Generic Name: alendronate (a-LEN-droe-nate)
Brand Name: Fosamax
Fosamax solution is used for:
Treating and preventing osteoporosis in certain patients. It may also be used for other conditions as determined by your doctor.
Fosamax solution is a bisphosphonate. It works by slowing bone loss.
Do NOT use Fosamax solution if:
- you are allergic to any ingredient in Fosamax solution
- you have certain esophagus problems (eg, narrowing, blockage)
- you are unable to stand or sit upright for at least 30 minutes
- you have low blood calcium levels or severe kidney problems
- you are at risk of aspiration (inhaling foreign matter into the airway or lungs)
Contact your doctor or health care provider right away if any of these apply to you.
Before using Fosamax solution:
Some medical conditions may interact with Fosamax solution. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
- if you are pregnant, planning to become pregnant, or are breast-feeding
- if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
- if you have allergies to medicines, foods, or other substances
- if you have a history of stomach or bowel problems (eg, inflammation, ulcer), esophagus problems (eg, heartburn, reflux disease, severe irritation), or kidney problems, or if you have difficult or painful swallowing
- if you are bedridden or have a history of aspiration
- if you have low blood vitamin D levels, cancer, anemia, asthma, blood clotting problems, an infection, calcium metabolism problems, or nutrient absorption problems (eg, malabsorption syndrome), or you are unable to take calcium or vitamin D supplements
- if you have poor dental hygiene or other dental problems, or you will be having a dental procedure (eg, tooth extraction)
- if you smoke or drink alcohol
- if you have had or will be having chemotherapy or radiation treatment
- if you have a mental disorder or other condition that may decrease your ability to follow the dosing instructions for Fosamax solution
- if you are taking any medicines that can cause jaw bone problems. There are many medicines that can do this. Ask your doctor or pharmacist if you are not sure.
Some MEDICINES MAY INTERACT with Fosamax solution. Tell your health care provider if you are taking any other medicines, especially any of the following:
- Aspirin or nonsteroidal anti-inflammatory drugs (NSAIDs) (eg, ibuprofen) because the risk of side effects, such as esophagus or stomach irritation, may be increased
- Corticosteroids (eg, prednisone) or angiogenesis inhibitors (eg, bevacizumab) because the risk of jawbone problems may be increased
This may not be a complete list of all interactions that may occur. Ask your health care provider if Fosamax solution may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.
How to use Fosamax solution:
Use Fosamax solution as directed by your doctor. Check the label on the medicine for exact dosing instructions.
- Fosamax solution comes with an extra patient information sheet called a Medication Guide. Read it carefully. Read it again each time you get Fosamax solution refilled.
- Be sure you understand how much of Fosamax solution to take for your dose.
- Take Fosamax solution by mouth on an empty stomach in the morning at least 30 minutes before your first food, drink, or other medicine of the day. Do NOT take Fosamax solution at bedtime or before you get out of bed in the morning.
- Drink at least 2 oz (1/4 cup) of plain water after you take Fosamax solution. Do not take Fosamax solution with mineral water, coffee, tea, or juice. Do not lie down for 30 minutes after taking Fosamax solution and until you eat your first food of the day.
- Fosamax solution is usually taken 1 time each week. Be sure you understand how to take Fosamax solution. Contact your doctor or pharmacist if you have any questions.
- Continue to take Fosamax solution even if you feel well. Do not miss any doses.
- If you miss a dose of Fosamax solution, do not take it later in the day. Take it the morning after you remember, and then go back to your regular dosing schedule. Do not take 2 doses within the same day.
Ask your health care provider any questions you may have about how to use Fosamax solution.
Important safety information:
- Tell your doctor or dentist that you take Fosamax solution before you receive any medical or dental care, emergency care, or surgery.
- Fosamax solution may cause dizziness. This effect may be worse if you take it with alcohol or certain medicines. Use Fosamax solution with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
- Talk with your doctor before you drink alcohol, smoke, or use other tobacco products while taking Fosamax solution.
