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Gramicidin, neomycin, and polymyxin B ophthalmic

Generic name: gramicidin, neomycin, and polymyxin B ophthalmic [ gram-i-SYE-din, NEE-oh-MYE-sin, POL-ee-MIX-in-B-off-THAL-mik ]
Brand names: Neosporin Ophthalmic, Neocidin, AK-Spore, Neocin PG, Neoptic, Ocu-Spore-G
Dosage form: ophthalmic solution (0.025 mg-1.75 mg-10000 units/mL)
Drug class: Ophthalmic anti-infectives

Medically reviewed by Drugs.com on Aug 4, 2023. Written by Cerner Multum.

What is gramicidin, neomycin, and polymyxin B ophthalmic?

Gramicidin, neomycin, and polymyxin B are antibiotics that fight bacteria.

Gramicidin, neomycin, and polymyxin B ophthalmic (for the eyes) is a combination medicine used to treat bacterial eye infections such as conjunctivitis (pink eye) or blepharitis (eyelid inflammation).

Gramicidin, neomycin, and polymyxin B ophthalmic may also be used for purposes not listed in this medication guide.

gramicidin, neomycin, and polymyxin B ophthalmic side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

This medicine may cause serious side effects. Stop using this medicine and call your doctor at once if you have:

Common side effects of gramicidin, neomycin, and polymyxin B ophthalmic may include:

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Warnings

Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.

Before taking this medicine

You should not use this medicine if you are allergic to gramicidin, neomycin, or polymyxin B, or if you have a viral or fungal infection in your eye.

Tell your doctor if you have ever had an allergy to certain antibiotics (kanamycin, paromomycin, streptomycin, or gentamicin).

Tell your doctor if you are pregnant or breastfeeding.

Gramicidin, neomycin, and polymyxin B ophthalmic is not approved for use by anyone younger than 18 years old.

How should I use gramicidin, neomycin, and polymyxin B ophthalmic?

Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.

Wash your hands before using eye medication.

To apply the eye drops: Tilt your head back slightly and pull down your lower eyelid to create a small pocket. Hold the dropper above the eye and squeeze a drop into this pocket. Close your eyes for 1 or 2 minutes.

Use only the number of drops your doctor has prescribed. Wait at least 5 minutes before using any other eye drops your doctor has prescribed.

Do not touch the tip of the eye dropper or place it directly on your eye. A contaminated dropper can infect your eye, which could lead to serious vision problems.

Store at room temperature, away from heat and light. Keep the bottle tightly closed when not in use.

What happens if I miss a dose?

Use the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not use two doses at one time.

What happens if I overdose?

An overdose of gramicidin, neomycin, and polymyxin B ophthalmic is not expected to be dangerous. Seek emergency medical attention or call the Poison Help line at 1-800-222-1222 if anyone has accidentally swallowed the medication.

What should I avoid while using gramicidin, neomycin, and polymyxin B ophthalmic?

Do not share this medicine with another person, or the eye dropper could spread infection.

This medicine may cause blurred vision and may impair your reactions. Avoid driving or hazardous activity until you know how this medicine will affect you.

Do not use other eye medications unless your doctor tells you to.

What other drugs will affect gramicidin, neomycin, and polymyxin B ophthalmic?

Medicine used in the eyes is not likely to be affected by other drugs you use. But many drugs can interact with each other. Tell each of your healthcare providers about all medicines you use, including prescription and over-the-counter medicines, vitamins, and herbal products.

Further information

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.