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Asparaginase Escherichia Coli

Generic Name: asparaginase (as-PAR-a-jin-ase)
Brand Name: Elspar

Asparaginase Escherichia Coli is used for:

Treating acute lymphocytic leukemia (ALL). It is used along with other cancer medicines.

Asparaginase Escherichia Coli is an antineoplastic agent. It works by decreasing the amount of asparagine in the body, which kills certain leukemia cells.

Do NOT use Asparaginase Escherichia Coli if:

  • you are allergic to any ingredient in Asparaginase Escherichia Coli or similar medicines
  • you have ever had serious blood clots, serious bleeding, or pancreatitis after using Asparaginase Escherichia Coli or similar medicines

Contact your doctor or health care provider right away if any of these apply to you.

Before using Asparaginase Escherichia Coli:

Some medical conditions may interact with Asparaginase Escherichia Coli. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have liver problems, bone marrow problems, diabetes or high blood sugar, or an infection
  • if you have a history of bleeding problems or blood clots

Some MEDICINES MAY INTERACT with Asparaginase Escherichia Coli. However, no specific interactions with Asparaginase Escherichia Coli are known at this time.

This may not be a complete list of all interactions that may occur. Ask your health care provider if Asparaginase Escherichia Coli may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Asparaginase Escherichia Coli:

Use Asparaginase Escherichia Coli as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Asparaginase Escherichia Coli is usually given as an injection at your doctor's office, hospital, or clinic.
  • Do not use Asparaginase Escherichia Coli if it contains particles, is cloudy or discolored, or if the vial is cracked or damaged.
  • Keep this product, as well as syringes and needles, out of the reach of children and away from pets. Do not reuse needles, syringes, or other materials. Dispose of properly after use. Ask your doctor or pharmacist to explain local regulations for proper disposal.
  • If you miss a dose of Asparaginase Escherichia Coli, contact your doctor immediately.

Ask your health care provider any questions you may have about how to use Asparaginase Escherichia Coli.

Important safety information:

  • Serious bleeding and blood clots have been reported with the use of Asparaginase Escherichia Coli and other similar medicines. Contact your doctor right away if you experience calf, leg, or arm pain, swelling, redness, or tenderness; chest pain; coughing up blood; one-sided weakness; shortness of breath; slurred speech; unusual bruising or bleeding; or vision problems.
  • Do not receive a live vaccine (eg, measles, mumps) while you are taking Asparaginase Escherichia Coli. Talk with your doctor before you receive any vaccine.
  • Asparaginase Escherichia Coli may cause a certain brain or nervous system problem called posterior reversible encephalopathy syndrome (PRES). Tell your doctor right away if you notice symptoms of PRES (eg, confusion, severe or persistent headache or dizziness, seizures, vision changes).
  • Tell your doctor or dentist that you take Asparaginase Escherichia Coli before you receive any medical or dental care, emergency care, or surgery.
  • Asparaginase Escherichia Coli may raise your blood sugar. High blood sugar may make you feel confused, drowsy, or thirsty. It can also make you flush, breathe faster, or have a fruit-like breath odor. If these symptoms occur, tell your doctor right away.
  • Diabetes patients - Check blood sugar levels closely and ask your doctor before adjusting the dose of your diabetes medicine.
  • Lab tests, including blood clotting tests, liver function, or blood glucose, may be performed while you use Asparaginase Escherichia Coli. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
  • PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Asparaginase Escherichia Coli while you are pregnant. It is not known if this medicine is found in breast milk. Do not breast-feed while taking Asparaginase Escherichia Coli.

Possible side effects of Asparaginase Escherichia Coli:

All medicines may cause side effects, but many people have no, or minor, side effects. No COMMON side effects have been reported with Asparaginase Escherichia Coli. Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); fever; pain, redness, or swelling at the injection site; symptoms of liver problems (eg, dark urine, pale stools, nausea, loss of appetite, unusual tiredness, yellowing of the skin or eyes); symptoms of pancreatitis (eg, severe stomach or back pain with or without nausea or vomiting).

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.

See also: Side effects (in more detail)

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org), or emergency room immediately.

Proper storage of Asparaginase Escherichia Coli:

Asparaginase Escherichia Coli is usually handled and stored by a health care provider. Keep Asparaginase Escherichia Coli out of the reach of children and away from pets.

General information:

  • If you have any questions about Asparaginase Escherichia Coli, please talk with your doctor, pharmacist, or other health care provider.
  • Asparaginase Escherichia Coli is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.
  • Check with your pharmacist about how to dispose of unused medicine.

This information should not be used to decide whether or not to take Asparaginase Escherichia Coli or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about Asparaginase Escherichia Coli. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to Asparaginase Escherichia Coli. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using Asparaginase Escherichia Coli.

Review Date: November 3, 2016

Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.

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