Aspirin/ dipyridamole extended-release capsules
Generic Name: aspirin/dipyridamole (AS-pir-in/DYE-pir-ID-a-mole)
Brand Name: Aggrenox
Aspirin/ dipyridamole extended-release capsules are used for:
Reducing the risk of stroke in patients who have previously had a stroke due to a blood clot in the brain. It is also used to reduce the risk of stroke in patients who have had transient ischemic attacks (TIAs) (eg, "warning stroke" or "mini-stroke" that produces stroke-like symptoms but no lasting damage).
Aspirin/dipyridamole extended-release capsules are an antiplatelet combination. It works by preventing clots from forming in the blood.
Do NOT use aspirin/ dipyridamole extended-release capsules if:
- you are allergic to any ingredient in aspirin/dipyridamole extended-release capsules
- you have had a severe allergic reaction (eg, a severe rash, hives, breathing difficulties, dizziness) to aspirin or a nonsteroidal anti-inflammatory drug (NSAID) (eg, ibuprofen, naproxen, celecoxib)
- you have a certain bleeding problem (hemophilia) or low blood platelet levels, are actively bleeding, or have a history of peptic ulcer disease
- you have severe liver or kidney problems
- you have asthma in combination with a runny nose and certain growths in the nose (nasal polyps)
- you have received a varicella (chickenpox) vaccine within the past 6 weeks
- the patient is younger than 18 years old and has recently received certain influenza (flu) vaccines (live vaccines), or has the flu, chickenpox, or shingles
Contact your doctor or health care provider right away if any of these apply to you.
Before using aspirin/ dipyridamole extended-release capsules:
Some medical conditions may interact with aspirin/dipyridamole extended-release capsules. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
- if you are pregnant, planning to become pregnant, or are breast-feeding
- if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
- if you have allergies to medicines, foods, or other substances
- if you have a history of asthma; stomach or bowel problems (eg, ulcers); chest pain or heart problems (eg, heart blood vessel problems, heart attack); kidney problems; liver problems; low blood pressure; bleeding or clotting problems; myasthenia gravis; influenza (flu); chickenpox; shingles; hives, rash, or intense itching; Kawasaki syndrome; growths in the nose (nasal polyps); or vitamin K deficiency
- if you drink alcohol
Some MEDICINES MAY INTERACT with aspirin/dipyridamole extended-release capsules. Tell your health care provider if you are taking any other medicines, especially any of the following:
- Anticoagulants (eg, heparin, warfarin), other antiplatelet medicines (eg, anagrelide, clopidogrel), apixaban, dabigatran, desirudin, desvenlafaxine, NSAIDs (eg, celecoxib, naproxen), rivaroxaban, selective serotonin reuptake inhibitors (SSRIs) (eg, citalopram, sertraline), or venlafaxine because the risk of bleeding may be increased
- Adenosine, carbonic anhydrase inhibitors (eg, acetazolamide), methotrexate, oral antidiabetic medicines (eg, glyburide), or valproic acid because the risk of their side effects may be increased by aspirin/dipyridamole extended-release capsules
- Angiotensin-converting enzyme (ACE) inhibitors (eg, enalapril), beta-blockers (eg, propranolol), cholinesterase inhibitors (eg, pyridostigmine), diuretics (eg, furosemide, hydrochlorothiazide), phenytoin, probenecid, or sulfinpyrazone because their effectiveness may be decreased by aspirin/dipyridamole extended-release capsules
This may not be a complete list of all interactions that may occur. Ask your health care provider if aspirin/dipyridamole extended-release capsules may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.
How to use aspirin/ dipyridamole extended-release capsules:
Use aspirin/dipyridamole extended-release capsules as directed by your doctor. Check the label on the medicine for exact dosing instructions.
- An extra patient leaflet is available with aspirin/dipyridamole extended-release capsules. Talk to your pharmacist if you have questions about this information.
- Take aspirin/dipyridamole extended-release capsules by mouth with or without food.
- Swallow aspirin/dipyridamole extended-release capsules whole. Do not break, crush, or chew before swallowing.
- Take aspirin/dipyridamole extended-release capsules with a full glass of water (8 oz [240 mL]).
- Do not substitute this form of aspirin for any other aspirin or dipyridamole products. Discuss any questions or concerns with your doctor.
- If you miss a dose of aspirin/dipyridamole extended-release capsules, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.
Ask your health care provider any questions you may have about how to use aspirin/dipyridamole extended-release capsules.
Important safety information:
- Aspirin/dipyridamole extended-release capsules may cause dizziness. This effect may be worse if you take it with alcohol or certain medicines. Use aspirin/dipyridamole extended-release capsules with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
- Aspirin/dipyridamole extended-release capsules may cause dizziness or fainting. Alcohol, hot weather, exercise, and fever can increase these effects. To prevent them, sit up or stand slowly, especially in the morning. Sit or lie down at the first sign of any of these effects.
