Daunorubicin and Cytarabine (Liposomal)
Medically reviewed by Drugs.com. Last updated on Mar 12, 2022.
Uses of Daunorubicin and Cytarabine:
- It is used to treat a type of leukemia.
What do I need to tell my doctor BEFORE I take Daunorubicin and Cytarabine?
- If you are allergic to daunorubicin and cytarabine (liposomal); any part of daunorubicin and cytarabine (liposomal); or any other drugs, foods, or substances. Tell your doctor about the allergy and what signs you had.
- If you have heart problems like heart failure.
- If you have taken any drugs like this one.
- If you are breast-feeding. Do not breast-feed while you take daunorubicin and cytarabine (liposomal) and for 2 weeks after your last dose.
This is not a list of all drugs or health problems that interact with daunorubicin and cytarabine (liposomal).
Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take daunorubicin and cytarabine (liposomal) with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.
What are some things I need to know or do while I take Daunorubicin and Cytarabine?
- Tell all of your health care providers that you take daunorubicin and cytarabine (liposomal). This includes your doctors, nurses, pharmacists, and dentists.
- Allergic reactions have happened with daunorubicin and cytarabine (liposomal). Rarely, some reactions can be very bad or life-threatening. Talk with the doctor.
- Have blood work checked as you have been told by the doctor. Talk with the doctor.
- You will need to have your heart checked before starting daunorubicin and cytarabine (liposomal) and while taking it. This includes an ECG. Talk with your doctor.
- Heart failure has happened with daunorubicin and cytarabine (liposomal), as well as heart failure that has gotten worse in people who already have it. Tell your doctor if you have heart disease. Call your doctor right away if you have shortness of breath, a big weight gain, a heartbeat that is not normal, or swelling in the arms or legs that is new or worse.
- You may bleed more easily. Be careful and avoid injury. Use a soft toothbrush and an electric razor. Rarely, some bleeding problems have been deadly.
- You may have more chance of getting an infection. Wash hands often. Stay away from people with infections, colds, or flu.
- Talk with your doctor before getting any vaccines. Use of some vaccines with daunorubicin and cytarabine (liposomal) may either raise the chance of an infection or make the vaccine not work as well.
- This medicine may cause tissue damage if the drug leaks from the vein. Tell your nurse if you have any redness, burning, pain, swelling, blisters, skin sores, or leaking of fluid where the drug is going into your body.
- If you are 65 or older, use daunorubicin and cytarabine (liposomal) with care. You could have more side effects.
- This medicine may affect being able to father a child. Talk with the doctor.
- This medicine may cause harm to an unborn baby. A pregnancy test will be done before you start daunorubicin and cytarabine (liposomal) to show that you are NOT pregnant.
- Women must use birth control while taking daunorubicin and cytarabine (liposomal) and for some time after the last dose. Ask your doctor how long to use birth control. If you get pregnant, call your doctor right away.
- Men with a partner who may get pregnant must use birth control while taking daunorubicin and cytarabine (liposomal) and for some time after the last dose. Ask your doctor how long to use birth control. If your partner gets pregnant, call the doctor right away.
How is this medicine (Daunorubicin and Cytarabine) best taken?
Use daunorubicin and cytarabine (liposomal) as ordered by your doctor. Read all information given to you. Follow all instructions closely.
- It is given as an infusion into a vein over a period of time.
- Other drugs may be given before daunorubicin and cytarabine (liposomal) to help avoid side effects.
What do I do if I miss a dose?
- Call your doctor to find out what to do.
What are some side effects that I need to call my doctor about right away?
WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:
- Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
- Signs of bleeding like throwing up or coughing up blood; vomit that looks like coffee grounds; blood in the urine; black, red, or tarry stools; bleeding from the gums; abnormal vaginal bleeding; bruises without a cause or that get bigger; or bleeding you cannot stop.
- Signs of electrolyte problems like mood changes, confusion, muscle pain or weakness, a heartbeat that does not feel normal, seizures, not hungry, or very bad upset stomach or throwing up.
- Signs of infection like fever, chills, very bad sore throat, ear or sinus pain, cough, more sputum or change in color of sputum, pain with passing urine, mouth sores, or wound that will not heal.
- Signs of high or low blood pressure like very bad headache or dizziness, passing out, or change in eyesight.
- Signs of kidney problems like unable to pass urine, change in how much urine is passed, blood in the urine, or a big weight gain.
- Weakness on 1 side of the body, trouble speaking or thinking, change in balance, drooping on one side of the face, or blurred eyesight.
- Chest pain.
- Change in eyesight, eye pain, or very bad eye irritation.
- Hearing loss.
- Feeling very tired or weak.
What are some other side effects of Daunorubicin and Cytarabine?
All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:
- Mouth irritation or mouth sores.
- Muscle pain.
- Feeling dizzy, sleepy, tired, or weak.
- Stomach pain.
- Not hungry.
- Trouble sleeping.
- Signs of a common cold.
- Constipation, diarrhea, throwing up, and upset stomach are common with daunorubicin and cytarabine (liposomal). If these happen, talk with your doctor about ways to lower these side effects. Call your doctor right away if any of these effects bother you, do not go away, or get very bad.
These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.
You may report side effects to the FDA at 1-800-332-1088. You may also report side effects at https://www.fda.gov/medwatch.
If OVERDOSE is suspected:
If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
How do I store and/or throw out Daunorubicin and Cytarabine?
- If you need to store daunorubicin and cytarabine (liposomal) at home, talk with your doctor, nurse, or pharmacist about how to store it.
Consumer information use
- If your symptoms or health problems do not get better or if they become worse, call your doctor.
- Do not share your drugs with others and do not take anyone else's drugs.
- Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
- Throw away unused or expired drugs. Do not flush down a toilet or pour down a drain unless you are told to do so. Check with your pharmacist if you have questions about the best way to throw out drugs. There may be drug take-back programs in your area.
- Some drugs may have another patient information leaflet. Check with your pharmacist. If you have any questions about daunorubicin and cytarabine (liposomal), please talk with your doctor, nurse, pharmacist, or other health care provider.
- If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
Frequently asked questions
More about cytarabine liposomal / daunorubicin liposomal
- Side effects
- Drug interactions
- Dosage information
- During pregnancy
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- Drug class: antineoplastic combinations
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