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Generic Name: Iopamidol (eye oh PA mi dole)
Brand Name: Isovue-200, Isovue-250, Isovue-300, Isovue-370, Isovue-M 200, all 6 brand names.

Medically reviewed by Last updated on Sep 25, 2020.


  • Some products must not be given into the spine. Very bad and sometimes deadly health problems have happened when these products were given into the spine. This includes coma, heart attack, kidney failure, paralysis, seizures, high body temperature, a muscle problem called rhabdomyolysis, or brain problems like bleeding or swelling. Talk with the doctor.

Uses of Isovue-200:

  • It is used before an x-ray or an alike test.

What do I need to tell my doctor BEFORE I take Isovue-200?

All products:

  • If you have an allergy to iopamidol or any other part of Isovue-200 (iopamidol).
  • If you are allergic to Isovue-200 (iopamidol); any part of Isovue-200 (iopamidol); or any other drugs, foods, or substances. Tell your doctor about the allergy and what signs you had.
  • If you are dehydrated, have been eating poorly, or have used a laxative or water pill before Isovue-200 (iopamidol).
  • If you have a health problem called homocystinuria.
  • If you have had a skin reaction to Isovue-200 (iopamidol) or another drug like it in the past.
  • If you are taking metformin.

Injection (if given into the spine):

  • If you have an infection.

This is not a list of all drugs or health problems that interact with Isovue-200 (iopamidol).

Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take Isovue-200 (iopamidol) with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.

What are some things I need to know or do while I take Isovue-200?

  • Tell all of your health care providers that you take Isovue-200 (iopamidol). This includes your doctors, nurses, pharmacists, and dentists.
  • Very bad and sometimes deadly allergic reactions have rarely happened. Talk with your doctor.
  • Health problems like blood clots have happened with Isovue-200 (iopamidol) when used with some procedures. Sometimes, blood clots may cause heart attack and stroke, which may be deadly. If you have questions, talk with the doctor.
  • Thyroid problems have happened after use of Isovue-200 (iopamidol). Some people had to be treated for these thyroid problems. Talk with the doctor.
  • A severe and sometimes deadly reaction has happened. Most of the time, this reaction has signs like fever, rash, or swollen glands with problems in body organs like the liver, kidney, blood, heart, muscles and joints, or lungs. If you have questions, talk with the doctor.
  • If you have sickle cell disease, talk with your doctor.
  • This medicine may affect certain lab tests. Tell all of your health care providers and lab workers that you take Isovue-200 (iopamidol).
  • If you are 65 or older, use Isovue-200 (iopamidol) with care. You could have more side effects.
  • Use with care in children. Talk with the doctor.
  • Tell your doctor if you are pregnant or plan on getting pregnant. You will need to talk about the benefits and risks of using Isovue-200 (iopamidol) while you are pregnant.
  • Tell your doctor if you are breast-feeding. You will need to talk about any risks to your baby.

How is this medicine (Isovue-200) best taken?

Use Isovue-200 (iopamidol) as ordered by your doctor. Read all information given to you. Follow all instructions closely.

  • Your doctor will give Isovue-200 (iopamidol).
  • You will need to be sure that you are not dehydrated before getting Isovue-200 (iopamidol). Check with your doctor to see if you need to drink extra fluids before getting Isovue-200 (iopamidol).
  • Drink lots of noncaffeine liquids after using Isovue-200 (iopamidol) unless told to drink less liquid by your doctor.

What do I do if I miss a dose?

  • Call your doctor to find out what to do.

What are some side effects that I need to call my doctor about right away?

WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:

All products:

  • Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
  • Signs of kidney problems like unable to pass urine, change in how much urine is passed, blood in the urine, or a big weight gain.
  • Chest pain or pressure or a fast heartbeat.
  • A heartbeat that does not feel normal.
  • Very bad dizziness or passing out.
  • Weakness on 1 side of the body, trouble speaking or thinking, change in balance, drooping on one side of the face, or blurred eyesight.
  • This medicine may cause tissue damage if the drug leaks from the vein. Tell your nurse if you have any redness, burning, pain, swelling, blisters, skin sores, or leaking of fluid where the drug is going into your body.
  • Very bad skin reactions (Stevens-Johnson syndrome/toxic epidermal necrolysis) may happen from 1 hour to several weeks after getting this drug. These skin reactions can cause very bad health problems that may not go away, and sometimes death. Get medical help right away if you have signs like red, swollen, blistered, or peeling skin (with or without fever); red or irritated eyes; or sores in your mouth, throat, nose, or eyes.

Injection (if given into the spine):

What are some other side effects of Isovue-200?

All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:

Injection (if given into the spine):

All other injection products:

These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.

You may report side effects to the FDA at 1-800-332-1088. You may also report side effects at

If OVERDOSE is suspected:

If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

How do I store and/or throw out Isovue-200?

  • If you need to store Isovue-200 (iopamidol) at home, talk with your doctor, nurse, or pharmacist about how to store it.

Consumer information use

  • If your symptoms or health problems do not get better or if they become worse, call your doctor.
  • Do not share your drugs with others and do not take anyone else's drugs.
  • Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
  • Throw away unused or expired drugs. Do not flush down a toilet or pour down a drain unless you are told to do so. Check with your pharmacist if you have questions about the best way to throw out drugs. There may be drug take-back programs in your area.
  • Some drugs may have another patient information leaflet. Check with your pharmacist. If you have any questions about Isovue-200 (iopamidol), please talk with your doctor, nurse, pharmacist, or other health care provider.
  • If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.