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Degarelix acetate

Generic Name: degarelix acetate (DEG-a-REL-ix)
Brand Name: Generic only. No brands available.

Degarelix acetate is used for:

Treating advanced prostate cancer.

Degarelix acetate is a gonadotropin-releasing hormone (GnRH) receptor antagonist. It works by decreasing the amount of testosterone in the body, which the tumor needs to grow.

Do NOT use degarelix acetate if:

  • you are allergic to any ingredient in degarelix acetate
  • you are or may become pregnant

Contact your doctor or health care provider right away if any of these apply to you.

Before using degarelix acetate:

Some medical conditions may interact with degarelix acetate. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have heart problems (eg, heart failure), an irregular heartbeat (eg, QT prolongation), or electrolyte problems (eg, low blood magnesium or potassium levels)
  • if you have liver problems, kidney problems, or bone problems (eg, weak bones, osteoporosis)
  • if you are taking any medicines that can cause a certain type of irregular heartbeat (prolonged QT interval). There are many medicines that can do this. Ask your doctor or pharmacist if you are not sure.

Some MEDICINES MAY INTERACT with degarelix acetate. Tell your health care provider if you are taking any other medicines.

Ask your health care provider if degarelix acetate may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use degarelix acetate:

Use degarelix acetate as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • An extra patient leaflet is available with degarelix acetate. Talk to your pharmacist if you have questions about this information
  • Degarelix acetate is given as an injection at your doctor's office, hospital, or clinic. Contact your health care provider if you have any questions.
  • Do not use degarelix acetate in an area that will be exposed to pressure (eg, near the waistband, belt, or other tight clothing)
  • If you miss a dose of degarelix acetate, contact your doctor right away.

Ask your health care provider any questions you may have about how to use degarelix acetate.

Important safety information:

  • Degarelix acetate may cause dizziness. This effect may be worse if you take it with alcohol or certain medicines. Use degarelix acetate with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
  • Degarelix acetate may interfere with certain lab tests, including tests for male fertility. Be sure your doctor and lab personnel know you are using degarelix acetate.
  • You may need to have an electrocardiogram (ECG) checked before starting degarelix acetate and while taking it. Discuss any questions or concerns with your doctor.
  • Lab tests, including liver function and prostate-specific antigen (PSA), may be performed while you use degarelix acetate. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
  • Degarelix acetate should not be used in CHILDREN; safety and effectiveness in children have not been confirmed.
  • PREGNANCY and BREAST-FEEDING: Degarelix acetate is not approved for use in women. Do not use degarelix acetate if you are pregnant. It has been shown to cause harm to the fetus. Avoid becoming pregnant while you are taking it. If you think you may be pregnant, contact your doctor right away. It is not known if this medicine is found in breast milk. Do not breast-feed while taking degarelix acetate.

Possible side effects of degarelix acetate:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Back or joint pain; chills; constipation; decreased sexual desire or ability; dizziness; flushing; hot flashes; pain, redness, swelling, or lumps at the injection site; tiredness; weight loss or gain.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing or swallowing; tightness in the chest; swelling of the mouth, face, lips, throat, or tongue; unusual hoarseness); dark urine; fainting; fast or irregular heartbeat; fever; frequent or painful urination; severe or persistent bone pain; severe or persistent dizziness or headache; yellowing of the skin or eyes.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately.

Proper storage of degarelix acetate:

Degarelix acetate is handled and stored by a health care provider. You will not store it at home. Keep all medicines out of the reach of children and away from pets.

General information:

  • If you have any questions about degarelix acetate, please talk with your doctor, pharmacist, or other health care provider.
  • Degarelix acetate is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.
  • Check with your pharmacist about how to dispose of unused medicine.

This information should not be used to decide whether or not to take degarelix acetate or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about degarelix acetate. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to degarelix acetate. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your health care provider for complete information about the risks and benefits of using degarelix acetate.

Review Date: November 3, 2016

Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.

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