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Generic Name: iron polysaccharide/vitamins/folic acid/intrinsic factor/senna (EYE-urn PAHL-ee-SAA-kah-ride/VYE-ta-mins/FOE-lik AS-id/in-TRIN-sik FAK-tor/SEN-a)
Brand Name: Iro-Plex

Accidental overdose of iron-containing products is a leading cause of fatal poisoning in children younger than 6 years old. Keep this and all medicines out of reach of children. In case of accidental ingestion, call the poison control center or a doctor immediately.

Iro-Plex is used for:

Treating and preventing low levels of iron in the blood caused by certain types of anemia. It may also be used for other conditions as determined by your doctor.

Iro-Plex is a combination of iron, vitamins, folic acid, and a stomach absorption substance. It also contains senna, which is a laxative. Iro-Plex works by replacing iron, certain vitamins, and folic acid in your body. The stomach absorption substance helps the body to absorb Iro-Plex. The senna is used to treat constipation that may be caused by the iron in Iro-Plex.

Do NOT use Iro-Plex if:

  • you are allergic to any ingredient in Iro-Plex
  • you have high levels of iron in your blood

Contact your doctor or health care provider right away if any of these apply to you.

Before using Iro-Plex:

Some medical conditions may interact with Iro-Plex. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have inflammation of the intestines, Crohn disease, digestive problems, ulcers, anemia, or a blood disease (eg, porphyria, thalassemia)
  • if you have had multiple blood transfusions
  • if you have a history of alcohol abuse or if you have had recent stomach or bowel surgery

Some MEDICINES MAY INTERACT with Iro-Plex. Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Fluorouracil because the risk of its side effects may be increased by Iro-Plex
  • Doxycycline, hydantoins (eg, phenytoin), penicillamine, or thyroid hormones (eg, levothyroxine) because their effectiveness may be decreased by Iro-Plex

This may not be a complete list of all interactions that may occur. Ask your health care provider if Iro-Plex may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Iro-Plex:

Use Iro-Plex as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Take Iro-Plex by mouth with food.
  • Use a measuring device marked for medicine dosing. Ask your pharmacist for help if you are unsure of how to measure your dose.
  • Do not take Iro-Plex within 1 hour before or 2 hours after antacids, eggs, whole grain breads, cereal, milk, milk products, coffee, or tea.
  • Take Iro-Plex with a full glass of water (8 oz/240 mL). Do not lie down for 30 minutes after taking Iro-Plex.
  • If you are also taking a bisphosphonate (eg, alendronate), a cephalosporin (eg, cefdinir), methyldopa, penicillamine, a quinolone (eg, ciprofloxacin), or a tetracycline (eg, minocycline) along with Iro-Plex, you may need to space the doses several hours apart. Ask your doctor or pharmacist how much time is needed between doses of Iro-Plex and your other medicines.
  • If you miss a dose of Iro-Plex, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Iro-Plex.

Important safety information:

  • Do not take large doses of vitamins (megadoses or megavitamin therapy) while you take Iro-Plex unless your doctor tells you to.
  • Do not take more than the recommended dose or take Iro-Plex for longer than 6 months without checking with your doctor.
  • Iro-Plex may cause your stools to darken. This is normal and not a cause for concern.
  • Iro-Plex contains iron. Accidental overdose of iron-containing products is a leading cause of fatal poisoning in children younger than 6 years of age. In case of accidental overdose, call a doctor or poison control center immediately.
  • Iro-Plex has folic acid and vitamin B6 in it. Before you start any new medicine, check the label to see if it has folic acid or vitamin B6 in it too. If it does or if you are not sure, check with your doctor or pharmacist.
  • Iro-Plex may interfere with certain lab tests, including tests used to check for blood in the stool. Be sure your doctor and lab personnel know you are taking Iro-Plex.
  • Lab tests, including blood tests and iron levels, may be performed while you use Iro-Plex. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
  • Iro-Plex should be used with extreme caution in CHILDREN; safety and effectiveness in children have not been confirmed.
  • PREGNANCY and BREAST-FEEDING: If you think you may be pregnant, contact your doctor. You will need to discuss the benefits and risks of taking Iro-Plex while you are pregnant. Iro-Plex is found in breast milk. If you are or will be breast-feeding while you take Iro-Plex, check with your doctor. Discuss any possible risks to your baby.

Possible side effects of Iro-Plex:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Constipation; darkened or green stools; diarrhea; nausea; stomach upset.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); black, tarry stools; blood or streaks of blood in the stool; fever; rectal bleeding; severe or persistent diarrhea; vomiting, especially with continuing sharp stomach pain.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include difficulty breathing; loss of consciousness; seizures; severe nausea or diarrhea; stomach pain; tarry stools; unusual tiredness or drowsiness; unusually pale skin; vomiting; vomiting blood; weak, fast heartbeat.

Proper storage of Iro-Plex:

Store Iro-Plex at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Iro-Plex out of the reach of children and away from pets.

General information:

  • If you have any questions about Iro-Plex, please talk with your doctor, pharmacist, or other health care provider.
  • Iro-Plex is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.
  • Check with your pharmacist about how to dispose of unused medicine.

This information should not be used to decide whether or not to take Iro-Plex or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about Iro-Plex. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to Iro-Plex. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using Iro-Plex.

Issue Date: June 3, 2015

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.