- Talk to your doctor before you take aspirin/dipyridamole extended-release capsules if you drink more than 3 drinks with alcohol per day. Serious stomach ulcers or bleeding can occur with the use of aspirin/dipyridamole extended-release capsules. Taking it in high doses or for a long time, smoking, or drinking alcohol increases the risk of these side effects. Taking aspirin/dipyridamole extended-release capsules with food will NOT reduce the risk of these effects. Contact your doctor or emergency room at once if you develop severe stomach or back pain; black, tarry stools; vomit that looks like blood or coffee grounds; or unusual weight gain or swelling.
- If headaches occur when you first start taking aspirin/dipyridamole extended-release capsules, they usually lessen as treatment continues. Tell your doctor if you have a severe or persistent headache. Your doctor may change how you take aspirin/dipyridamole extended-release capsules.
- Aspirin has been linked to a serious illness called Reye syndrome. Do not give aspirin/dipyridamole extended-release capsules to a child or teenager who has the flu, chickenpox, or a viral infection. Contact your doctor with any questions or concerns.
- Tell your doctor or dentist that you take aspirin/dipyridamole extended-release capsules before you receive any medical or dental care, emergency care, or surgery.
- Aspirin/dipyridamole extended-release capsules has aspirin in it. Before you start any new medicine, check the label to see if it has aspirin in it too. If it does or if you are not sure, check with your doctor or pharmacist.
- Diabetes patients - Aspirin/dipyridamole extended-release capsules may affect your blood sugar. Check blood sugar levels closely. Ask your doctor before you change the dose of your diabetes medicine.
- Use aspirin/dipyridamole extended-release capsules with caution in the ELDERLY; they may be more sensitive to its effects.
- Aspirin/dipyridamole extended-release capsules should not be used in CHILDREN; safety and effectiveness in children have not been confirmed.
- PREGNANCY and BREAST-FEEDING: Aspirin/dipyridamole extended-release capsules may cause harm to the fetus. Do not take it during the last 3 months of pregnancy. If you think you may be pregnant, contact your doctor. You will need to discuss the benefits and risks of using aspirin/dipyridamole extended-release capsules while you are pregnant. Aspirin/dipyridamole extended-release capsules are found in breast milk. If you are or will be breast-feeding while you use aspirin/dipyridamole extended-release capsules, check with your doctor. Discuss any possible risks to your baby.
Possible side effects of aspirin/ dipyridamole extended-release capsules:
All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:
Seek medical attention right away if any of these SEVERE side effects occur:
Diarrhea; dizziness; headache; heartburn; indigestion; mild stomach pain; nausea; upset stomach; vomiting.
Severe allergic reactions (rash; hives; itching; difficulty swallowing or breathing; tightness in the chest; swelling of the hands, mouth, face, lips, eyes, throat, or tongue; unusual hoarseness); blood in the urine; bloody or black, tarry stools; confusion; decreased urination; fainting; fast or irregular heartbeat; hearing loss; memory loss; new or worsening chest pain; one-sided weakness; red, swollen, blistered, or peeling skin; ringing in the ears; seizures; severe or persistent dizziness or light-headedness; severe or persistent headache (with or without drowsiness); severe or persistent heartburn, nausea, stomach pain, or vomiting; shortness of breath; slurred speech; symptoms of liver problems (eg, dark urine, itching, loss of appetite, pale stools, yellowing of the skin or eyes); unusual bruising or bleeding; unusual tiredness or weakness; vision changes; vomiting blood or vomit that looks like coffee grounds; wheezing.
This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.
If OVERDOSE is suspected:
Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include dizziness; fainting; fast heartbeat; flushing; restlessness; ringing in the ears; sweating; warm feeling; weakness.Proper storage of aspirin/dipyridamole extended-release capsules:
Store aspirin/dipyridamole extended-release capsules at room temperature, between 59 and 86 degrees F (15 and 30 degrees C) in a tightly closed container. Store away from heat, moisture, and light. Do not store in the bathroom. Keep aspirin/dipyridamole extended-release capsules out of the reach of children and away from pets.
- If you have any questions about aspirin/dipyridamole extended-release capsules, please talk with your doctor, pharmacist, or other health care provider.
- Aspirin/dipyridamole extended-release capsules are to be used only by the patient for whom it is prescribed. Do not share it with other people.
- If your symptoms do not improve or if they become worse, check with your doctor.
- Check with your pharmacist about how to dispose of unused medicine.
This information should not be used to decide whether or not to take aspirin/dipyridamole extended-release capsules or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about aspirin/dipyridamole extended-release capsules. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to aspirin/dipyridamole extended-release capsules. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using aspirin/dipyridamole extended-release capsules.
Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.
More about aspirin/dipyridamole
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- Drug class: platelet aggregation inhibitors
Other brands: Aggrenox