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Fycompa (Oral Suspension)

Generic name: Perampanel Oral Suspension (per AM pa nel)
Brand name: Fycompa
Drug class: AMPA receptor antagonists

Medically reviewed by Last updated on Dec 27, 2020.


  • New or worse mental, mood, or behavior problems have happened with Fycompa (perampanel oral suspension). These problems include thoughts of suicide or murder, depression, forceful actions, fury, anxiety, and anger. These problems have happened in people with and without a history of mental or mood problems. Watch people who take Fycompa (perampanel oral suspension) closely. If you think you have any of these problems, call your doctor right away. Call your doctor right away if you have any other signs like nervousness, restlessness, grouchiness, panic attacks, or any new or worse changes in mood or actions.

Uses of Fycompa:

  • It is used to help control certain kinds of seizures.

What do I need to tell my doctor BEFORE I take Fycompa?

  • If you have an allergy to perampanel or any other part of Fycompa (perampanel oral suspension).
  • If you are allergic to Fycompa (perampanel oral suspension); any part of Fycompa (perampanel oral suspension); or any other drugs, foods, or substances. Tell your doctor about the allergy and what signs you had.
  • If you have any of these health problems: Kidney disease or liver disease.

This is not a list of all drugs or health problems that interact with Fycompa (perampanel oral suspension).

Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take Fycompa (perampanel oral suspension) with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.

What are some things I need to know or do while I take Fycompa?

  • Tell all of your health care providers that you take Fycompa (perampanel oral suspension). This includes your doctors, nurses, pharmacists, and dentists.
  • Avoid driving and doing other tasks or actions that call for you to be alert until you see how Fycompa (perampanel oral suspension) affects you.
  • Talk with your doctor before you drink alcohol or use other drugs and natural products that slow your actions.
  • Do not stop taking Fycompa (perampanel oral suspension) all of a sudden without calling your doctor. You may have a greater risk of seizures. If you need to stop this drug, you will want to slowly stop it as ordered by your doctor.
  • The chance of falling is raised with Fycompa (perampanel oral suspension). Falls may lead to very bad problems like head injury and broken bones. The chance of falling is higher in older people. Talk with the doctor.
  • If you are 65 or older, use Fycompa (perampanel oral suspension) with care. You could have more side effects.
  • Birth control pills and other hormone-based birth control products that have levonorgestrel in them may not work as well to prevent pregnancy. Use some other kind of birth control also like a condom if you are using a birth control product with levonorgestrel in it and for 1 month after your last dose of Fycompa (perampanel oral suspension). If you have questions, talk with your doctor.
  • Tell your doctor if you are pregnant, plan on getting pregnant, or are breast-feeding. You will need to talk about the benefits and risks to you and the baby.

How is this medicine (Fycompa) best taken?

Use Fycompa (perampanel oral suspension) as ordered by your doctor. Read all information given to you. Follow all instructions closely.

  • If the adapter has not been put in the bottle when you get it, follow how to prepare the bottle as you have been told or read the package insert.
  • Take Fycompa (perampanel oral suspension) at bedtime.
  • Shake well before use.
  • Measure liquid doses carefully. Use the measuring device that comes with Fycompa (perampanel oral suspension). If there is none, ask the pharmacist for a device to measure Fycompa (perampanel oral suspension).
  • Do not use a household teaspoon or tablespoon to measure Fycompa (perampanel oral suspension). Doing so could lead to the dose being too high.
  • Keep taking Fycompa (perampanel oral suspension) as you have been told by your doctor or other health care provider, even if you feel well.

What do I do if I miss a dose?

  • Skip the missed dose and go back to your normal time.
  • Do not take 2 doses at the same time or extra doses.
  • If you miss more than 1 day of taking Fycompa (perampanel oral suspension), talk with your doctor.

What are some side effects that I need to call my doctor about right away?

WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:

  • Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
  • Feeling confused.
  • Hallucinations (seeing or hearing things that are not there).
  • Memory problems or loss.
  • Change in balance.
  • Very bad dizziness or passing out.
  • Trouble walking.
  • Shortness of breath, a big weight gain, or swelling in the arms or legs.
  • A very bad and sometimes deadly effect has happened in people taking drugs for seizures like Fycompa (perampanel oral suspension). Call your doctor right away if you have swollen glands; fever; rash; chest pain; unable to pass urine or change in the amount of urine passed; or signs of liver problems like dark urine, feeling tired, not hungry, upset stomach or stomach pain, light-colored stools, throwing up, or yellow skin or eyes.

What are some other side effects of Fycompa?

All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:

  • Feeling dizzy, sleepy, tired, or weak.
  • Headache.
  • Upset stomach or throwing up.
  • Back pain.
  • Weight gain.
  • Stomach pain.
  • Bruising.

These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.

You may report side effects to the FDA at 1-800-332-1088. You may also report side effects at

If OVERDOSE is suspected:

If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

How do I store and/or throw out Fycompa?

  • Store at room temperature.
  • Store in a dry place. Do not store in a bathroom.
  • Do not freeze.
  • Throw away any part not used 90 days after opening.
  • Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
  • Throw away unused or expired drugs. Do not flush down a toilet or pour down a drain unless you are told to do so. Check with your pharmacist if you have questions about the best way to throw out drugs. There may be drug take-back programs in your area.

Consumer information use

  • If your symptoms or health problems do not get better or if they become worse, call your doctor.
  • Do not share your drugs with others and do not take anyone else's drugs.
  • This medicine comes with an extra patient fact sheet called a Medication Guide. Read it with care. Read it again each time Fycompa (perampanel oral suspension) is refilled. If you have any questions about Fycompa (perampanel oral suspension), please talk with the doctor, pharmacist, or other health care provider.
  • If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.