Generic Name: Fosaprepitant (fos a PRE pi tant)
Brand Name: Emend
Medically reviewed on July 4, 2018
Uses of Fosaprepitant:
- It is used to prevent upset stomach and throwing up from chemo.
- It may be given to you for other reasons. Talk with the doctor.
What do I need to tell my doctor BEFORE I take Fosaprepitant?
- If you have an allergy to fosaprepitant, aprepitant, polysorbate 80, or any other part of fosaprepitant.
- If you are allergic to any drugs like this one, any other drugs, foods, or other substances. Tell your doctor about the allergy and what signs you had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
- If you take any drugs (prescription or OTC, natural products, vitamins) that must not be taken with fosaprepitant, like certain drugs that are used for HIV, infections, or seizures. There are many drugs that must not be taken with fosaprepitant.
This is not a list of all drugs or health problems that interact with fosaprepitant.
Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take fosaprepitant with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.
What are some things I need to know or do while I take Fosaprepitant?
- Tell all of your health care providers that you take fosaprepitant. This includes your doctors, nurses, pharmacists, and dentists.
- Allergic reactions have happened with fosaprepitant. You will be watched closely while you receive fosaprepitant and for some time after your dose. Talk with your doctor.
- If you are taking warfarin, talk with your doctor. You may need to have your blood work checked more closely while you are taking it with fosaprepitant.
- Birth control pills and other hormone-based birth control may not work as well to prevent pregnancy. Use some other kind of birth control also, like a condom, when taking fosaprepitant and for 1 month after care ends.
- Tell your doctor if you are pregnant or plan on getting pregnant. You will need to talk about the benefits and risks of using fosaprepitant while you are pregnant.
- Tell your doctor if you are breast-feeding. You will need to talk about any risks to your baby.
How is this medicine (Fosaprepitant) best taken?
Use fosaprepitant as ordered by your doctor. Read all information given to you. Follow all instructions closely.
- It is given as an infusion into a vein over a period of time.
What do I do if I miss a dose?
- Call your doctor to find out what to do.
See also: Dosage Information (in more detail)
What are some side effects that I need to call my doctor about right away?
WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:
- Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
- Signs of a urinary tract infection (UTI) like blood in the urine, burning or pain when passing urine, feeling the need to pass urine often or right away, fever, lower stomach pain, or pelvic pain.
- Dizziness or passing out.
- A fast heartbeat.
- A heartbeat that does not feel normal.
- Pain and irritation where fosaprepitant goes into the body.
- A burning, numbness, or tingling feeling that is not normal.
- Feeling very tired or weak.
- A very bad skin reaction (Stevens-Johnson syndrome/toxic epidermal necrolysis) may happen. It can cause very bad health problems that may not go away, and sometimes death. Get medical help right away if you have signs like red, swollen, blistered, or peeling skin (with or without fever); red or irritated eyes; or sores in your mouth, throat, nose, or eyes.
- Low white blood cell counts have rarely happened with fosaprepitant. This may lead to a higher chance of getting an infection. Tell your doctor if you have ever had a low white blood cell count. Call your doctor right away if you have signs of infection like fever, chills, or sore throat.
- This medicine may cause tissue damage if the drug leaks from the vein. Tell your nurse if you have any redness, burning, pain, swelling, blisters, skin sores, or leaking of fluid where the drug is going into your body.
What are some other side effects of Fosaprepitant?
All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:
These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.
You may report side effects to the FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.
See also: Side effects (in more detail)
If OVERDOSE is suspected:
If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
How do I store and/or throw out Fosaprepitant?
- If you need to store fosaprepitant at home, talk with your doctor, nurse, or pharmacist about how to store it.
Consumer information use
- If your symptoms or health problems do not get better or if they become worse, call your doctor.
- Do not share your drugs with others and do not take anyone else's drugs.
- Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
- Talk with the doctor before starting any new drug, including prescription or OTC, natural products, or vitamins.
- Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
- Throw away unused or expired drugs. Do not flush down a toilet or pour down a drain unless you are told to do so. Check with your pharmacist if you have questions about the best way to throw out drugs. There may be drug take-back programs in your area.
- Some drugs may have another patient information leaflet. Check with your pharmacist. If you have any questions about fosaprepitant, please talk with your doctor, nurse, pharmacist, or other health care provider.
- If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
More about fosaprepitant
- Fosaprepitant Side Effects
- During Pregnancy
- Dosage Information
- Drug Interactions
- En Español
- 1 Review
- Drug class: NK1 receptor antagonists
Other brands: Emend for Injection