Generic Name: chlordiazepoxide/clidinium (KLOR-dye-az-e-POX-ide/kli-DIN-ee-um)
Brand Name: Librax
Chlordiazepoxide/ clidinium is used for:
Treating stomach or bowel problems such as ulcers, irritability, or inflammation.
Chlordiazepoxide/clidinium is a benzodiazepine and anticholinergic combination. It works by relieving anxiety and reducing digestive secretions. This helps to improve certain stomach or bowel conditions.
Do NOT use chlordiazepoxide/ clidinium if:
- you are allergic to any ingredient in chlordiazepoxide/clidinium
- you have problems swallowing, or other severe esophagus problems (eg, inflammation, reflux)
- you have severe stomach or bowel problems (eg, blockage, inflammation, loss of muscle tone)
- you have a blockage of your bladder, an enlarged prostate, glaucoma, myasthenia gravis, or severe liver problems
- you have severe mental problems (eg, psychosis)
- you are taking sodium oxybate (GHB)
Contact your doctor or health care provider right away if any of these apply to you.
Before using chlordiazepoxide/ clidinium:
Some medical conditions may interact with chlordiazepoxide/clidinium. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
- if you are pregnant, planning to become pregnant, or are breast-feeding
- if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
- if you have allergies to medicines, foods, or other substances
- if you have kidney or liver problems
- if you have problems urinating
- if you have a history of blood problems (eg, porphyria), glaucoma, increased pressure in the eye, or abnormal electroencephalograms (EEGs)
- if you have a history of heart problems (eg, irregular heartbeat, congestive heart failure), hernia, lung or breathing problems (eg, chronic obstructive pulmonary disease [COPD]), or nerve and muscle problems
- if you have a history of mood or mental problems (eg, anxiety, depression), suicidal thoughts or actions, or a history of alcohol or other substance dependence or abuse
- if you have been very ill
Some MEDICINES MAY INTERACT with chlordiazepoxide/clidinium. Tell your health care provider if you are taking any other medicines, especially any of the following:
- Clozapine, methadone, or sodium oxybate (GHB) because delirium, severe drowsiness, severe breathing problems, or serious low blood pressure may occur
- Anticoagulants (eg, warfarin) because changes in blood clotting may occur
- Azole antifungals (eg, ketoconazole), disulfiram, monoamine oxidase inhibitors (MAOIs) (eg, phenelzine), nefazodone, omeprazole, or phenothiazines (eg, thioridazine) because they may increase the risk of chlordiazepoxide/clidinium's side effects
- Rifampin because it may decrease chlordiazepoxide/clidinium's effectiveness
- Hydantoins (eg, phenytoin) because the risk of their side effects may be increased by chlordiazepoxide/clidinium
This may not be a complete list of all interactions that may occur. Ask your health care provider if chlordiazepoxide/clidinium may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.
How to use chlordiazepoxide/ clidinium:
Use chlordiazepoxide/clidinium as directed by your doctor. Check the label on the medicine for exact dosing instructions.
- Take chlordiazepoxide/clidinium by mouth before meals and at bedtime, unless otherwise directed by your doctor.
- If you miss a dose of chlordiazepoxide/clidinium, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.
Ask your health care provider any questions you may have about how to use chlordiazepoxide/clidinium.
Important safety information:
- Chlordiazepoxide/clidinium may cause drowsiness. This effect may be worse if you take it with alcohol or certain medicines. Use chlordiazepoxide/clidinium with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
- Do not drink alcohol or use medicines that may cause drowsiness (eg, sleep aids, muscle relaxers) while you are using chlordiazepoxide/clidinium; it may add to their effects. Ask your pharmacist if you have questions about which medicines may cause drowsiness.
- Do NOT take more than the recommended dose or use for longer than prescribed without checking with your doctor.
- Lab tests, including liver function and complete blood cell counts, may be performed while you use chlordiazepoxide/clidinium. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
- Use chlordiazepoxide/clidinium with caution in the ELDERLY; they may be more sensitive to its effects, especially confusion, drowsiness, and loss of coordination.
- Chlordiazepoxide/clidinium should be used with extreme caution in CHILDREN; safety and effectiveness in children have not been confirmed.
- PREGNANCY and BREAST-FEEDING: Chlordiazepoxide/clidinium may cause harm to the fetus. If you think you may be pregnant, contact your doctor. You will need to discuss the benefits and risks of using chlordiazepoxide/clidinium while you are pregnant. Chlordiazepoxide/clidinium is found in breast milk. Do not breast-feed while taking chlordiazepoxide/clidinium.
Some people who use chlordiazepoxide/clidinium for a long time may develop a need to continue taking it. People who take high doses are also at risk. This is known as DEPENDENCE or addiction.
If you stop taking chlordiazepoxide/clidinium suddenly, you may have WITHDRAWAL symptoms. These may include unpleasant feelings. In more severe cases, you may have stomach and muscle cramps, vomiting, sweating, and shakiness. Seizures may rarely occur. If you take chlordiazepoxide/clidinium for more than 1 to 2 weeks, do not stop taking it without talking to your doctor.
Possible side effects of chlordiazepoxide/ clidinium:
All medicines may cause side effects, but many people have no, or minor side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:
Seek medical attention right away if any of these SEVERE side effects occur:
Blurred vision; constipation; drowsiness; dry mouth.
Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); behavior changes (eg, excessive anger or rage); changes in sexual desire; changes in the menstrual period; confusion; difficulty urinating; excitability; fainting; loss of coordination; sore throat or fever; swelling; yellowing of the skin or eyes.
This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.
If OVERDOSE is suspected:
Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include confusion; extreme drowsiness; loss of consciousness; slowed reflexes.Proper storage of chlordiazepoxide/clidinium:
Store chlordiazepoxide/clidinium at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Keep chlordiazepoxide/clidinium out of the reach of children and away from pets.
- If you have any questions about chlordiazepoxide/clidinium, please talk with your doctor, pharmacist, or other health care provider.
- Chlordiazepoxide/clidinium is to be used only by the patient for whom it is prescribed. Do not share it with other people.
- If your symptoms do not improve or if they become worse, check with your doctor.
- Check with your pharmacist about how to dispose of unused medicine.
This information should not be used to decide whether or not to take chlordiazepoxide/clidinium or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about chlordiazepoxide/clidinium. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to chlordiazepoxide/clidinium. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using chlordiazepoxide/clidinium.
Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.
More about chlordiazepoxide/clidinium
- Side Effects
- During Pregnancy
- Dosage Information
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- Drug Interactions
- Support Group
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- Drug class: anticholinergics/antispasmodics
Other brands: Librax