamine (me-SAL-a-meen)
Brand Name: Examples include Asacol and Lialda
Lialda delayed-release tablets are used for:
Treating and maintaining remission of various forms of mild to moderate ulcerative colitis (inflammation of the colon). Lialda delayed-release tablets may also be used for other conditions as determined by your doctor.
Lialda delayed-release tablets are a 5-aminosalicylic acid (5-ASA). It works by preventing the production of substances that cause inflammation of the colon.
Do NOT use Lialda delayed-release tablets if:
- you are allergic to any ingredient in Lialda delayed-release tablets, nonsteroidal anti-inflammatory drugs (NSAIDs) (eg, ibuprofen, naproxen), or salicylates (eg, aspirin), or to sulfasalazine
- you are younger than 18 years old and you have the flu or chickenpox or have received a varicella or influenza vaccine within the past 6 weeks
- you are taking probenecid or sulfinpyrazone
Contact your doctor or health care provider right away if any of these apply to you.
Before using Lialda delayed-release tablets:
Some medical conditions may interact with Lialda delayed-release tablets. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
- if you are pregnant, planning to become pregnant, or are breast-feeding
- if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
- if you have allergies to medicines (including sulfasalazine), foods, or other substances
- if you have had a stroke, bleeding in the brain, or an aneurysm
- if you have a history of liver or kidney problems, certain stomach problems (pyloric stenosis), pancreas problems (eg, pancreatitis), Kawasaki syndrome, or a rheumatic (inflammatory) disease (eg, rheumatoid arthritis)
- if you have a history of heart problems (eg, inflammation of the sac around your heart)
- if you have the flu or chickenpox or have recently received a live vaccine (eg, varicella, influenza)
- if you have lung or breathing problems (eg, asthma), stomach or bowel ulcers, or urinary blockage
- if you have a blockage of the stomach or bowel
Some MEDICINES MAY INTERACT with Lialda delayed-release tablets. Tell your health care provider if you are taking any other medicines, especially any of the following:
- Nateglinide, repaglinide, or sulfonylureas (eg, glipizide) because the risk of low blood sugar may be increased
- Azathioprine or mercaptopurine because the risk of blood problems may be increased
- Gingko biloba extract because side effects, such as increased bleeding, may occur
- Corticosteroids (eg, prednisone) because they may decrease Lialda delayed-release tablets's effectiveness
- Carbonic anhydrase inhibitors (eg, acetazolamide) or valproic acid because the risk of their side effects may be increased by Lialda delayed-release tablets
- Angiotensin-converting enzyme (ACE) inhibitors (eg, enalapril), anticoagulants (eg, warfarin), beta-blockers (eg propranolol), probenecid, spironolactone, or sulfinpyrazone because their effectiveness may be decreased by Lialda delayed-release tablets
- Medicines that may harm the kidney (eg, aminoglycoside antibiotics [eg, gentamicin], amphotericin B, azathioprine, cyclosporine, NSAIDs [eg, ibuprofen], tacrolimus, vancomycin) because the risk of kidney side effects may be increased. Ask your doctor if you are unsure if any of your medicines might harm the kidney
This may not be a complete list of all interactions that may occur. Ask your health care provider if Lialda delayed-release tablets may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.
How to use Lialda delayed-release tablets:
Use Lialda delayed-release tablets as directed by your doctor. Check the label on the medicine for exact dosing instructions.
- Take Lialda delayed-release tablets by mouth with or without food or as directed by your doctor. If you are unsure how to take Lialda delayed-release tablets, contact your doctor or pharmacist.
- Swallow Lialda delayed-release tablets whole with liquid. Do not break, crush, or chew before swallowing. If you cannot swallow Lialda delayed-release tablets whole, contact your doctor.
- Continue to take Lialda delayed-release tablets even if you feel well. Do not miss any doses.
- If you miss a dose of Lialda delayed-release tablets, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.
Ask your health care provider any questions you may have about how to use Lialda delayed-release tablets.
Important safety information:
- Lialda delayed-release tablets may cause dizziness. This effect may be worse if you take it with alcohol or certain medicines. Use Lialda delayed-release tablets with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
- You may notice undissolved parts of Lialda delayed-release tablets in your stool with some brands of Lialda delayed-release tablets. If this occurs repeatedly, contact your doctor.
- Lialda delayed-release tablets may cause you to become sunburned more easily. Avoid the sun, sunlamps, or tanning booths until you know how you react to Lialda delayed-release tablets. Use a sunscreen or wear protective clothing if you must be outside for more than a short time.
- Some patients may experience an intolerance reaction to Lialda delayed-release tablets. Signs of intolerance are very similar to symptoms of an ulcerative colitis flare up or worsening ulcerative colitis symptoms. They may include severe or persistent stomach pain or cramping, bloody diarrhea, fever, headache, or rash. If you experience any of these symptoms, contact your doctor right away.
- Salicylates have been linked to a serious illness called Reye syndrome. Do not give Lialda delayed-release tablets to a child or teenager who has the flu, chickenpox, or a viral infection. Contact your doctor with any questions or concerns.
- Lab tests, including kidney function, liver function, and complete blood cell counts, may be performed while you use Lialda delayed-release tablets. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
- Use Lialda delayed-release tablets with caution in the ELDERLY; they may be more sensitive to its effects, especially blood problems.
- Lialda delayed-release tablets should be used with extreme caution in CHILDREN; safety and effectiveness in children have not been confirmed.
- PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Lialda delayed-release tablets while you are pregnant. Lialda delayed-release tablets are found in breast milk. If you are or will be breast-feeding while you use Lialda delayed-release tablets, check with your doctor. Discuss any possible risks to your baby.
Possible side effects of Lialda delayed-release tablets:
All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:
Seek medical attention right away if any of these SEVERE side effects occur:
Diarrhea; dizziness; gas; headache; indigestion; joint, muscle, or back pain; mild stomach pain; nausea; runny or stuffy nose; vomiting; weakness.
Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, throat, or tongue; unusual hoarseness); blood in the urine; bloody diarrhea; bloody or coffee ground-like vomit; burning, numbness, or tingling; change in the amount of urine produced; chest pain; confusion; fast or irregular heartbeat; fever, cough, chills, or persistent sore throat; severe or persistent headache or dizziness; severe or sudden stomach pain or cramping; severe stomach or back pain with nausea and vomiting; shortness of breath; sudden, unexplained weight gain; swelling of the hands, ankles, or feet; symptoms of liver problems (eg, dark urine; pale stools; severe or persistent nausea, loss of appetite, or stomach pain; unusual tiredness; yellowing of the skin or eyes); unusual bruising or bleeding; unusual tiredness or weakness.
This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.
If OVERDOSE is suspected:
Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately.Proper storage of Lialda delayed-release tablets:
Store Lialda delayed-release tablets at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Lialda delayed-release tablets out of the reach of children and away from pets.
- If you have any questions about Lialda delayed-release tablets, please talk with your doctor, pharmacist, or other health care provider.
- Lialda delayed-release tablets are to be used only by the patient for whom it is prescribed. Do not share it with other people.
- If your symptoms do not improve or if they become worse, check with your doctor.
- Check with your pharmacist about how to dispose of unused medicine.
This information should not be used to decide whether or not to take Lialda delayed-release tablets or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about Lialda delayed-release tablets. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to Lialda delayed-release tablets. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using Lialda delayed-release tablets.
Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.
More about Lialda (mesalamine)
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- Drug class: 5-aminosalicylates