Generic Name: glycopyrrolate (GLYE-koe-PIR-oh-late)
Brand Name: Cuvposa
Glycopyrrolate solution is used for:
Reducing chronic, severe drooling caused by certain conditions (eg, cerebral palsy) in patients 3 to 16 years old. It may also be used for other conditions as determined by your doctor.
Glycopyrrolate solution is an anticholinergic. It works by blocking the activity of the glands that produce saliva.
Do NOT use glycopyrrolate solution if:
- you are allergic to any ingredient in glycopyrrolate solution
- you have glaucoma, trouble urinating, certain stomach or bowel problems (eg, blockage, bowel muscle problems, severe ulcerative colitis, toxic megacolon), myasthenia gravis, or heart problems caused by bleeding
- you are taking a solid oral doseform of potassium (eg, tablet)
Contact your doctor or health care provider right away if any of these apply to you.
Before using glycopyrrolate solution:
Some medical conditions may interact with glycopyrrolate solution. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
- if you are pregnant, planning to become pregnant, or are breast-feeding
- if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
- if you have allergies to medicines, foods, or other substances
- if you have nerve problems (eg, autonomic neuropathy), liver or kidney problems, thyroid problems, eye problems (eg, increased pressure in the eye), or a family history of glaucoma
- if you have heart problems (eg, coronary heart disease, heart failure), fast or irregular heartbeat, or high blood pressure
- if you have stomach or bowel problems (eg, ulcerative colitis), a hiatal hernia caused by reflux disease, or if you have an ileostomy or colostomy
- if you have a history of constipation problems
Some MEDICINES MAY INTERACT with glycopyrrolate solution. Tell your health care provider if you are taking any other medicines, especially any of the following:
- Amantadine because it may increase the risk of glycopyrrolate solution's side effects
- Atenolol, digoxin, or metformin because the risk of their side effects may be increased by glycopyrrolate solution
- Haloperidol or levodopa because their effectiveness may be decreased by glycopyrrolate solution
This may not be a complete list of all interactions that may occur. Ask your health care provider if glycopyrrolate solution may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.
How to use glycopyrrolate solution:
Use glycopyrrolate solution as directed by your doctor. Check the label on the medicine for exact dosing instructions.
- An extra patient leaflet is available with glycopyrrolate solution. Talk to your pharmacist if you have questions about this information.
- Take glycopyrrolate solution by mouth on an empty stomach at least 1 hour before or 2 hours after eating.
- Use a measuring cup and oral syringe marked for medicine dosing. Use the measuring cup to measure the correct dose, then use the oral syringe to transfer the medicine from the cup to the mouth. Ask your pharmacist for help if you are unsure of how to measure your dose.
- Take glycopyrrolate solution on a regular schedule to get the most benefit from it.
- Continue to take glycopyrrolate solution even if your condition improves. Do not miss any doses.
- If you miss a dose of glycopyrrolate solution, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.
Ask your health care provider any questions you may have about how to use glycopyrrolate solution.
Important safety information:
- Glycopyrrolate solution may cause drowsiness or blurred vision. These effects may be worse if you take it with alcohol or certain medicines. Use glycopyrrolate solution with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
- Do NOT take more than the recommended dose without checking with your doctor.
- Do not become overheated in hot weather or while you are being active; heatstroke may occur.
- If constipation occurs, contact your doctor for instructions.
- Glycopyrrolate solution should be used with extreme caution in CHILDREN younger than 3 years old; safety and effectiveness in these children have not been confirmed.
- PREGNANCY and BREAST-FEEDING: It is not known if glycopyrrolate solution can cause harm to the fetus. If you become pregnant, contact your doctor. Your will need to discuss the benefits and risks of using glycopyrrolate solution while you are pregnant. It is not known if this medicine is found in breast milk. If you are or will be breast-feeding while you use glycopyrrolate solution, check with your doctor. Discuss any possible risks to your baby.
Possible side effects of glycopyrrolate solution:
All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:
Seek medical attention right away if any of these SEVERE side effects occur:
Blurred vision; constipation; drowsiness; dry mouth; flushing; headache; nasal congestion; upper respiratory infection; vomiting.
Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); diarrhea; frequent or painful urination; mental or mood changes (eg, irritability, crying); seizures; severe or persistent nausea or vomiting; stomach pain or bloating; symptoms of dehydration (eg, very dry mouth, skin, or eyes; fast or irregular heartbeat); symptoms of heatstroke (eg, fever; hot, red skin; decreased alertness; fast, weak pulse; fast, shallow breathing); trouble urinating.
This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.
If OVERDOSE is suspected:
Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include coma; fever; muscle pain; seizures; stomach pain or bloating; uncontrolled muscle movements.Proper storage of glycopyrrolate solution:
Store glycopyrrolate solution at room temperature between 68 and 77 degrees F (20 and 25 degrees C). Brief storage at temperatures between 59 and 86 degrees F (15 and 30 degrees C) is permitted. Store away from heat, moisture, and light. Do not store in the bathroom. Keep glycopyrrolate solution out of the reach of children and away from pets.
- If you have any questions about glycopyrrolate solution, please talk with your doctor, pharmacist, or other health care provider.
- Glycopyrrolate solution is to be used only by the patient for whom it is prescribed. Do not share it with other people.
- If your symptoms do not improve or if they become worse, check with your doctor.
- Check with your pharmacist about how to dispose of unused medicine.
This information should not be used to decide whether or not to take glycopyrrolate solution or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about glycopyrrolate solution. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to glycopyrrolate solution. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using glycopyrrolate solution.
Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.
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