Generic Name: dextromethorphan/guaifenesin/pseudoephedrine (DEX-troe-meth-OR-fan/gwye-FEN-e-sin/SOO-doe-e-FED-rin)
Brand Name: Examples include Entre-Cough and Z-COF 12.
Entre-Cough suspension is used for:
Relieving congestion, cough, and throat and airway irritation due to colds, flu, or hay fever. It may also be used for other conditions as determined by your doctor.
Entre-Cough suspension is a decongestant, cough suppressant, and expectorant combination. It works by constricting blood vessels, reducing swelling in the nasal passages, and loosening mucus and lung secretions in the chest, making coughs more productive. The cough suppressant works in the brain to help decrease the cough reflex.
Do NOT use Entre-Cough suspension if:
- you are allergic to any ingredient in Entre-Cough suspension
- you have severe high blood pressure, rapid heartbeat, or other severe heart problems (eg, heart blood vessel disease)
- you have taken furazolidone or a monoamine oxidase inhibitor (MAOI) (eg, phenelzine) within the last 14 days
Contact your doctor or health care provider right away if any of these apply to you.
Before using Entre-Cough suspension:
Some medical conditions may interact with Entre-Cough suspension. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
- if you are pregnant, planning to become pregnant, or are breast-feeding
- if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
- if you have allergies to medicines, foods, or other substances
- if you have a history of glaucoma, enlarged prostate gland or other prostate problems, heart problems, diabetes, high blood pressure, blood vessel problems, adrenal gland problems, an overactive thyroid, seizures, or stroke
- if you have a chronic cough, chronic obstructive pulmonary disease (COPD), or other lung problems (eg, asthma, chronic bronchitis, emphysema), or if your cough produces large amounts of mucus
Some MEDICINES MAY INTERACT with Entre-Cough suspension. Tell your health care provider if you are taking any other medicines, especially any of the following:
- Beta-blockers (eg, propranolol), catechol-O-methyltransferase (COMT) inhibitors (eg, tolcapone), furazolidone, indomethacin, MAOIs (eg, phenelzine), or tricyclic antidepressants (eg, amitriptyline) because they may increase the risk Entre-Cough suspension's side effects
- Digoxin or droxidopa because the risk of irregular heartbeat or heart attack may be increased
- Bromocriptine because the risk of its side effects may be increased by Entre-Cough suspension
- Guanadrel, guanethidine, mecamylamine, methyldopa, or reserpine because their effectiveness may be decreased by Entre-Cough suspension
This may not be a complete list of all interactions that may occur. Ask your health care provider if Entre-Cough suspension may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.
How to use Entre-Cough suspension:
Use Entre-Cough suspension as directed by your doctor. Check the label on the medicine for exact dosing instructions.
- Take Entre-Cough suspension by mouth with or without food.
- Shake well before each use.
- Drink plenty of water while taking Entre-Cough suspension.
- Use a measuring device marked for medicine dosing. Ask your pharmacist for help if you are unsure of how to measure your dose.
- If you miss a dose of Entre-Cough suspension, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.
Ask your health care provider any questions you may have about how to use Entre-Cough suspension.
Important safety information:
- Entre-Cough suspension may cause dizziness or drowsiness. These effects may be worse if you take it with alcohol or certain medicines. Use Entre-Cough suspension with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
- Do not take appetite suppressants while you are taking Entre-Cough suspension without checking with your doctor.
- Entre-Cough suspension has pseudoephedrine and dextromethorphan in it. Before you start any new medicine, check the label to see if it has pseudoephedrine or dextromethorphan in it too. If it does or if you are not sure, check with your doctor or pharmacist.
- Do NOT exceed the recommended dose or take Entre-Cough suspension for longer than prescribed without checking with your doctor.
- If your symptoms do not improve within 5 to 7 days or if they become worse, check with your doctor.
- Do not use Entre-Cough suspension for a cough with a lot of mucous. Do not use it for a long-term cough (eg, caused by asthma, emphysema, smoking). However, you may use it for these conditions if your doctor tells you to.
- Entre-Cough suspension may interfere with certain lab tests. Be sure that your doctor and lab personnel know you are taking Entre-Cough suspension.
- Tell your doctor or dentist that you take Entre-Cough suspension before you receive any medical or dental care, emergency care, or surgery.
- Use Entre-Cough suspension with caution in the ELDERLY; they may be more sensitive to its effects.
- Caution is advised when using Entre-Cough suspension in CHILDREN; they may be more sensitive to its effects.
- PREGNANCY and BREAST-FEEDING: If you become pregnant while taking Entre-Cough suspension, contact your doctor. You will need to discuss the benefits and risks of using Entre-Cough suspension while you are pregnant. It is not known if this medicine is found in breast milk. Do not breast-feed while taking Entre-Cough suspension.
Possible side effects of Entre-Cough suspension:
All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:
Seek medical attention right away if any of these SEVERE side effects occur:
Diarrhea; dizziness; drowsiness; excitability; headache; irritability; nausea; stomach upset; trouble sleeping.
Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); difficulty urinating; fast, slow, or irregular heartbeat; fever; hallucinations; seizures; severe or persistent dizziness, lightheadedness, or headache; tremor.
This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.
If OVERDOSE is suspected:
Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include blurred vision; confusion; hallucinations; seizures; severe dizziness, lightheadedness, or headache; severe drowsiness; unusually fast, slow, or irregular heartbeat; vomiting.Proper storage of Entre-Cough suspension:
Store Entre-Cough suspension at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Entre-Cough suspension out of the reach of children and away from pets.
- If you have any questions about Entre-Cough suspension, please talk with your doctor, pharmacist, or other health care provider.
- Entre-Cough suspension is to be used only by the patient for whom it is prescribed. Do not share it with other people.
- If your symptoms do not improve or if they become worse, check with your doctor.
- Check with your pharmacist about how to dispose of unused medicine.
This information should not be used to decide whether or not to take Entre-Cough suspension or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about Entre-Cough suspension. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to Entre-Cough suspension. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using Entre-Cough suspension.
Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.
More about Entre-Cough (dextromethorphan / guaifenesin / pseudoephedrine)
- Side Effects
- During Pregnancy
- Dosage Information
- Drug Interactions
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- Drug class: upper respiratory combinations