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Boceprevir

Generic Name: Boceprevir (boe SE pre vir)
Brand Name: Victrelis

Medically reviewed on May 2, 2018

Uses of Boceprevir:

What do I need to tell my doctor BEFORE I take Boceprevir?

  • If you have an allergy to boceprevir or any other part of boceprevir.
  • If you are allergic to any drugs like this one, any other drugs, foods, or other substances. Tell your doctor about the allergy and what signs you had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
  • If you have liver problems other than hepatitis C.
  • If you are not taking ribavirin or peginterferon alfa.
  • If you are of childbearing age, but are not using 2 kinds of birth control or if you are planning to get pregnant during your care or within 6 months after care has ended.
  • If you are a man with a sex partner who is pregnant or plans on getting pregnant at any time while you are being treated or within 6 months after your care has ended.
  • If you are pregnant or may be pregnant. Do not take boceprevir if you are pregnant.
  • If you are breast-feeding or plan to breast-feed.
  • If you take any drugs (prescription or OTC, natural products, vitamins) that must not be taken with boceprevir, like certain drugs that are used for high cholesterol, HIV, or seizures. There are many drugs that must not be taken with boceprevir.
  • If you are taking St. John's wort. Do not take St. John's wort with boceprevir. This medicine may not work as well.

This is not a list of all drugs or health problems that interact with boceprevir.

Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take boceprevir with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.

What are some things I need to know or do while I take Boceprevir?

  • Tell all of your health care providers that you take boceprevir. This includes your doctors, nurses, pharmacists, and dentists.
  • Avoid driving and doing other tasks or actions that call for you to be alert or have clear eyesight until you see how boceprevir affects you.
  • Do not run out of boceprevir.
  • Have blood work checked as you have been told by the doctor. Talk with the doctor.
  • You may have more chance of getting an infection. Wash hands often. Stay away from people with infections, colds, or flu.
  • You may bleed more easily. Be careful and avoid injury. Use a soft toothbrush and an electric razor.
  • This medicine does not stop the spread of diseases like HIV or hepatitis that are passed through blood or having sex. Do not have any kind of sex without using a latex or polyurethane condom. Do not share needles or other things like toothbrushes or razors. Talk with your doctor.
  • This medicine may affect how much of some other drugs are in your body. If you are taking other drugs, talk with your doctor. You may need to have your blood work checked more closely while taking boceprevir with your other drugs.
  • This medicine may be used with other drugs to treat hepatitis C. If you are also taking other drugs to treat hepatitis C, talk with the doctor about the risks and side effects that may happen.
  • If you are 65 or older, use boceprevir with care. You could have more side effects.
  • Use 2 kinds of birth control that you can trust while using boceprevir and for 6 months after stopping boceprevir.
  • If you get pregnant while taking boceprevir or within 6 months after your last dose, call your doctor right away.
  • If you are a man and have sex with a female who could get pregnant, protect her from pregnancy during care and for 6 months after care ends. Use birth control that you can trust.
  • If you are a man and your sex partner gets pregnant while you take boceprevir or within 6 months after your last dose, call your doctor right away.

How is this medicine (Boceprevir) best taken?

Use boceprevir as ordered by your doctor. Read all information given to you. Follow all instructions closely.

  • Take boceprevir with food.
  • Keep taking boceprevir as you have been told by your doctor or other health care provider, even if you feel well.
  • It is important that you do not miss or skip a dose of boceprevir during treatment.
  • If you stop taking any of your other drugs to treat hepatitis C, talk with your doctor. You may need to stop taking boceprevir also.

What do I do if I miss a dose?

  • Take a missed dose as soon as you think about it, with food.
  • If it is less than 2 hours until your next dose, skip the missed dose and go back to your normal time.
  • Do not take 2 doses at the same time or extra doses.

What are some side effects that I need to call my doctor about right away?

WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:

  • Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
  • Signs of infection like fever, chills, very bad sore throat, ear or sinus pain, cough, more sputum or change in color of sputum, pain with passing urine, mouth sores, or wound that will not heal.
  • Signs of bleeding like throwing up blood or throw up that looks like coffee grounds; coughing up blood; blood in the urine; black, red, or tarry stools; bleeding from the gums; vaginal bleeding that is not normal; bruises without a reason or that get bigger; or any bleeding that is very bad or that you cannot stop.
  • Feeling very tired or weak.
  • Pale skin.
  • Very bad dizziness or passing out.
  • Shortness of breath.

What are some other side effects of Boceprevir?

All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:

These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.

You may report side effects to the FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.

See also: Side effects (in more detail)

If OVERDOSE is suspected:

If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

How do I store and/or throw out Boceprevir?

  • Store capsules in a refrigerator.
  • You may also store boceprevir at room temperature. If stored at room temperature, throw away any part not used after 3 months.
  • Store in original container.
  • Protect from heat.
  • Store in a dry place. Do not store in a bathroom.
  • Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
  • Throw away unused or expired drugs. Do not flush down a toilet or pour down a drain unless you are told to do so. Check with your pharmacist if you have questions about the best way to throw out drugs. There may be drug take-back programs in your area.

Consumer information use

  • If your symptoms or health problems do not get better or if they become worse, call your doctor.
  • Do not share your drugs with others and do not take anyone else's drugs.
  • Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
  • Talk with the doctor before starting any new drug, including prescription or OTC, natural products, or vitamins.
  • Some drugs may have another patient information leaflet. Check with your pharmacist. If you have any questions about boceprevir, please talk with your doctor, nurse, pharmacist, or other health care provider.
  • If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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