Factor VIIa (Recombinant)
Generic Name: Factor VIIa (Recombinant) (FAK ter SEV en aye ree KOM be nant)
Brand Name: NovoSeven RT
Medically reviewed on Sep 5, 2018
- Blood clots have happened with factor VIIa (recombinant). Sometimes, these blood clots have been deadly. Call your doctor right away if you have chest, arm, back, neck, or jaw pain or pressure; coughing up blood; numbness or weakness on 1 side of your body, trouble speaking or thinking, change in balance, or change in eyesight; shortness of breath; or swelling, warmth, or pain in the leg or arm.
Uses of Factor VIIa:
- It is used to treat or prevent bleeding.
What do I need to tell my doctor BEFORE I take Factor VIIa?
- If you have an allergy to factor VIIa (recombinant) or any part of factor VIIa (recombinant).
- If you are allergic to cows, hamsters, or mice.
- If you are allergic to any drugs like this one, any other drugs, foods, or other substances. Tell your doctor about the allergy and what signs you had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
This medicine may interact with other drugs or health problems.
Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take factor VIIa (recombinant) with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.
What are some things I need to know or do while I take Factor VIIa?
- Tell all of your health care providers that you take factor VIIa (recombinant). This includes your doctors, nurses, pharmacists, and dentists.
- Allergic side effects may rarely happen.
- Have blood work checked as you have been told by the doctor. Talk with the doctor.
- Call the doctor right away if the normal dose does not work as well.
- If you are 65 or older, use factor VIIa (recombinant) with care. You could have more side effects.
- Use with care in newborns. Talk with the doctor.
- Tell your doctor if you are pregnant or plan on getting pregnant. You will need to talk about the benefits and risks of using factor VIIa (recombinant) while you are pregnant.
- Tell your doctor if you are breast-feeding. You will need to talk about any risks to your baby.
How is this medicine (Factor VIIa) best taken?
Use factor VIIa (recombinant) as ordered by your doctor. Read all information given to you. Follow all instructions closely.
- It is given as a shot into a vein.
- If you will be giving yourself the shot, your doctor or nurse will teach you how to give the shot.
- Follow how to use as you have been told by the doctor or read the package insert.
- Wash your hands before and after use.
- If stored in a refrigerator, let factor VIIa (recombinant) come to room temperature before mixing. Do not heat factor VIIa (recombinant).
- You can bring factor VIIa (recombinant) to room temperature by holding it in your hands until it feels as warm as your hands.
- This medicine needs to be mixed before use. Follow how to mix as you were told by the doctor.
- Do not shake.
- Use within 3 hours of making.
- Do not draw into a syringe and store for future use.
- Do not mix with any other liquid drugs.
- Do not use if the solution is cloudy, leaking, or has particles.
- Do not use if solution changes color.
- Throw away any part not used after use.
- Throw away needles in a needle/sharp disposal box. Do not reuse needles or other items. When the box is full, follow all local rules for getting rid of it. Talk with a doctor or pharmacist if you have any questions.
What do I do if I miss a dose?
- Call your doctor to find out what to do.
See also: Dosage Information (in more detail)
What are some side effects that I need to call my doctor about right away?
WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:
- Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
- Signs of high or low blood pressure like very bad headache or dizziness, passing out, change in eyesight.
- Belly pain.
- Swelling of belly.
What are some other side effects of Factor VIIa?
All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if you have any side effects that bother you or do not go away.
These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.
You may report side effects to the FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.
See also: Side effects (in more detail)
If OVERDOSE is suspected:
If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
How do I store and/or throw out Factor VIIa?
- If factor VIIa (recombinant) is given at home, store unopened containers at room temperature or in the refrigerator. Do not freeze.
- Protect from light.
- Do not use if factor VIIa (recombinant) is out of date.
- Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
- Throw away unused or expired drugs. Do not flush down a toilet or pour down a drain unless you are told to do so. Check with your pharmacist if you have questions about the best way to throw out drugs. There may be drug take-back programs in your area.
Consumer information use
- If your symptoms or health problems do not get better or if they become worse, call your doctor.
- Do not share your drugs with others and do not take anyone else's drugs.
- Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
- Talk with the doctor before starting any new drug, including prescription or OTC, natural products, or vitamins.
- Some drugs may have another patient information leaflet. Check with your pharmacist. If you have any questions about factor VIIa (recombinant), please talk with your doctor, nurse, pharmacist, or other health care provider.
- If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
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- Drug class: miscellaneous coagulation modifiers
Other brands: NovoSeven RT