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Dextromethorphan/ guaifenesin/ pseudoephedrine liquid

Generic Name: dextromethorphan/guaifenesin/pseudoephedrine (DEX-troe-meth-OR-fan/gwye-FEN-e-sin/SOO-doe-e-FED-rin)
Brand Name: Examples include Poly-Vent DM and Tusnel-DM Pediatric Drops

Dextromethorphan/ guaifenesin/ pseudoephedrine liquid is used for:

Relieving congestion, cough, and throat and airway irritation due to colds, flu, or hay fever. It may also be used for other conditions as determined by your doctor.

Dextromethorphan/guaifenesin/pseudoephedrine liquid is a decongestant, cough suppressant, and expectorant combination. The decongestant works by constricting blood vessels and reducing swelling in the nasal passages. The expectorant works by loosening mucus and lung secretions in the chest, making coughs more productive. The cough suppressant works in the brain to help decrease the cough reflex to reduce a dry cough.

Do NOT use dextromethorphan/ guaifenesin/ pseudoephedrine liquid if:

  • you are allergic to any ingredient in dextromethorphan/guaifenesin/pseudoephedrine liquid
  • you have severe or uncontrolled high blood pressure, rapid heartbeat, or other severe heart problems (eg, heart blood vessel disease)
  • you take droxidopa or have taken furazolidone or a monoamine oxidase inhibitor (MAOI) (eg, phenelzine) within the last 14 days

Contact your doctor or health care provider right away if any of these apply to you.

Before using dextromethorphan/ guaifenesin/ pseudoephedrine liquid:

Some medical conditions may interact with dextromethorphan/guaifenesin/pseudoephedrine liquid. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have a history of glaucoma or increased pressure in the eye, trouble urinating, enlarged prostate gland or other prostate problems, heart problems (eg, fast, slow, or irregular heartbeat; heart disease), diabetes, high blood pressure, blood vessel problems, adrenal gland problems (eg, pheochromocytoma), mental or mood problems (eg, depression), trouble sleeping, thyroid problems, seizures, or stroke
  • if you have a history of asthma, chronic obstructive pulmonary disease (COPD), or other lung or breathing problems (eg, chronic bronchitis, emphysema, sleep apnea), chronic cough, or if your cough produces large amounts of mucus
  • if you are in poor health or are very overweight
  • if you take medicine for high blood pressure or depression

Some MEDICINES MAY INTERACT with dextromethorphan/guaifenesin/pseudoephedrine liquid. Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Abiraterone, beta-blockers (eg, propranolol), catechol-O-methyltransferase (COMT) inhibitors (eg, tolcapone), furazolidone, linezolid, MAOIs (eg, phenelzine), selective serotonin reuptake inhibitors (SSRIs) (eg, citalopram, fluoxetine), tricyclic antidepressants (eg, amitriptyline), or urinary alkalinizers (eg, sodium bicarbonate) because they may increase the risk of dextromethorphan/guaifenesin/pseudoephedrine liquid's side effects
  • Digoxin or droxidopa because the risk of irregular heartbeat or heart attack may be increased
  • Bromocriptine because the risk of its side effects may be increased by dextromethorphan/guaifenesin/pseudoephedrine liquid
  • Guanadrel, guanethidine, mecamylamine, methyldopa, or reserpine because their effectiveness may be decreased by dextromethorphan/guaifenesin/pseudoephedrine liquid

This may not be a complete list of all interactions that may occur. Ask your health care provider if dextromethorphan/guaifenesin/pseudoephedrine liquid may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use dextromethorphan/ guaifenesin/ pseudoephedrine liquid:

Use dextromethorphan/guaifenesin/pseudoephedrine liquid as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Take dextromethorphan/guaifenesin/pseudoephedrine liquid by mouth with or without food. If stomach upset occurs, take with food to reduce stomach irritation.
  • Drink plenty of water while taking dextromethorphan/guaifenesin/pseudoephedrine liquid.
  • Use a measuring device marked for medicine dosing. If dextromethorphan/guaifenesin/pseudoephedrine liquid comes with a dropper or measuring device, use it to measure your dose. Ask your pharmacist for help if you are unsure of how to measure your dose.
  • If you miss a dose of dextromethorphan/guaifenesin/pseudoephedrine liquid and you are taking it regularly, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use dextromethorphan/guaifenesin/pseudoephedrine liquid.

