Generic Name: Telaprevir (tel A pre vir)
Brand Name: Incivek
Medically reviewed on July 4, 2018
- This medicine can cause very bad and sometimes deadly skin side effects when taken with peginterferon alfa and ribavirin. Talk to your doctor about any skin changes you may have.
The Incivek brand name has been discontinued in the U.S. If generic versions of this product have been approved by the FDA, there may be generic equivalents available.
Uses of Incivek:
- It is used to treat hepatitis C infection.
What do I need to tell my doctor BEFORE I take Incivek?
- If you have an allergy to telaprevir or any other part of Incivek (telaprevir).
- If you are allergic to any drugs like this one, any other drugs, foods, or other substances. Tell your doctor about the allergy and what signs you had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
- If you are not taking ribavirin or peginterferon alfa.
- If you have liver disease.
- If you take any drugs (prescription, OTC, natural products, vitamins) that must not be taken with Incivek (telaprevir), like certain drugs that are used for high cholesterol, seizures, migraines, or rifampin. There are many drugs that must not be taken with Incivek (telaprevir).
- If you are of childbearing age, but are not using 2 kinds of birth control or if you are planning to get pregnant during your care or within 6 months after care has ended.
- If you are a man with a sex partner who is pregnant or plans on getting pregnant at any time while you are being treated or within 6 months after your care has ended.
- If you are pregnant or may be pregnant. Do not take Incivek (telaprevir) if you are pregnant.
This is not a list of all drugs or health problems that interact with Incivek (telaprevir).
Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take Incivek (telaprevir) with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.
What are some things I need to know or do while I take Incivek?
- Tell all of your health care providers that you take Incivek (telaprevir). This includes your doctors, nurses, pharmacists, and dentists.
- You may bleed more easily. Be careful and avoid injury. Use a soft toothbrush and an electric razor.
- Have blood work checked as you have been told by the doctor. Talk with the doctor.
- Do not take St John's wort with Incivek (telaprevir). This medicine may not work as well.
- This medicine does not stop the spread of diseases like HIV or hepatitis that are passed through blood or having sex. Do not have any kind of sex without using a latex or polyurethane condom. Do not share needles or other things like toothbrushes or razors. Talk with your doctor.
- This medicine may cause harm to the unborn baby if you take it while you are pregnant.
- Use 2 kinds of birth control that you can trust while using Incivek (telaprevir) and for 6 months after stopping Incivek (telaprevir).
- If you are a man and have sex with a female who could get pregnant, protect her from pregnancy during care and for 6 months after care ends. Use birth control that you can trust.
- Do not use a hormone-related kind of birth control.
- Tell your doctor if you are breast-feeding. You will need to talk about any risks to your baby.
How is this medicine (Incivek) best taken?
Use Incivek (telaprevir) as ordered by your doctor. Read all information given to you. Follow all instructions closely.
- To gain the most benefit, do not miss doses.
- Take Incivek (telaprevir) at the same time of day.
- Keep taking Incivek (telaprevir) as you have been told by your doctor or other health care provider, even if you feel well.
- Take with a high-fat meal.
- Swallow whole. Do not chew, break, or crush.
- Drink lots of noncaffeine liquids unless told to drink less liquid by your doctor.
What do I do if I miss a dose?
- If it has been 6 hours or more since the missed dose, skip the missed dose and go back to your normal time.
- If it has been less than 6 hours since a normal dose, take a missed dose as soon as you think about it and go back to your normal time.
- Do not use 2 doses or extra doses.
See also: Dosage Information (in more detail)
What are some side effects that I need to call my doctor about right away?
WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:
- Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
- Signs of fluid and electrolyte problems like mood changes, confusion, muscle pain or weakness, a heartbeat that does not feel normal, very bad dizziness or passing out, fast heartbeat, more thirst, seizures, feeling very tired or weak, not hungry, unable to pass urine or change in the amount of urine produced, dry mouth, dry eyes, or very bad upset stomach or throwing up.
- Shortness of breath.
- Feeling very tired or weak.
- A very bad skin reaction (Stevens-Johnson syndrome/toxic epidermal necrolysis) may happen. It can cause very bad health problems that may not go away, and sometimes death. Get medical help right away if you have signs like red, swollen, blistered, or peeling skin (with or without fever); red or irritated eyes; or sores in your mouth, throat, nose, or eyes.
What are some other side effects of Incivek?
All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:
- Feeling tired or weak.
- Feeling sleepy.
- Bad taste in your mouth.
- Upset stomach or throwing up.
- Loose stools (diarrhea).
- Anal irritation.
These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.
You may report side effects to the FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.
See also: Side effects (in more detail)
If OVERDOSE is suspected:
If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
How do I store and/or throw out Incivek?
- Store at room temperature.
- Store in a dry place. Do not store in a bathroom.
- Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
- Throw away unused or expired drugs. Do not flush down a toilet or pour down a drain unless you are told to do so. Check with your pharmacist if you have questions about the best way to throw out drugs. There may be drug take-back programs in your area.
Consumer information use
- If your symptoms or health problems do not get better or if they become worse, call your doctor.
- Do not share your drugs with others and do not take anyone else's drugs.
- Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
- Talk with the doctor before starting any new drug, including prescription or OTC, natural products, or vitamins.
- This medicine comes with an extra patient fact sheet called a Medication Guide. Read it with care. Read it again each time Incivek (telaprevir) is refilled. If you have any questions about Incivek (telaprevir), please talk with the doctor, pharmacist, or other health care provider.
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
More about Incivek (telaprevir)
- Incivek Side Effects
- During Pregnancy
- Dosage Information
- Drug Images
- Drug Interactions
- Support Group
- 7 Reviews
- Drug class: protease inhibitors