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Atazanavir powder for oral suspension

Generic Name: atazanavir (A-ta-ZAN-a-vir)
Brand Name: Reyataz

Atazanavir powder for oral suspension is used for:

Treating HIV infection along with other medicines.

Atazanavir powder for oral suspension is an HIV protease inhibitor. It works by blocking the growth of HIV.

Do NOT use atazanavir powder for oral suspension if:

  • your child is allergic to any ingredient in atazanavir powder for oral suspension
  • your child has severe liver problems
  • your child is taking alfuzosin, cisapride, an ergot derivative (eg, ergotamine), indinavir, irinotecan, lovastatin, nevirapine, oral midazolam, pimozide, rifampin, salmeterol, simvastatin, St. John's wort, or triazolam
  • your child is taking sildenafil for pulmonary arterial hypertension (PAH)

Contact the doctor or health care provider right away if any of these apply to your child.

Before using atazanavir powder for oral suspension:

Some medical conditions may interact with atazanavir powder for oral suspension. Tell the doctor or pharmacist if your child has any medical conditions, especially if any of the following apply to your child:

  • if your child is pregnant, planning to become pregnant, or is breast-feeding
  • if your child is taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if your child has allergies to medicines, foods, or other substances
  • if your child has hemophilia, diabetes or high blood sugar, high cholesterol, an irregular heartbeat, gallbladder problems (eg, gallstones), phenylketonuria (PKU), or liver problems (eg, hepatitis B or C)
  • if your child has kidney problems or kidney stones or is on dialysis

Some MEDICINES MAY INTERACT with atazanavir powder for oral suspension. Tell the health care provider if your child is taking any other medicines, especially any of the following:

  • Many prescription and nonprescription medicines (eg, used for aches and pains, allergies, angina, asthma or other lung or breathing problems, birth control, blood thinning, blood vessel problems, cancer, Cushing syndrome, cystic fibrosis, depression or other mental or mood problems, diabetes, enlarged prostate gland, erectile dysfunction, gout, heartburn or reflux disease, hepatitis C, high blood pressure, high cholesterol, HIV, immune system suppression, infections, inflammation, irregular heartbeat or other heart problems, low blood sodium levels, migraine, nausea and vomiting, opioid addiction, overactive bladder, pulmonary hypertension, seizures, sleep aid, Tourette disorder), multivitamin products, and herbal or dietary supplements (eg, St. John's wort) because they may interact with atazanavir powder for oral suspension. Ask the doctor or pharmacist if you are unsure if any of your child's medicines might interact with atazanavir powder for oral suspension.

This may not be a complete list of all interactions that may occur. Ask the health care provider if atazanavir powder for oral suspension may interact with other medicines that your child takes. Check with the health care provider before your child starts, stops, or changes the dose of any medicine.

How to use atazanavir powder for oral suspension:

Give atazanavir powder for oral suspension as directed by the doctor. Check the label on the medicine for exact dosing instructions.

  • An extra patient leaflet is available with atazanavir powder for oral suspension. Talk to your pharmacist if you have questions about this information.
  • Give atazanavir powder for oral suspension by mouth with food.
  • Before giving, mix the powder with soft food (eg, applesauce, yogurt). If you cannot do this, mix with a drink (eg, milk, infant formula, water). Mix atazanavir powder for oral suspension as the doctor has told you or read the package insert.
  • If you use infant formula to mix the powder, give the medicine using an oral dosing syringe. Do not give using an infant bottle.
  • Give atazanavir powder for oral suspension within 1 hour of mixing.
  • If your child also takes an H2antagonist (eg, cimetidine) or a proton pump inhibitor (PPI) (eg, omeprazole), talk with the doctor about how to give it with atazanavir powder for oral suspension.
  • If your child also takes an antacid or didanosine, give atazanavir powder for oral suspension at least 2 hours before or 1 hour after the antacid or didanosine.
  • Give atazanavir powder for oral suspension on a regular schedule to be sure your child gets the most benefit from it.
  • Giving atazanavir powder for oral suspension at the same time each day will help you remember to give it.
  • Continue to give atazanavir powder for oral suspension even if your child feels well. Do not miss giving your child any doses.
  • If you miss giving your child a dose of atazanavir powder for oral suspension, give it as soon as possible. If it is almost time for your child's next dose, skip the missed dose and go back to your child's regular dosing schedule. Do not give 2 doses at once.

Ask the health care provider any questions you may have about how to give atazanavir powder for oral suspension.

Important safety information:

