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Carbinoxamine/ dextromethorphan/ phenylephrine drops
Generic Name: carbinoxamine/dextromethorphan/phenylephrine (kar-bi-NOX-a-meen/dex-troe-meth-OR-fan/fen-i-LEF-rin)
Brand Name: Examples include DMax Pediatric and Trituss-A
Carbinoxamine/ dextromethorphan/ phenylephrine drops are used for:
Relieving sinus congestion, runny nose, sneezing, and cough due to colds, upper respiratory infections, and allergies. It may also be used for other conditions as determined by your doctor.
Carbinoxamine/dextromethorphan/phenylephrine drops are a decongestant, antihistamine, and cough suppressant combination. It works by constricting blood vessels and reducing swelling in the nasal passages, which helps you breathe more easily. The antihistamine works by blocking the action of histamine, which helps reduce symptoms such as watery eyes and sneezing, while the cough suppressant works in the brain to reduce the cough reflex.
Do NOT use carbinoxamine/ dextromethorphan/ phenylephrine drops if:
- you are allergic to any ingredient in carbinoxamine/dextromethorphan/phenylephrine drops
- you have severe high blood pressure, severe heart blood vessel disease, rapid heartbeat, or severe heart problems
- you are unable to urinate or are having an asthma attack
- you are taking sodium oxybate (GHB) or you have taken furazolidone or a monoamine oxidase (MAO) inhibitor (eg, phenelzine) within the last 14 days
Contact your doctor or health care provider right away if any of these apply to you.
Before using carbinoxamine/ dextromethorphan/ phenylephrine drops:
Some medical conditions may interact with carbinoxamine/dextromethorphan/phenylephrine drops. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
- if you are pregnant, plan to become pregnant, or are breast-feeding
- if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
- if you have allergies to medicines, foods, or other substances
- if you have a fast, slow, or irregular heartbeat
- if you have a history of adrenal gland problems (eg, tumor); heart problems; high blood pressure; diabetes; heart blood vessel problems; stroke; glaucoma; a blockage of your stomach, intestines, or bladder; ulcers; trouble urinating; an enlarged prostate or other prostate problems; seizures; or an overactive thyroid
- if you have a history of asthma, chronic cough, chronic obstructive pulmonary disease (COPD), or other lung problems (eg, chronic bronchitis, emphysema), or if your cough produces large amounts of mucus
Some MEDICINES MAY INTERACT with carbinoxamine/dextromethorphan/phenylephrine drops. Tell your health care provider if you are taking any other medicines, especially any of the following:
- Beta-blockers (eg, propranolol), COMT inhibitors (eg, tolcapone), furazolidone, indomethacin, MAO inhibitors (eg, phenelzine), sodium oxybate (GHB), or tricyclic antidepressants (eg, amitriptyline) because side effects of carbinoxamine/dextromethorphan/phenylephrine drops may be increased
- Digoxin or droxidopa because the risk of irregular heartbeat or heart attack may be increased
- Bromocriptine or hydantoins (eg, phenytoin) because the risk of side effects may be increased by carbinoxamine/dextromethorphan/phenylephrine drops
- Guanadrel, guanethidine, mecamylamine, methyldopa, or reserpine because their effectiveness may be decreased by carbinoxamine/dextromethorphan/phenylephrine drops
This may not be a complete list of all interactions that may occur. Ask your health care provider if carbinoxamine/dextromethorphan/phenylephrine drops may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.
How to use carbinoxamine/ dextromethorphan/ phenylephrine drops:
Use carbinoxamine/dextromethorphan/phenylephrine drops as directed by your doctor. Check the label on the medicine for exact dosing instructions.
- Carbinoxamine/dextromethorphan/phenylephrine drops may be taken with or without food.
- Use the dropper that comes with carbinoxamine/dextromethorphan/phenylephrine drops to measure your dose. Ask your pharmacist for help if you are unsure of how to measure your dose.
- If you miss a dose of carbinoxamine/dextromethorphan/phenylephrine drops, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.
