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Generic Name: Agalsidase Beta (aye GAL si days BAY ta)
Brand Name: Fabrazyme

Medically reviewed by Last updated on Oct 3, 2020.

Uses of Fabrazyme:

  • It is used to treat Fabry disease.

What do I need to tell my doctor BEFORE I take Fabrazyme?

  • If you have an allergy to agalsidase beta or any other part of Fabrazyme (agalsidase beta).
  • If you are allergic to Fabrazyme (agalsidase beta); any part of Fabrazyme (agalsidase beta); or any other drugs, foods, or substances. Tell your doctor about the allergy and what signs you had.

This medicine may interact with other drugs or health problems.

Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take Fabrazyme (agalsidase beta) with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.

What are some things I need to know or do while I take Fabrazyme?

  • Tell all of your health care providers that you take Fabrazyme (agalsidase beta). This includes your doctors, nurses, pharmacists, and dentists.
  • Allergic reactions have happened with Fabrazyme (agalsidase beta). Rarely, some reactions can be very bad or life-threatening. Talk with the doctor.
  • Other drugs may be given before Fabrazyme (agalsidase beta) to help avoid side effects.
  • Tell your doctor if you are pregnant or plan on getting pregnant. You will need to talk about the benefits and risks of using Fabrazyme (agalsidase beta) while you are pregnant.
  • Tell your doctor if you are breast-feeding. You will need to talk about any risks to your baby.

How is this medicine (Fabrazyme) best taken?

Use Fabrazyme (agalsidase beta) as ordered by your doctor. Read all information given to you. Follow all instructions closely.

  • It is given as an infusion into a vein over a period of time.

What do I do if I miss a dose?

  • Call your doctor to find out what to do.

What are some side effects that I need to call my doctor about right away?

WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:

  • Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
  • Change in hearing.
  • Hearing loss.
  • Ringing in ears.
  • Low mood (depression).
  • Dizziness or passing out.
  • Shortness of breath.
  • Some patients have severe side effects during the infusion. Tell your doctor if you have a burning, numbness, or tingling feeling that is not normal; chest pain; fast or slow heartbeat; feeling hot or cold; feeling sleepy; fever or chills; flushing; headache; diarrhea; muscle pain or weakness; pain in the arms or legs; pale skin; stomach pain; stuffy nose; swelling; tiredness; upset stomach or throwing up; or any other bad effects during the infusion.

What are some other side effects of Fabrazyme?

All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:

These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.

You may report side effects to the FDA at 1-800-332-1088. You may also report side effects at

If OVERDOSE is suspected:

If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

How do I store and/or throw out Fabrazyme?

  • If you need to store Fabrazyme (agalsidase beta) at home, talk with your doctor, nurse, or pharmacist about how to store it.

Consumer information use

  • If your symptoms or health problems do not get better or if they become worse, call your doctor.
  • Do not share your drugs with others and do not take anyone else's drugs.
  • Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
  • Throw away unused or expired drugs. Do not flush down a toilet or pour down a drain unless you are told to do so. Check with your pharmacist if you have questions about the best way to throw out drugs. There may be drug take-back programs in your area.
  • Some drugs may have another patient information leaflet. Check with your pharmacist. If you have any questions about Fabrazyme (agalsidase beta), please talk with your doctor, nurse, pharmacist, or other health care provider.
  • If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.