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Gatifloxacin tablets

Generic Name: gatifloxacin (ga-ti-FLOKS-a-sin)
Brand Name: Tequin

Gatifloxacin tablets are used for:

Treating infections caused by certain bacteria.

Gatifloxacin tablets are a fluoroquinolone antibiotic. It works by stopping the production of proteins that bacteria need to survive.

Do NOT use gatifloxacin tablets if:

  • you are allergic to any ingredient in gatifloxacin tablets or to similar medicines (eg, ciprofloxacin)
  • you have low blood potassium or diabetes
  • you or a family member have a rare heart condition known as congenital prolongation of the QTc interval
  • you are taking certain medicines for heart rhythm disturbances (eg, quinidine, procainamide, amiodarone, sotalol), cisapride, a ketolide antibiotic (eg, telithromycin), a macrolide antibiotic (eg, erythromycin), pimozide, or ziprasidone

Contact your doctor or health care provider right away if any of these apply to you.

Before using gatifloxacin tablets:

Some medical conditions may interact with gatifloxacin tablets. Tell your health care provider if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have heart problems, including a slow heartbeat, a history of lack of blood supply to your heart, or hardening of the arteries
  • if you have a history of low blood potassium levels, diabetes, or kidney or liver problems
  • if you have Alzheimer disease, tendonitis, or a history of seizures
  • if you have a central nervous system disease or increased pressure in the head

Some MEDICINES MAY INTERACT with gatifloxacin tablets. Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Antidepressants (eg, amitriptyline), antihistamines (eg, diphenhydramine, loratadine), arsenic, azole antifungals (eg, ketoconazole), certain medicines for heart rhythm disturbances (eg, quinidine, procainamide, amiodarone, sotalol), cisapride, diuretics (eg, hydrochlorothiazide, furosemide), droperidol, ketolide antibiotics (eg, telithromycin, macrolide antibiotics (eg, erythromycin), phenothiazines (eg, chlorpromazine), pimozide , or ziprasidone because the risk of side effects, such as racing heartbeat, dizziness, fainting, life-threatening irregular heartbeat leading to unconsciousness, may be increased
  • Probenecid because it may increase the risk of gatifloxacin tablets's side effects
  • Digoxin because the risk of its side effects may be increased by gatifloxacin tablets
  • Anticoagulants (eg, warfarin) because the risk of side effects, including bleeding, may be increased
  • Insulin, sulfonylureas (eg, glyburide), or other medicines for diabetes because the risk of blood sugar changes may be increased

This may not be a complete list of all interactions that may occur. Ask your health care provider if gatifloxacin tablets may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use gatifloxacin tablets:

Use gatifloxacin tablets as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Gatifloxacin tablets may be taken with or without food.
  • Gatifloxacin tablets works best if it is taken at the same time each day.
  • Gatifloxacin tablets should be taken 4 hours before any other medicines or dietary supplements that contain aluminum, buffered didanosine, calcium, iron, magnesium, sucralfate, or zinc.
  • Swallow whole. Do not break, crush, or chew before swallowing.
  • To clear up your infection completely, continue using gatifloxacin tablets for the full course of treatment even if you feel better in a few days.
  • If you have trouble swallowing, talk with your doctor about taking the oral solution.
  • Do not miss any doses of gatifloxacin tablets. If you miss a dose, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use gatifloxacin tablets.

Important safety information:

  • Gatifloxacin tablets may cause dizziness, drowsiness, or changes in vision. Do not drive, operate machinery, or do anything else that could be dangerous until you know how you react to gatifloxacin tablets. Using gatifloxacin tablets alone, with certain other medicines, or with alcohol may lessen your ability to drive or perform other potentially dangerous tasks.
  • Gatifloxacin tablets are effective only against bacteria. It is not effective for treating viral infections (eg, the common cold).
  • It is important to use gatifloxacin tablets for the full course of treatment. Failure to do so may decrease the effectiveness of gatifloxacin tablets and may increase the risk that the bacteria will no longer be sensitive to gatifloxacin tablets and will not be able to be treated by this or certain other antibiotics in the future.
  • Long-term or repeated use of gatifloxacin tablets may cause a second infection. Your doctor may want to change your medicine to treat the second infection. Contact your doctor if signs of a second infection occur.
  • If severe diarrhea, stomach pain/cramps, or bloody stools occur, contact your doctor immediately. This could be a symptom of a serious side effect requiring immediate medical attention. Do not treat diarrhea without consulting your doctor.
  • Gatifloxacin tablets may cause increased sensitivity to the sun. Avoid exposure to the sun, sunlamps, or tanning booths until you know how you react to gatifloxacin tablets. Use a sunscreen or wear protective clothing if you must be outside for a prolonged period.
  • Gatifloxacin tablets may cause low blood sugar (eg, increased heartbeat, headache, chills, sweating, tremor, increased hunger, changes in vision, nervousness, weakness, dizziness, drowsiness, fainting) or high blood sugar (eg, thirst, increased urination, confusion, drowsiness, flushing, rapid breathing, fruity breath odor). If these symptoms occur, tell your doctor immediately.
  • Use gatifloxacin tablets with caution in the ELDERLY because they may be more sensitive to its effects, especially blood sugar changes.
  • Gatifloxacin tablets are not recommended for use in CHILDREN younger than 18 years of age. Safety and effectiveness in this age group have not been confirmed.
  • PREGNANCY and BREAST-FEEDING: If you become pregnant, discuss with your doctor the benefits and risks of using gatifloxacin tablets during pregnancy. It is unknown if gatifloxacin tablets are excreted in breast milk. If you are or will be breast-feeding while you are using gatifloxacin tablets, check with your doctor or pharmacist to discuss the risks to your baby.

Possible side effects of gatifloxacin tablets:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Diarrhea; dizziness; drowsiness; headache; mild diarrhea; nausea; stomachache; vaginal irritation; vomiting.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); bloody stools; changes in mood or behavior; chest pain or pounding in the chest; confusion; depression; excessive hunger, thirst, or urination; fainting; fast or irregular heartbeat; fruity breath odor; hallucinations; hoarseness; lightheadedness; loss of consciousness; nervousness; nightmares; pale skin; paranoia; restlessness; seizures; severe or continuous diarrhea; sleeplessness; stomach pain/cramps; sweating; tendon or joint pain or swelling; tremors; unusual or severe drowsiness or dizziness; vision changes.

This is not a complete list of all side effects that may occur. If you have questions or need medical advice about side effects, contact your doctor or health care provider. You may report side effects to the FDA at 1-800-FDA-1088 (1-800-332-1088) or at

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (, or emergency room immediately.

Proper storage of gatifloxacin tablets:

Store gatifloxacin tablets at 77 degrees F (25 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Brief storage at temperatures between 59 and 86 degrees F (15 and 30 degrees C) is permitted. Keep gatifloxacin tablets out of the reach of children and away from pets.

General information:

  • If you have any questions about gatifloxacin tablets, please talk with your doctor, pharmacist, or other health care provider.
  • Gatifloxacin tablets are to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about gatifloxacin tablets. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Review Date: March 1, 2017

Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.