Cytomegalovirus immune globulin
Generic Name: cytomegalovirus immune globulin (sye-toe-MEG-a-loe-vye-rus)
Brand Name: CytoGam
Cytomegalovirus immune globulin may increase the risk of blood clots. The risk may be increased in older patients, if you will be confined to a bed or chair for a period of time, if you take estrogen products, or if you have certain catheters. The risk may also be increased if you have a condition that may increase your risk of blood clots, thick blood, heart problems, or a history of blood clots. Blood clots can occur if you do not have any of these conditions. Tell your doctor right away if you develop one-sided numbness or weakness; pain, redness, tenderness, warmth or swelling in the arms or legs; change in color of an arm or leg; chest pain or discomfort; shortness of breath; fast heartbeat; or coughing up blood. Discuss any questions or concerns with your doctor.
Cytomegalovirus immune globulin is used for:
Reducing the risk of cytomegalovirus (CMV) disease associated with kidney, lung, liver, pancreas, and heart transplants. It may also be used for other conditions as determined by your doctor.
Cytomegalovirus immune globulin is an intravenous immune globulin (IGIV) enriched in antibodies against CMV. It works by temporarily increasing the antibody concentration in the body.
Do NOT use cytomegalovirus immune globulin if:
- you are allergic to any ingredient in cytomegalovirus immune globulin
- you have selective immunoglobulin A (IgA) deficiency
Contact your doctor or health care provider right away if any of these apply to you.
Before using cytomegalovirus immune globulin:
Some medical conditions may interact with cytomegalovirus immune globulin. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
- if you are pregnant, planning to become pregnant, or are breast-feeding
- if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
- if you have allergies to medicines, foods, or other substances
- if you have kidney problems, diabetes, a blood infection, or low blood volume
Some MEDICINES MAY INTERACT with cytomegalovirus immune globulin. Tell your health care provider if you are taking any other medicines, especially any of the following:
- Live vaccines (eg, measles, mumps, rubella) because the effectiveness of the vaccine may be decreased
This may not be a complete list of all interactions that may occur. Ask your health care provider if cytomegalovirus immune globulin may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.
How to use cytomegalovirus immune globulin:
Use cytomegalovirus immune globulin as directed by your doctor. Check the label on the medicine for exact dosing instructions.
- Cytomegalovirus immune globulin is usually administered as an injection at your doctor's office, hospital, or clinic. If you are using cytomegalovirus immune globulin at home, carefully follow the injection procedures taught to you by your health care provider.
- If cytomegalovirus immune globulin contains particles or is discolored, or if the vial is cracked or damaged in any way, do not use it. Ask your health care provider any questions you may have about the proper use of cytomegalovirus immune globulin.
- The infusion should begin within 6 hours after entering the vial and should be complete within 12 hours of entering the vial. This product does not contain a preservative.
- Keep this product, as well as syringes and needles, out of the reach of children. Do not reuse needles, syringes, or other materials. Dispose of properly after use. Ask your doctor, nurse, or pharmacist to explain local regulations for proper disposal.
- If you miss a dose of cytomegalovirus immune globulin, contact your doctor immediately.
Ask your health care provider any questions you may have about how to use cytomegalovirus immune globulin.
Important safety information:
- Because cytomegalovirus immune globulin is obtained from human plasma, there is a risk that viruses can be passed on to patients who use cytomegalovirus immune globulin.
- Administration of live virus vaccines (eg, measles, mumps, rubella) should be delayed until approximately 3 months after receiving cytomegalovirus immune globulin.
- Contact your health care provider at once if any of the following occur: severe headache, stiff neck, drowsiness, fever, sensitivity to light, painful eye movements, nausea, vomiting.
- Local reactions to the injection site may occur (eg, tenderness, pain, hives, swelling). Apply a warm compress. If the symptoms persist, contact your health care provider.
- LAB TESTS, including liver and kidney function and immune globulin levels, may be performed to monitor your progress or to check for side effects. Be sure to keep all doctor and lab appointments.
- Use cytomegalovirus immune globulin with caution in the ELDERLY because they may be more sensitive to its effects, such as kidney problems.
- PREGNANCY and BREAST-FEEDING: If you become pregnant, discuss with your doctor the benefits and risks of using cytomegalovirus immune globulin during pregnancy. It is unknown if cytomegalovirus immune globulin is excreted in breast milk. If you are or will be breast-feeding while you are using cytomegalovirus immune globulin, check with your doctor or pharmacist to discuss the risks to your baby.
Possible side effects of cytomegalovirus immune globulin:
All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:
Seek medical attention right away if any of these SEVERE side effects occur:
Chills; fever; flushing; joint or back pain; muscle pain; nausea; pain, redness, or swelling at injection site; vomiting; wheezing.
Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); decreased urine output; drowsiness; eye pain; hoarseness; lightheadedness, especially upon standing; sensitivity to light; severe headache; shortness of breath; stiff neck; sudden weight gain.
This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.
If OVERDOSE is suspected:
Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately.Proper storage of cytomegalovirus immune globulin:
Store cytomegalovirus immune globulin in the refrigerator between 36 and 46 degrees F (2 and 8 degrees C). Do not freeze. The product does not contain a preservative. The infusion should begin within 6 hours after entering the vial. Keep cytomegalovirus immune globulin out of the reach of children and away from pets.
- If you have any questions about cytomegalovirus immune globulin, please talk with your doctor, pharmacist, or other health care provider.
- Cytomegalovirus immune globulin is to be used only by the patient for whom it is prescribed. Do not share it with other people.
- If your symptoms do not improve or if they become worse, check with your doctor.
- Check with your pharmacist about how to dispose of unused medicine.
This information should not be used to decide whether or not to take cytomegalovirus immune globulin or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about cytomegalovirus immune globulin. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to cytomegalovirus immune globulin. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using cytomegalovirus immune globulin.
Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.
More about cytomegalovirus immune globulin
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- Drug class: immune globulins
Other brands: CytoGam