Aptivus (Oral Solution)
Generic Name: Tipranavir Oral Solution (tye PRAN a vir)
Brand Name: Aptivus
- Rare reports of bleeding into the brain have happened. Harm to the liver has also happened. Sometimes these side effects have been deadly. Patients with hepatitis B or C may have more chance of liver problems. Talk with the doctor.
Uses of Aptivus:
- It is used to treat HIV infection.
What do I need to tell my doctor BEFORE I take Aptivus?
For all patients taking this medicine (Aptivus):
- If you have an allergy to tipranavir or any other part of this medicine (Aptivus).
- If you are allergic to any drugs like this one, any other drugs, foods, or other substances. Tell your doctor about the allergy and what signs you had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
- If you are not taking ritonavir.
- If you have liver disease.
- If you are taking St. John's wort. Do not take St. John's wort with this medicine (Aptivus). This medicine may not work as well.
- If you take any drugs (prescription or OTC, natural products, vitamins) that must not be taken with this medicine (Aptivus), like certain drugs that are used for high cholesterol, migraines, or mood problems. There are many drugs that must not be taken with this medicine (Aptivus).
- If you are breast-feeding. Do not breast-feed while you take this medicine (Aptivus).
- If your child is younger than 2 years of age. Do not give this medicine (Aptivus) to a child younger than 2 years of age.
This is not a list of all drugs or health problems that interact with this medicine (Aptivus).
Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take this medicine (Aptivus) with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.
What are some things I need to know or do while I take Aptivus?
- Tell all of your health care providers that you take this medicine (Aptivus). This includes your doctors, nurses, pharmacists, and dentists.
- This medicine interacts with many other drugs. The chance of this medicine (Aptivus)'s side effects may be raised or how well this medicine (Aptivus) works may be lowered. The chance of the other drugs' side effects may also be raised. This may include very bad, life-threatening, or deadly side effects. Check with your doctor and pharmacist to make sure that it is safe for you to take this medicine (Aptivus) with all of your other drugs (prescription or OTC, natural products, vitamins).
- If you have high blood sugar (diabetes), talk with your doctor. This medicine may raise blood sugar.
- Some people with hemophilia have had times of more bleeding when taking drugs like this one. If you have hemophilia, talk with your doctor.
- This medicine may cause high cholesterol and triglyceride levels. Talk with the doctor.
- Have blood work checked as you have been told by the doctor. Talk with the doctor.
- This medicine is not a cure for HIV. Stay under the care of your doctor.
- You may get sunburned more easily. Avoid sun, sunlamps, and tanning beds. Use sunscreen and wear clothing and eyewear that protects you from the sun.
- This medicine does not stop the spread of diseases like HIV or hepatitis that are passed through blood or having sex. Do not have any kind of sex without using a latex or polyurethane condom. Do not share needles or other things like toothbrushes or razors. Talk with your doctor.
- Birth control pills and other hormone-based birth control may not work as well to prevent pregnancy. Use some other kind of birth control also like a condom when taking this medicine (Aptivus).
- If you are 65 or older, use this medicine (Aptivus) with care. You could have more side effects.
- Use with care in children. Talk with the doctor.
- Tell your doctor if you are pregnant or plan on getting pregnant. You will need to talk about the benefits and risks of using this medicine (Aptivus) while you are pregnant.
How is this medicine (Aptivus) best taken?
Use this medicine (Aptivus) as ordered by your doctor. Read all information given to you. Follow all instructions closely.
- Measure liquid doses carefully. Use the measuring device that comes with this medicine (Aptivus). If there is none, ask the pharmacist for a device to measure this medicine (Aptivus).
- Talk with your doctor before you take other sources of vitamin E. This medicine has vitamin E in it.
- This medicine must be taken with another drug called ritonavir. If you take ritonavir capsules or liquid (solution), take this medicine (Aptivus) with or without meals. If you take ritonavir tablets, take this medicine (Aptivus) with meals.
- Do not take didanosine within 2 hours of this medicine (Aptivus).
- Keep taking this medicine (Aptivus) as you have been told by your doctor or other health care provider, even if you feel well.
- It is important that you do not miss or skip a dose of this medicine (Aptivus) during treatment.
What do I do if I miss a dose?
- Take a missed dose as soon as you think about it.
- If it is close to the time for your next dose, skip the missed dose and go back to your normal time.
- Do not take 2 doses at the same time or extra doses.
- If you are not sure what to do if you miss a dose, call your doctor.
See also: Dosage Information (in more detail)
What are some side effects that I need to call my doctor about right away?
WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:
- Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
- Signs of liver problems like dark urine, feeling tired, not hungry, upset stomach or stomach pain, light-colored stools, throwing up, or yellow skin or eyes.
- Signs of high blood sugar like confusion, feeling sleepy, more thirst, more hungry, passing urine more often, flushing, fast breathing, or breath that smells like fruit.
- Weakness on 1 side of the body, trouble speaking or thinking, change in balance, drooping on one side of the face, or blurred eyesight.
- Muscle or joint pain.
- Any unexplained bruising or bleeding.
- Change in body fat.
- This medicine may help the immune system work. If you have an infection that you did not know you had, it may show up when you take this medicine (Aptivus). Tell your doctor right away if you notice any signs of infection like fever, sore throat, weakness, cough, or shortness of breath after you start this medicine (Aptivus).
What are some other side effects of Aptivus?
All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:
These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.
You may report side effects to the FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.
See also: Side effects (in more detail)
If OVERDOSE is suspected:
If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
How do I store and/or throw out Aptivus?
- Store at room temperature. Do not refrigerate or freeze.
- After opening, throw away any part not used after 60 days.
- Store in a dry place. Do not store in a bathroom.
- Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
- Throw away unused or expired drugs. Do not flush down a toilet or pour down a drain unless you are told to do so. Check with your pharmacist if you have questions about the best way to throw out drugs. There may be drug take-back programs in your area.
Consumer Information Use and Disclaimer
- If your symptoms or health problems do not get better or if they become worse, call your doctor.
- Do not share your drugs with others and do not take anyone else's drugs.
- Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
- Talk with the doctor before starting any new drug, including prescription or OTC, natural products, or vitamins.
- Some drugs may have another patient information leaflet. Check with your pharmacist. If you have any questions about this medicine (Aptivus), please talk with your doctor, nurse, pharmacist, or other health care provider.
- If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
Disclaimer: This information should not be used to decide whether or not to take this medicine (Aptivus) or any other medicine. Only the healthcare provider has the knowledge and training to decide which medicines are right for a specific patient. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine (Aptivus). It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine (Aptivus). This information is not specific medical advice and does not replace information you receive from the healthcare provider. You must talk with the healthcare provider for complete information about the risks and benefits of using this medicine (Aptivus).
Review Date: March 7, 2018
More about Aptivus (tipranavir)
- Side Effects
- During Pregnancy or Breastfeeding
- Dosage Information
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- Drug Interactions
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- Drug class: protease inhibitors