- Follow the diet and exercise program given to you by your health care provider. Talk to your doctor about whether you should take a calcium and vitamin D supplement while you use Fosamax solution.
- Talk to your doctor about the use of weight-bearing exercises to help prevent weak bones.
- Certain fractures of the thigh bone (femur) have been reported in patients using bisphosphonates. It is unknown if bisphosphonates contributed to the fractures. Contact your doctor right away if you experience hip, thigh, or groin pain. Discuss any questions or concerns with your doctor.
- Fosamax solution may cause jawbone problems in some patients. Your risk may be greater the longer you take Fosamax solution or if you have cancer, poor dental hygiene, ill-fitting dentures, or certain other conditions (eg, anemia, blood clotting problems, dental problems, infection). Your risk may also be greater if you have certain dental procedures or you use certain medicines or therapies (eg, chemotherapy, corticosteroids, radiation). Talk to your doctor about having a dental exam before you start to use Fosamax solution. Ask your doctor any questions you may have about dental treatment while you use Fosamax solution.
- Proper dental care is important while you are taking Fosamax solution. Brush and floss your teeth and visit the dentist regularly.
- Fosamax solution may cause you to become sunburned more easily. Avoid the sun, sunlamps, or tanning booths until you know how you react to Fosamax solution. Use a sunscreen or wear protective clothing if you must be outside for more than a short time.
- Certain dental procedures should be avoided if possible while you are using Fosamax solution. Tell your doctor or dentist that you take Fosamax solution before you receive any medical or dental care, emergency care, or surgery.
- Worsening of asthma has been reported in patients taking medicines like this one. Discuss any questions or concerns with your doctor.
- Lab tests, including bone density and blood calcium levels, may be performed while you use Fosamax solution. These tests may be used to monitor your condition or check for side effects. Your doctor may also want to evaluate you periodically while you take Fosamax solution to assess the need to continue treatment. Be sure to keep all doctor and lab appointments.
- Fosamax solution should not be used in CHILDREN; safety and effectiveness in children have not been confirmed.
- PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Fosamax solution while you are pregnant. It is not known if this medicine is found in breast milk. If you are or will be breast-feeding while you use Fosamax solution, check with your doctor. Discuss any possible risks to your baby.
Possible side effects of Fosamax solution:
All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:
Seek medical attention right away if any of these SEVERE side effects occur:
Constipation; diarrhea; dizziness; feeling bloated or full; flu-like symptoms at the start of treatment; gas; headache; mild back, muscle, or joint pain; mild stomach pain or upset; nausea; taste changes; vomiting.
Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, throat, or tongue); black, tarry, or bloody stools; chest pain; coughing or vomiting blood; difficult or painful swallowing; mouth sores; new, worsening, or persistent heartburn; red, swollen, blistered, or peeling skin; severe bone, muscle, or joint pain (especially in the hip, groin, or thigh); severe or persistent sore throat or stomach pain; swelling of the hands, legs, or joints; swelling or pain in the jaw; symptoms of low blood calcium (eg, spasms, twitches, or cramps in your muscles; numbness or tingling in your fingers, toes, or around your mouth).
This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.
If OVERDOSE is suspected:
Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Do not lie down. Do not try to vomit.Proper storage of Fosamax solution:
Store Fosamax solution at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Do not freeze. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Fosamax solution out of the reach of children and away from pets.
- If you have any questions about Fosamax solution, please talk with your doctor, pharmacist, or other health care provider.
- Fosamax solution is to be used only by the patient for whom it is prescribed. Do not share it with other people.
- If your symptoms do not improve or if they become worse, check with your doctor.
- Check with your pharmacist about how to dispose of unused medicine.
This information should not be used to decide whether or not to take Fosamax solution or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about Fosamax solution. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to Fosamax solution. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your health care provider for complete information about the risks and benefits of using Fosamax solution.
Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.
More about Fosamax (alendronate)
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