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Coagulation factor IX injection (recombinant) (rfixfc)

Generic Name: coagulation factor ix injection (recombinant) (rfixfc) (ko-ag-yoo-LAY-shun)
Brand Name: Alprolix

Coagulation factor IX injection (recombinant) (rfixfc) is used for:

Preventing and controlling bleeding in patients with factor IX deficiency (hemophilia B or Christmas disease), including control and prevention of bleeding in surgical settings.

Coagulation factor IX injection (recombinant) (rfixfc) is a synthetic protein, clotting factor IX. It works by increasing the amount of clotting factor IX in the blood, helping the blood form clots and stop bleeding.

Do NOT use coagulation factor IX injection (recombinant) (rfixfc) if:

  • you are allergic to any ingredient in coagulation factor IX injection (recombinant) (rfixfc)

Contact your doctor or health care provider right away if any of these apply to you.

Before using coagulation factor IX injection (recombinant) (rfixfc):

Some medical conditions may interact with coagulation factor IX injection (recombinant) (rfixfc). Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have ever had a blood clot
  • if you have recently had surgery

Some MEDICINES MAY INTERACT with coagulation factor IX injection (recombinant) (rfixfc). However, no specific interactions with coagulation factor IX injection (recombinant) (rfixfc) are known at this time.

Ask your health care provider if coagulation factor IX injection (recombinant) (rfixfc) may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use coagulation factor IX injection (recombinant) (rfixfc):

Use coagulation factor IX injection (recombinant) (rfixfc) as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • An extra patient leaflet is available with coagulation factor IX injection (recombinant) (rfixfc). Talk to your pharmacist if you have questions about this information.
  • Coagulation factor IX injection (recombinant) (rfixfc) may be given as an injection at your doctor's office, hospital, or clinic. If you will be using coagulation factor IX injection (recombinant) (rfixfc) at home, a health care provider will teach you how to use it. Be sure you understand how to use coagulation factor IX injection (recombinant) (rfixfc). Follow the procedures you are taught when you use a dose. Contact your health care provider if you have any questions.
  • Do not use coagulation factor IX injection (recombinant) (rfixfc) if it contains particles, is cloudy or discolored, or if the vial is cracked or damaged.
  • Keep this product, as well as syringes and needles, out of the reach of children and away from pets. Do not reuse needles, syringes, or other materials. Ask your health care provider how to dispose of these materials after use. Follow all local rules for disposal.
  • If you miss a dose of coagulation factor IX injection (recombinant) (rfixfc), contact your doctor right away.

Ask your health care provider any questions you may have about how to use coagulation factor IX injection (recombinant) (rfixfc).

Important safety information:

  • Patients receiving clotting factors sometimes develop antibodies or inhibitors to the medicine. This makes coagulation factor IX injection (recombinant) (rfixfc) less effective. If coagulation factor IX injection (recombinant) (rfixfc) stops working or does not work as well as it has before, contact your doctor immediately for instructions.
  • Tell your doctor or dentist that you take coagulation factor IX injection (recombinant) (rfixfc) before you receive any medical or dental care, emergency care, or surgery.
  • Blood clots have happened in certain people using products that contain factor IX. Discuss any questions or concerns with your doctor.
  • LAB TESTS, including factor IX levels, may be performed while you use coagulation factor IX injection (recombinant) (rfixfc). These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
  • PREGNANCY and BREAST-FEEDING: It is not known if coagulation factor IX injection (recombinant) (rfixfc) can cause harm to the fetus. If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using coagulation factor IX injection (recombinant) (rfixfc) while you are pregnant. It is not known if this medicine is found in breast milk. If you are or will be breast-feeding while you use coagulation factor IX injection (recombinant) (rfixfc), check with your doctor. Discuss any possible risks to your baby.

Possible side effects of coagulation factor IX injection (recombinant) (rfixfc):

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Headache; burning, numbness, or tingling in the mouth.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest or throat; swelling of the mouth, face, lips, throat, or tongue; unusual hoarseness; wheezing); burning, numbness, or tingling that is not normal; calf or leg pain, swelling, or tenderness; chest pain or pressure; confusion; coughing up blood; fainting; one-sided weakness; restlessness; severe nausea or vomiting; shortness of breath; sudden, severe headache or dizziness; vision or speech changes.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately.

Proper storage of coagulation factor IX injection (recombinant) (rfixfc):

Store coagulation factor IX injection (recombinant) (rfixfc) in the refrigerator between 36 and 46 degrees F (2 and 8 degrees C). Be sure you know how long you can store coagulation factor IX injection (recombinant) (rfixfc). Do not freeze. Coagulation factor IX injection (recombinant) (rfixfc) may be stored at room temperature up to 86 degrees F (30 degrees C) for up to 6 months. You should make note of the date the product was placed at room temperature in the space provided on the outer carton. Do not use past the expiration date. Do not place back in the refrigerator after storage at room temperature. After mixing, coagulation factor IX injection (recombinant) (rfixfc) must be used within 3 hours. Throw away any unused portion. Store away from heat, moisture, and light. Do not store in the bathroom. Keep coagulation factor IX injection (recombinant) (rfixfc) out of the reach of children and away from pets.

General information:

  • If you have any questions about coagulation factor IX injection (recombinant) (rfixfc), please talk with your doctor, pharmacist, or other health care provider.
  • Coagulation factor IX injection (recombinant) (rfixfc) is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.
  • Check with your pharmacist about how to dispose of unused medicine.

This information should not be used to decide whether or not to take coagulation factor IX injection (recombinant) (rfixfc) or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about coagulation factor IX injection (recombinant) (rfixfc). It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to coagulation factor IX injection (recombinant) (rfixfc). This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using coagulation factor IX injection (recombinant) (rfixfc).

Review Date: November 3, 2016

Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.

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