Generic Name: isavuconazonium sulfate (eye-sa-vue-na-ZOE-nee-um sul-FATE)
Brand Name: Cresemba
Cresemba is used for:
Treating certain fungal infections.
Cresemba is an azole antifungal. It works by blocking fungal cell wall growth, which results in the death of the fungus.
Do NOT use Cresemba if:
- you are allergic to any ingredient in Cresemba
- you have a certain type of irregular heartbeat (familial short QT syndrome)
- you are taking a barbiturate (eg, phenobarbital), carbamazepine, ketoconazole, rifampin, or St. John's wort
Contact your doctor or health care provider right away if any of these apply to you.
Before using Cresemba:
Some medical conditions may interact with Cresemba. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
- if you are pregnant, planning to become pregnant, or are breast-feeding
- if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
- if you have allergies to medicines, foods, or other substances
- if you are allergic to other azole antifungals (eg, fluconazole, itraconazole)
- if you have a history of irregular heartbeat
- if you have liver problems (eg, cirrhosis)
- if you are taking ritonavir. Cresemba should not be taken with certain doses of ritonavir
Some MEDICINES MAY INTERACT with Cresemba. Tell your health care provider if you are taking any other medicines, especially any of the following:
- Many other prescription and nonprescription medicines (eg, used for aches and pains, anxiety, birth control, blood flow problems, blood thinning, cancer, diabetes, drug dependence, heartburn or reflux, high blood pressure, high cholesterol, HIV, immune system suppression, infections, irregular heartbeat or other heart problems, mental or mood problems, pain, seizures, stomach or bowel problems), multivitamin products, or herbal or dietary supplements (eg, St. John's wort) because they may interact with Cresemba. Ask your doctor or pharmacist if you are unsure if any of your medicines might interact with Cresemba
This may not be a complete list of all interactions that may occur. Ask your health care provider if Cresemba may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.
How to use Cresemba:
Use Cresemba as directed by your doctor. Check the label on the medicine for exact dosing instructions.
- An extra patient leaflet is available with Cresemba. Talk to your pharmacist if you have questions about this information.
- Cresemba is given as an injection at your doctor's office, hospital, or clinic. Contact your health care provider if you have any questions.
- If you miss a dose of Cresemba, call your doctor to find out what to do.
Ask your health care provider any questions you may have about how to use Cresemba.
Important safety information:
- Tell your doctor or dentist that you take Cresemba before you receive any medical or dental care, emergency care, or surgery.
- To clear up your infection completely, use Cresemba for the full course of treatment. Keep using it even if you feel better in a few days.
- Some patients have experienced a reaction while receiving Cresemba. Tell your doctor right away if you develop burning, numbness, or tingling; chills; dizziness; fainting; or shortness of breath while you are receiving Cresemba.
- Serious and sometimes fatal liver problems have happened with Cresemba. Call your doctor right away if you have symptoms of liver problems (eg, yellowing of the skin or eyes; dark urine; pale stools; severe or persistent nausea, vomiting, or stomach pain; loss of appetite; itching).
- A severe skin reaction (Stevens-Johnson syndrome/toxic epidermal necrolysis) may happen. It can cause serious health problems that may not go away, and sometimes death. Get medical help right away if you have signs like red, swollen, blistered, or peeling skin (with or without fever); red or irritated eyes; or sores in your mouth, throat, nose, or eyes.
- Lab tests may be performed while you use Cresemba. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
- PREGNANCY and BREAST-FEEDING: Cresemba may cause harm to the fetus. If you think you may be pregnant, contact your doctor right away. Cresemba is found in breast milk. Do not breast-feed while taking Cresemba.
Possible side effects of Cresemba:
All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:
Seek medical attention right away if any of these SEVERE side effects occur:
Back pain; constipation; cough; diarrhea; headache; nausea; stomach pain; tiredness; trouble sleeping; vomiting.
Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); shortness of breath; swelling of the arms or legs; symptoms of kidney problems (eg, unable to pass urine, change in the amount of urine passed, blood in the urine, big weight gain); symptoms of low potassium levels (eg, irregular heartbeat; muscle pain, cramps, or weakness).
This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.
If OVERDOSE is suspected:
Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately.Proper storage of Cresemba:
Cresemba is handled and stored by a health care provider. You will not store it at home. Keep all medicines out of the reach of children and away from pets.
- If you have any questions about Cresemba, please talk with your doctor, pharmacist, or other health care provider.
- Cresemba is to be used only by the patient for whom it is prescribed. Do not share it with other people.
- If your symptoms do not improve or if they become worse, check with your doctor.
- Check with your pharmacist about how to dispose of unused medicine.
This information should not be used to decide whether or not to take Cresemba or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about Cresemba. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to Cresemba. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your health care provider for complete information about the risks and benefits of using Cresemba.
Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.
More about Cresemba (isavuconazonium)
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- During Pregnancy
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