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Apomorphine Cartridges and Pens

Generic Name: Apomorphine Cartridges and Pens (a poe MOR feen)
Brand Name: Apokyn

Uses of Apomorphine Cartridges and Pens:

  • It is used to treat Parkinson's disease.

What do I need to tell my doctor BEFORE I take Apomorphine Cartridges and Pens?

  • If you have an allergy to apomorphine or any other part of this medicine (apomorphine cartridges and pens).
  • If you are allergic to any drugs like this one, any other drugs, foods, or other substances. Tell your doctor about the allergy and what signs you had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
  • If you are taking any of these drugs: Alosetron, dolasetron, granisetron, ondansetron, or palonosetron.

This is not a list of all drugs or health problems that interact with this medicine.

Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take this medicine (apomorphine cartridges and pens) with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.

What are some things I need to know or do while I take Apomorphine Cartridges and Pens?

  • Tell all of your health care providers that you take this medicine. This includes your doctors, nurses, pharmacists, and dentists.
  • Avoid driving and doing other tasks or actions that call for you to be alert until you see how this medicine (apomorphine cartridges and pens) affects you.
  • To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down. Be careful going up and down stairs.
  • Do not stop taking this medicine all of a sudden without calling your doctor. You may have a greater risk of side effects. If you need to stop this medicine (apomorphine cartridges and pens), you will want to slowly stop it as ordered by your doctor.
  • Avoid drinking alcohol while taking this medicine.
  • Talk with your doctor before you use other drugs and natural products that slow your actions.
  • Have blood work checked as you have been told by the doctor. Talk with the doctor.
  • Check blood pressure and heart rate as the doctor has told you. Talk with the doctor.
  • If you are allergic to sulfites, talk with your doctor. Some products have sulfites.
  • Do not give this medicine (apomorphine cartridges and pens) as a shot into a vein. Blood clots (in the lungs) have happened when this medicine was given as a shot into a vein. Talk with your doctor.
  • An unsafe heartbeat that is not normal (long QT on ECG) has happened with this medicine (apomorphine cartridges and pens). Chest pain, heart attack, and sudden deaths have also rarely happened in people taking this medicine. Talk with the doctor.
  • The chance of a type of skin cancer called melanoma may be raised in people with Parkinson's disease. It is not known if this medicine (apomorphine cartridges and pens) may also raise the chance. Have skin exams while you take this medicine. Talk with your doctor.
  • Other drugs will be given with this medicine (apomorphine cartridges and pens) to help avoid side effects.
  • The chance of falling is raised with this medicine. Falls may lead to very bad problems like head injury and broken bones. The chance of falling is higher in older people. Talk with the doctor.
  • Call your doctor right away if you have a painful erection (hard penis) or an erection that lasts for longer than 4 hours. This may happen even when you are not having sex. If this is not treated right away, it may lead to lasting sex problems and you may not be able to have sex.
  • Do not share pen or cartridge devices with another person even if the needle has been changed. Sharing these devices may pass infections from one person to another. This includes infections you may not know you have.
  • If you are 65 or older, use this medicine (apomorphine cartridges and pens) with care. You could have more side effects.
  • Tell your doctor if you are pregnant or plan on getting pregnant. You will need to talk about the benefits and risks of using this medicine while you are pregnant.
  • Tell your doctor if you are breast-feeding. You will need to talk about any risks to your baby.

How is this medicine (Apomorphine Cartridges and Pens) best taken?

Use this medicine (apomorphine cartridges and pens) as ordered by your doctor. Read all information given to you. Follow all instructions closely.

  • It is given as a shot into the fatty part of the skin.
  • If you will be giving yourself the shot, your doctor or nurse will teach you how to give the shot.
  • Follow how to use as you have been told by the doctor or read the package insert.
  • Do not use if the solution is cloudy, leaking, or has particles.
  • Do not use if solution changes color.
  • Wash your hands before and after use.
  • Move the site where you give the shot with each shot.
  • Do not give into red or irritated skin.
  • Throw away needles in a needle/sharp disposal box. Do not reuse needles or other items. When the box is full, follow all local rules for getting rid of it. Talk with a doctor or pharmacist if you have any questions.
  • If it has been more than 7 days since your last dose, call your doctor to find out how to restart.

What do I do if I miss a dose?

  • Call your doctor to find out what to do.

Dosage Information (comprehensive)

What are some side effects that I need to call my doctor about right away?

WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:

  • Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
  • Signs of a urinary tract infection (UTI) like blood in the urine, burning or pain when passing urine, feeling the need to pass urine often or right away, fever, lower stomach pain, or pelvic pain.
  • Signs of dehydration like dry skin, mouth, or eyes; thirst; fast heartbeat; dizziness; fast breathing; or confusion.
  • Weakness on 1 side of the body, trouble speaking or thinking, change in balance, drooping on one side of the face, or blurred eyesight.
  • Very bad dizziness or passing out.
  • Feeling confused.
  • Very upset stomach or throwing up.
  • A skin lump or growth.
  • Change in color or size of a mole.
  • Strong urges that are hard to control (such as eating, gambling, sex, or spending money).
  • Mood changes.
  • Change in the way you act.
  • Trouble controlling body movements that is new or worse.
  • Hallucinations (seeing or hearing things that are not there).
  • Sweating a lot.
  • A heartbeat that does not feel normal.
  • Shortness of breath, a big weight gain, or swelling in the arms or legs.
  • Chest pain or pressure or a fast heartbeat.
  • Bruising or dark areas of skin.
  • Some people have fallen asleep during activities like driving, eating, or talking. Some people did not feel sleepy and felt alert right before falling asleep. This has happened up to 1 year after this medicine was started. If you fall asleep during activities, do not drive or do other tasks or actions that call for you to be alert while you take this medicine (apomorphine cartridges and pens). Call your doctor right away if this happens or you feel very sleepy.

What are some other side effects of Apomorphine Cartridges and Pens?

All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:

  • Upset stomach or throwing up.
  • Runny nose.
  • Yawning.
  • Irritation where the shot is given.
  • Dizziness.
  • Feeling sleepy.
  • Headache.
  • Joint pain.
  • Not able to sleep.
  • Back pain.
  • Feeling tired or weak.
  • Hard stools (constipation).
  • Loose stools (diarrhea).

These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.

You may report side effects to the FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.

Side Effects (complete list)

If OVERDOSE is suspected:

If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

How do I store and/or throw out Apomorphine Cartridges and Pens?

  • Store at room temperature.
  • Follow how to store closely. Read the package insert that comes with this medicine. If you have questions about how to store this medicine (apomorphine cartridges and pens), talk with your pharmacist.
  • Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
  • Check with your pharmacist about how to throw out unused drugs.

Consumer Information Use and Disclaimer

  • If your symptoms or health problems do not get better or if they become worse, call your doctor.
  • Do not share your drugs with others and do not take anyone else's drugs.
  • Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
  • Talk with the doctor before starting any new drug, including prescription or OTC, natural products, or vitamins.
  • Some drugs may have another patient information leaflet. Check with your pharmacist. If you have any questions about this medicine, please talk with your doctor, nurse, pharmacist, or other health care provider.
  • If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

This information should not be used to decide whether or not to take this medicine (apomorphine cartridges and pens) or any other medicine. Only the healthcare provider has the knowledge and training to decide which medicines are right for a specific patient. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine (apomorphine cartridges and pens). This information is not specific medical advice and does not replace information you receive from the healthcare provider. You must talk with the healthcare provider for complete information about the risks and benefits of using this medicine.

Review Date: December 6, 2017

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