  • Tell the doctor or dentist that your child takes atazanavir powder for oral suspension before your child receives any medical or dental care, emergency care, or surgery.
  • Atazanavir powder for oral suspension interacts with many other medicines. The risk of atazanavir powder for oral suspension's side effects may be increased or atazanavir powder for oral suspension's effectiveness may be decreased. The risk of the other medicines' side effects may also be increased. This may include severe, life-threatening, or fatal side effects. Check with the doctor and pharmacist to make sure that it is safe for your child to take atazanavir powder for oral suspension with all of their other medicines (prescription or OTC, natural products, vitamins).
  • Atazanavir powder for oral suspension is not a cure for HIV infection. Patients may still get illnesses and infections associated with HIV. Be sure your child remains under the care of the doctor.
  • When your child's medicine supply is low, get more from the doctor or pharmacist as soon as you can. Do not stop giving atazanavir powder for oral suspension to your child, even for a short period of time. If you do, the virus may grow resistant to the medicine and become harder to treat.
  • Atazanavir powder for oral suspension does not stop the spread of HIV to others through blood. Be sure your child does not share needles, injection supplies, or items like toothbrushes or razors. Talk with the health care provider about ways to prevent the spread of HIV to others.
  • If your child is or may be sexually active, atazanavir powder for oral suspension does not stop the spread of HIV to others through sexual contact. Be sure your child does not have any kind of sex without protection (eg, latex or polyurethane condoms) if your child has HIV infection.
  • Do NOT give more than the recommended dose, change the dose, or stop giving atazanavir powder for oral suspension without checking with the doctor.
  • Changes in body fat (eg, an increased amount of fat in the upper back, neck, breast, and trunk, and loss of fat from the legs, arms, and face) may occur in some patients taking atazanavir powder for oral suspension. The cause and long-term effects of these changes are unknown. Discuss any concerns with the doctor.
  • Hormonal birth control (eg, birth control pills) may not work as well while using atazanavir powder for oral suspension. If your child is or may be sexually active, have your child use an extra form of birth control (eg, condoms) to prevent pregnancy.
  • Atazanavir powder for oral suspension may improve immune system function. This may reveal hidden infections in some patients. Tell the doctor right away if your child has symptoms of an infection (eg, fever, sore throat, weakness, cough, shortness of breath) or any other unusual symptoms after starting atazanavir powder for oral suspension.
  • Mild rashes without other symptoms have been reported in patients who take atazanavir powder for oral suspension. These rashes usually go away within 2 weeks with no change in treatment. Contact the doctor if a rash occurs. Rashes may also occur along with other serious and sometimes fatal symptoms. Contact the doctor right away if your child has a rash along with blisters, fever, general ill feeling, mouth sores, muscle or joint ache, red or swollen eyes, shortness of breath, swelling of the face, symptoms of kidney problems (eg, decreased urination), or symptoms of liver problems (eg, dark urine, loss of appetite, pale stools, yellowing of the eyes or skin).
  • This product contains phenylalanine. If your child must have a diet that is low in phenylalanine, talk with the doctor.
  • Atazanavir powder for oral suspension may raise your child's blood sugar. High blood sugar may make your child feel confused, drowsy, or thirsty. It can also make your child flush, breathe faster, or have a fruit-like breath odor. If these symptoms occur, tell the doctor right away.
  • Diabetes patients - Check blood sugar levels closely. Ask the doctor before you change the dose of your child's diabetes medicine.
  • Hemophilia patients - Some people with hemophilia have developed increased bleeding while taking protease inhibitors, such as atazanavir powder for oral suspension. Report all bleeding episodes to the doctor.
  • Lab tests, including liver function, bilirubin levels, CD4 count, and lipid or cholesterol levels, may be performed while your child uses atazanavir powder for oral suspension. These tests may be used to monitor your child's condition or check for side effects. Be sure to keep all doctor and lab appointments.
  • Atazanavir powder for oral suspension should not be used in CHILDREN younger than 3 months old; a type of brain damage caused by high blood bilirubin levels (kernicterus) may occur.
  • Atazanavir powder for oral suspension should not be used in CHILDREN who weigh less than 22 lb (10 kg) or more than 55 lb (25 kg).
  • PREGNANCY and BREAST-FEEDING: If your child becomes pregnant, contact the doctor. You will need to discuss the benefits and risks of using atazanavir powder for oral suspension during pregnancy. It is not known if this medicine is found in breast milk. Mothers infected with HIV should not breast-feed. There is a risk of passing the HIV infection or atazanavir powder for oral suspension to the baby.

Possible side effects of atazanavir powder for oral suspension:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Cough; diarrhea; headache; mild stomach pain; muscle pain; nausea; stuffy or runny nose; trouble sleeping; vomiting.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); blood in the urine; burning, numbness, or tingling; dark urine; depression; dizziness; fever, chills, or sore throat; irregular heartbeat; light-headedness; painful urination; pale stools; persistent loss of appetite; red, swollen, blistered, or peeling skin; severe stomach or back pain (with or without nausea or vomiting); side pain; swelling of the hands, ankles, or feet; unusual bleeding or bruising; wheezing; yellowing of skin or eyes.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact the health care provider. Call the doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately.

Proper storage of atazanavir powder for oral suspension:

Store atazanavir powder for oral suspension at room temperature, below 86 degrees F (30 degrees C). Store away from heat, moisture, and light. Store in the original packet. Do not open it until you are ready to use. Do not store in the bathroom. Keep atazanavir powder for oral suspension out of the reach of children and away from pets.

General information:

  • If you have any questions about atazanavir powder for oral suspension, please talk with the doctor, pharmacist, or other health care provider.
  • Atazanavir powder for oral suspension is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your child's symptoms do not improve or if they become worse, check with the doctor.
  • Check with the pharmacist about how to dispose of unused medicine.

This information should not be used to decide whether or not to take atazanavir powder for oral suspension or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about atazanavir powder for oral suspension. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to atazanavir powder for oral suspension. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using atazanavir powder for oral suspension.

Review Date: November 3, 2016

Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.

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