Generic Name: Antihemophilic Factor (Human) (an tee hee moe FIL ik FAK tor HYU man)
Brand Name: Hemofil M, Koate, Koate-DVI, Monoclate-P
Medically reviewed by Drugs.com. Last updated on Dec 12, 2020.
Uses of Koate:
- It is used to treat hemophilia.
- It is used to treat or prevent bleeding.
What do I need to tell my doctor BEFORE I take Koate?
- If you are allergic to Koate (antihemophilic factor (human)); any part of Koate (antihemophilic factor (human)); or any other drugs, foods, or substances. Tell your doctor about the allergy and what signs you had.
- If you are allergic to mouse proteins, talk with the doctor.
This medicine may interact with other drugs or health problems.
Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take Koate (antihemophilic factor (human)) with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.
What are some things I need to know or do while I take Koate?
- Tell all of your health care providers that you take Koate (antihemophilic factor (human)). This includes your doctors, nurses, pharmacists, and dentists.
- If you have a latex allergy, talk with your doctor.
- Have blood work checked as you have been told by the doctor. Talk with the doctor.
- Call the doctor right away if the normal dose does not work as well.
- This medicine is made from human plasma (part of the blood) and may have viruses that may cause disease. This medicine is screened, tested, and treated to lower the chance that it carries an infection. Talk with the doctor.
- Talk with the doctor before you travel. You will need to bring enough of Koate (antihemophilic factor (human)) for use during travel.
- Tell your doctor if you are pregnant, plan on getting pregnant, or are breast-feeding. You will need to talk about the benefits and risks to you and the baby.
How is this medicine (Koate) best taken?
Use Koate (antihemophilic factor (human)) as ordered by your doctor. Read all information given to you. Follow all instructions closely.
- It is given as a shot into a vein.
- If you will be giving yourself the shot, your doctor or nurse will teach you how to give the shot.
- Wash your hands before and after use.
- This medicine needs to be mixed before use. Follow how to mix as you were told by the doctor.
- Use within 3 hours of making.
- Do not use if the solution is cloudy, leaking, or has particles.
- Do not use if solution changes color.
- Throw away any part left over after the dose is given.
- Throw away needles in a needle/sharp disposal box. Do not reuse needles or other items. When the box is full, follow all local rules for getting rid of it. Talk with a doctor or pharmacist if you have any questions.
What do I do if I miss a dose?
- Call your doctor to find out what to do.
What are some side effects that I need to call my doctor about right away?
WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:
- Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
- Signs of certain infections (parvovirus B19, hepatitis A) like fever or chills, feeling very sleepy, runny nose, rash, joint pain, tiredness, poor appetite, upset stomach or throwing up, belly pain, or yellow skin or eyes.
- Shortness of breath.
- Very bad dizziness or passing out.
- Feeling very tired or weak.
- Chest pain or pressure or a fast heartbeat.
- A burning, numbness, or tingling feeling that is not normal.
- Blurred eyesight.
What are some other side effects of Koate?
All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:
- Feeling nervous and excitable.
- Stomach pain.
- Upset stomach.
These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.
You may report side effects to the FDA at 1-800-332-1088. You may also report side effects at https://www.fda.gov/medwatch.
If OVERDOSE is suspected:
If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
How do I store and/or throw out Koate?
- Store at room temperature or in a refrigerator. Do not freeze.
Koate or Monoclate-P:
- Store in a refrigerator. Do not freeze.
- If needed, you may store at room temperature for up to 6 months. Write down the date you take Koate (antihemophilic factor (human)) out of the refrigerator. If stored at room temperature and not used within 6 months, throw Koate (antihemophilic factor (human)) away.
- After mixing, do not refrigerate.
- Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
- Throw away unused or expired drugs. Do not flush down a toilet or pour down a drain unless you are told to do so. Check with your pharmacist if you have questions about the best way to throw out drugs. There may be drug take-back programs in your area.
Consumer information use
- If your symptoms or health problems do not get better or if they become worse, call your doctor.
- Do not share your drugs with others and do not take anyone else's drugs.
- Some drugs may have another patient information leaflet. Check with your pharmacist. If you have any questions about Koate (antihemophilic factor (human)), please talk with your doctor, nurse, pharmacist, or other health care provider.
- If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Frequently Asked Questions
More about Koate (antihemophilic factor)
- Side Effects
- During Pregnancy or Breastfeeding
- Dosage Information
- Drug Interactions
- Drug class: miscellaneous coagulation modifiers