Important safety information:

  • Dextromethorphan/guaifenesin/pseudoephedrine liquid may cause dizziness or drowsiness. These effects may be worse if you take it with alcohol or certain medicines. Use dextromethorphan/guaifenesin/pseudoephedrine liquid with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
  • Check with your doctor before you drink alcohol or use medicines that may cause drowsiness (eg, sleep aids, muscle relaxers) while you are using dextromethorphan/guaifenesin/pseudoephedrine liquid; it may add to their effects. Ask your pharmacist if you have questions about which medicines may cause drowsiness.
  • Do not take appetite suppressants while you are taking dextromethorphan/guaifenesin/pseudoephedrine liquid without checking with your doctor.
  • Before you start any new medicine, check the label to see if it has a decongestant, a cough suppressant, or an expectorant in it too. If it does or if you are not sure, check with your doctor or pharmacist.
  • Some of these products contain phenylalanine. If you must have a diet that is low in phenylalanine, ask your pharmacist if it is in your product.
  • Do NOT take more than the recommended dose or use for longer than prescribed without checking with your doctor.
  • If your symptoms do not improve within 5 to 7 days, if they get worse, or if they occur along with a fever, rash, or headache, check with your doctor.
  • Do not use dextromethorphan/guaifenesin/pseudoephedrine liquid for a cough with a lot of mucus. Do not use it for a long-term cough (eg, caused by asthma, emphysema, smoking). However, you may use it for these conditions if your doctor tells you to.
  • Dextromethorphan/guaifenesin/pseudoephedrine liquid may interfere with certain lab tests. Be sure that your doctor and lab personnel know you are taking dextromethorphan/guaifenesin/pseudoephedrine liquid.
  • Tell your doctor or dentist that you take dextromethorphan/guaifenesin/pseudoephedrine liquid before you receive any medical or dental care, emergency care, or surgery.
  • Use dextromethorphan/guaifenesin/pseudoephedrine liquid with caution in the ELDERLY; they may be more sensitive to its effects, especially confusion, dizziness, drowsiness, dry mouth, excitability, low blood pressure, and trouble urinating.
  • Caution is advised when using dextromethorphan/guaifenesin/pseudoephedrine liquid in CHILDREN; they may be more sensitive to its effects.
  • Different brands of dextromethorphan/guaifenesin/pseudoephedrine liquid may have different dosing instructions for CHILDREN. Follow the dosing instructions on the package labeling. If your doctor has given you instructions, follow those. If you are unsure of the dose to give a child, check with your doctor or pharmacist.
  • PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using dextromethorphan/guaifenesin/pseudoephedrine liquid while you are pregnant. It is not known if this medicine is found in breast milk. Do not breast-feed while taking dextromethorphan/guaifenesin/pseudoephedrine liquid.

Possible side effects of dextromethorphan/ guaifenesin/ pseudoephedrine liquid:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Diarrhea; dizziness; drowsiness; excitability; headache; irritability; nausea; stomach upset; trouble sleeping.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); confusion; difficulty urinating or inability to urinate; fast, slow, or irregular heartbeat; fever, chills, or persistent sore throat; hallucinations; mental or mood changes (eg, anxiety, nervousness); persistent trouble sleeping; restlessness; seizures; severe or persistent dizziness, drowsiness, light-headedness, or headache; tremor; unusually pale skin.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include blurred vision; confusion; difficulty urinating; fast or shallow breathing; hallucinations; restlessness; seizures; severe dizziness, light-headedness, or headache; severe drowsiness; tremor; unusually fast, slow, or irregular heartbeat; unusually pale skin; vomiting.

Proper storage of dextromethorphan/guaifenesin/pseudoephedrine liquid:

Store dextromethorphan/guaifenesin/pseudoephedrine liquid at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep dextromethorphan/guaifenesin/pseudoephedrine liquid out of the reach of children and away from pets.

General information:

  • If you have any questions about dextromethorphan/guaifenesin/pseudoephedrine liquid, please talk with your doctor, pharmacist, or other health care provider.
  • Dextromethorphan/guaifenesin/pseudoephedrine liquid is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.
  • Check with your pharmacist about how to dispose of unused medicine.

This information should not be used to decide whether or not to take dextromethorphan/guaifenesin/pseudoephedrine liquid or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about dextromethorphan/guaifenesin/pseudoephedrine liquid. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to dextromethorphan/guaifenesin/pseudoephedrine liquid. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using dextromethorphan/guaifenesin/pseudoephedrine liquid.

Review Date: November 3, 2016

Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.

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