Ask your health care provider any questions you may have about how to use carbinoxamine/dextromethorphan/phenylephrine drops.
Important safety information:
- Carbinoxamine/dextromethorphan/phenylephrine drops may cause dizziness, drowsiness, or blurred vision. Do not drive, operate machinery, or do anything else that could be dangerous until you know how you react to carbinoxamine/dextromethorphan/phenylephrine drops. Using carbinoxamine/dextromethorphan/phenylephrine drops alone, with certain other medicines, or with alcohol may lessen your ability to drive or perform other potentially dangerous tasks.
- Do not take appetite suppressants while you are taking carbinoxamine/dextromethorphan/phenylephrine drops without checking with your doctor.
- Carbinoxamine/dextromethorphan/phenylephrine drops contains phenylephrine. Before you begin taking any new prescription or nonprescription medicine, read the ingredients to see if it also contains phenylephrine. If it does or if you are uncertain, contact your doctor or pharmacist.
- Do NOT exceed the recommended dose or take carbinoxamine/dextromethorphan/phenylephrine drops for longer than prescribed without checking with your doctor.
- If your symptoms do not improve within 5 to 7 days or if they become worse, check with your doctor.
- Carbinoxamine/dextromethorphan/phenylephrine drops may cause increased sensitivity to the sun. Avoid exposure to the sun, sunlamps, or tanning booths until you know how you react to carbinoxamine/dextromethorphan/phenylephrine drops. Use a sunscreen or protective clothing if you must be outside for a prolonged period.
- If you are scheduled for allergy skin testing, do not take carbinoxamine/dextromethorphan/phenylephrine drops for several days before the test because it may decrease your response to the skin tests.
- Before you have any medical or dental treatments, emergency care, or surgery, tell the doctor or dentist that you are using carbinoxamine/dextromethorphan/phenylephrine drops.
- Use carbinoxamine/dextromethorphan/phenylephrine drops with caution in the ELDERLY because they may be more sensitive to its effects.
- Caution is advised when using carbinoxamine/dextromethorphan/phenylephrine drops in CHILDREN because they may be more sensitive to its effects.
- PREGNANCY and BREAST-FEEDING: If you become pregnant while taking carbinoxamine/dextromethorphan/phenylephrine drops, discuss with your doctor the benefits and risks of using carbinoxamine/dextromethorphan/phenylephrine drops during pregnancy. It is unknown if carbinoxamine/dextromethorphan/phenylephrine drops are excreted in breast milk. Do not breast-feed while taking carbinoxamine/dextromethorphan/phenylephrine drops.
Possible side effects of carbinoxamine/ dextromethorphan/ phenylephrine drops:
All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:
Seek medical attention right away if any of these SEVERE side effects occur:
Constipation; diarrhea; dizziness; drowsiness; excitability; headache; loss of appetite; nausea; nervousness or anxiety; trouble sleeping; upset stomach; vomiting; weakness.
Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); difficulty urinating or inability to urinate; fast or irregular heartbeat; hallucinations; seizures; severe dizziness, lightheadedness, or headache; tremor; trouble sleeping; vision changes.
This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.
If OVERDOSE is suspected:
Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include blurred vision; confusion; hallucinations; seizures; severe dizziness, lightheadedness, or headache; severe drowsiness; unusually fast, slow, or irregular heartbeat; vomiting.Proper storage of carbinoxamine/dextromethorphan/phenylephrine drops:
Store carbinoxamine/dextromethorphan/phenylephrine drops at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep carbinoxamine/dextromethorphan/phenylephrine drops out of the reach of children and away from pets.
- If you have any questions about carbinoxamine/dextromethorphan/phenylephrine drops, please talk with your doctor, pharmacist, or other health care provider.
- Carbinoxamine/dextromethorphan/phenylephrine drops are to be used only by the patient for whom it is prescribed. Do not share it with other people.
- If your symptoms do not improve or if they become worse, check with your doctor.
- Check with your pharmacist about how to dispose of unused medicine.
This information is a summary only. It does not contain all information about carbinoxamine/dextromethorphan/phenylephrine drops. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.