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Chlorpheniramine/ methscopolamine chewable tablet

Generic Name: chlorpheniramine/methscopolamine (KLOR-fen-IR-a-meen/METH-skoe-POL-a-meen)
Brand Name: Dexodryl

Chlorpheniramine/ methscopolamine chewable tablet is used for:

Relieving sneezing, runny nose, and watery eyes due to colds, flu, or hay fever. It may also be used for other conditions as determined by your doctor.

Chlorpheniramine/methscopolamine chewable tablet is an antihistamine and anticholinergic combination. It works by blocking a substance in the body that causes sneezing, runny nose, and watery eyes. It also dries the nose and chest.

Do NOT use chlorpheniramine/ methscopolamine chewable tablet if:

  • you are allergic to any ingredient in chlorpheniramine/methscopolamine chewable tablet
  • you are taking sodium oxybate (GHB) or a monamine oxidase inhibitor (MAOI) (eg, phenelzine)
  • you have severe heart blood vessel disease, severe high blood pressure, narrow-angle glaucoma, severe bleeding, severe irritation or other serious problems with the esophagus (eg, esophageal achalasia), peptic ulcer, a blockage of the stomach or bowel, bowel motility problems, severe bowel inflammation (eg, ulcerative colitis), or muscle problems (eg, myasthenia gravis)
  • you have a blockage of the bladder, are unable to urinate, or are having an asthma attack

Contact your doctor or health care provider right away if any of these apply to you.

Before using chlorpheniramine/ methscopolamine chewable tablet:

Some medical conditions may interact with chlorpheniramine/methscopolamine chewable tablet. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have a hernia or a history of high blood pressure, diabetes, blood vessel problems, stroke, seizures, overactive thyroid, nerve problems, prostate gland problems, heart problems (eg, irregular heartbeat, congestive heart failure), sleep apnea, asthma, lung problems (eg, emphysema, chronic obstructive pulmonary disease [COPD]), or glaucoma, or you are at risk of developing glaucoma
  • if you have trouble urinating or severe constipation

Some MEDICINES MAY INTERACT with chlorpheniramine/methscopolamine chewable tablet. Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Potassium products because they do not move properly through the intestines while you are taking chlorpheniramine/methscopolamine chewable tablet
  • Anticholinergic medicines (eg, benztropine), barbiturates (eg, phenobarbital), phenothiazines (eg, thioridazine), or tricyclic antidepressants (eg, amitriptyline) because they may increase the risk of chlorpheniramine/methscopolamine chewable tablet's side effects
  • MAOIs (eg, phenelzine) or sodium oxybate (GHB) because the risk of serious side effects, such as high blood pressure or severe drowsiness, may be increased
  • Beta-blockers (eg, propranolol), digoxin, or hydantoins because the risk of their side effects may be increased by chlorpheniramine/methscopolamine chewable tablet

This may not be a complete list of all interactions that may occur. Ask your health care provider if chlorpheniramine/methscopolamine chewable tablet may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use chlorpheniramine/ methscopolamine chewable tablet:

Use chlorpheniramine/methscopolamine chewable tablet as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Take chlorpheniramine/methscopolamine chewable tablet by mouth with or without food.
  • Chew well before swallowing.
  • Do not take an antacid or medicine for diarrhea within 1 hour before or 2 hours after you take chlorpheniramine/methscopolamine chewable tablet.
  • If you miss a dose of chlorpheniramine/methscopolamine chewable tablet and you are using it regularly, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use chlorpheniramine/methscopolamine chewable tablet.

Important safety information:

  • Chlorpheniramine/methscopolamine chewable tablet may cause drowsiness, dizziness, or blurred vision. These effects may be worse if you take it with alcohol or certain medicines. Use chlorpheniramine/methscopolamine chewable tablet with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
  • Check with your doctor before you drink alcohol or use medicines that may cause drowsiness (eg, sleep aids, muscle relaxers) while you are using chlorpheniramine/methscopolamine chewable tablet; it may add to their effects. Ask your pharmacist if you have questions about which medicines may cause drowsiness.
  • Do not take more than the recommended dose or use for longer than prescribed without checking with your doctor.
  • If your symptoms do not get better within 7 days, if they get worse, or if they occur with a fever, check with your doctor.
  • Chlorpheniramine/methscopolamine chewable tablet may cause dry mouth. To relieve dry mouth, suck on sugarless hard candy or ice chips, chew sugarless gum, drink water, or use a saliva substitute.
  • Chlorpheniramine/methscopolamine chewable tablet may reduce sweating. Do not become overheated in hot weather or during exercise or during other activities; heatstroke may occur.
  • Chlorpheniramine/methscopolamine chewable tablet may cause you to become sunburned more easily. Avoid the sun, sunlamps, or tanning booths until you know how you react to chlorpheniramine/methscopolamine chewable tablet. Use a sunscreen or wear protective clothing if you must be outside for more than a short time.
  • Chlorpheniramine/methscopolamine chewable tablet may interfere with certain lab tests. Be sure your doctor and lab personnel know you are taking chlorpheniramine/methscopolamine chewable tablet.
  • Use chlorpheniramine/methscopolamine chewable tablet with caution in the ELDERLY; they may be more sensitive to its effects.
  • Caution is advised with using chlorpheniramine/methscopolamine chewable tablet in CHILDREN; they may be more sensitive to its effects, especially excitability.
  • Chlorpheniramine/methscopolamine chewable tablet should be used with extreme caution in CHILDREN younger than 6 years old; safety and effectiveness in these children have not been confirmed.
  • PREGNANCY and BREAST-FEEDING: It is not known if chlorpheniramine/methscopolamine chewable tablet can cause harm to the fetus. If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using chlorpheniramine/methscopolamine chewable tablet while you are pregnant. It is not known if this medicine is found in breast milk. Do not breast-feed while taking chlorpheniramine/methscopolamine chewable tablet.

Possible side effects of chlorpheniramine/ methscopolamine chewable tablet:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Blurred vision; change in appetite; constipation; dizziness; drowsiness; dry mouth; nausea; nervousness; stomach upset or pain; trouble sleeping.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); confusion; difficulty urinating; fainting or feeling faint; fast heartbeat; fever, chills, or persistent sore throat; flushing; hallucinations; seizures; severe clumsiness; severe or persistent nervousness, dizziness, or trouble sleeping; severe drowsiness; shortness of breath; unusual bruising or bleeding; unusual tiredness or weakness.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include difficulty breathing; fixed/large pupils; flushing; hot, dry skin; irregular heartbeat; loss of consciousness; mental or mood changes; ringing in the ears; seizures; severe drowsiness, dizziness, or headache; severe or persistent nausea or vomiting.

Proper storage of chlorpheniramine/methscopolamine chewable tablet:

Store at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep chlorpheniramine/methscopolamine chewable tablet out of the reach of children and away from pets.

General information:

  • If you have any questions about chlorpheniramine/methscopolamine chewable tablet, please talk with your doctor, pharmacist, or other health care provider.
  • Chlorpheniramine/methscopolamine chewable tablet is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.
  • Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about chlorpheniramine/methscopolamine chewable tablet. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: June 3, 2015