Generic Name: amphetamine (am-FET-a-meen)
Brand Name: Evekeo
Amphetamine has a high potential for abuse and may be habit-forming if used for a long period of time. Use amphetamine only as prescribed. Do not share it with others. Abuse of amphetamine may cause serious heart problems, blood vessel problems, or sudden death.
Amphetamine is used for:
Treating attention deficit hyperactivity disorder (ADHD). It is also used to treat a type of sleep disorder (narcolepsy). It is also used on short-term basis (a few weeks) in combination with other treatments to treat obesity. It may also be used for other conditions as determined by your doctor.
Amphetamine is a central nervous system stimulant. Exactly how it works is not known. It affects certain chemicals in the brain, which may help to improve attention span and behavior.
Do NOT use amphetamine if:
- you are allergic to any ingredient in amphetamine or to similar medicines
- you have severe hardening of the arteries; active heart or blood vessel disease; moderate, severe, or uncontrolled high blood pressure; or an overactive thyroid
- you have agitation, anxiety, or tension
- you take or have taken furazolidone or a monoamine oxidase inhibitor (MAOI) (eg, phenelzine) within the last 14 days
- you have a history of drug abuse
Contact your doctor or health care provider right away if any of these apply to you.
Before using amphetamine:
Some medical conditions may interact with amphetamine. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
- if you are pregnant, planning to become pregnant, or are breast-feeding
- if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
- if you have allergies to medicines, foods, or other substances
- if you or a family member have a history of mental or mood problems (eg, bipolar disorder, depression, psychosis), uncontrolled muscle movements (eg, tics), Tourette syndrome, or suicidal thoughts or attempts
- if you have a history of heart problems (eg, heart failure, heart rhythm problems, heart defect), high blood pressure, seizures, abnormal electroencephalogram (EEG) test, growth problems, thyroid problems, glaucoma, hardening of the arteries, or blood vessel problems, or you have had a recent heart attack
- if you have a family history of sudden death or heart rhythm problems
- if you have circulation problems in your hands or feet (eg, Raynaud phenomenon, thromboangiitis obliterans)
- if you are taking an antihistamine (eg, diphenhydramine) to help you sleep
Some MEDICINES MAY INTERACT with amphetamine. Tell your health care provider if you are taking any other medicines, especially any of the following:
- Acetazolamide, propoxyphene, sodium bicarbonate, or thiazide diuretics (eg, hydrochlorothiazide) because they may increase the risk of amphetamine's side effects
- Ethosuximide or or medicine for high blood pressure because their effectiveness may be decreased by amphetamine
- Ammonium chloride, ascorbic acid (vitamin C), chlorpromazine, glutamic acid, guanethidine, haloperidol, lithium carbonate, methenamine, reserpine, or sodium acid phosphate because they may decrease amphetamine's effectiveness
- Furazolidone or MAOIs (eg, phenelzine) because the risk of severe high blood pressure, fever, headache, and decreased heart rate may be increased
- Meperidine, phenobarbital, phenytoin, sympathomimetics (eg, pseudoephedrine), or tricyclic antidepressants (eg, desipramine) because the risk of their side effects may be increased by amphetamine
This may not be a complete list of all interactions that may occur. Ask your health care provider if amphetamine may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.
How to use amphetamine:
Use amphetamine as directed by your doctor. Check the label on the medicine for exact dosing instructions.
- Amphetamine comes with an extra patient information sheet called a Medication Guide. Read it carefully. Read it again each time you get amphetamine refilled.
- Take amphetamine by mouth with or without food.
- Take your doses of amphetamine 4 to 6 hours apart unless your doctor tells you otherwise.
- Do not drink fruit juice at the same time that you take amphetamine. Certain fruit juices (eg, grapefruit, apple, orange) may decrease amphetamine's effectiveness.
- Take amphetamine on a regular schedule to get the most benefit from it. Taking amphetamine at the same time each day will help you remember to take it.
- If you miss a dose of amphetamine, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.
Ask your health care provider any questions you may have about how to use amphetamine.
Important safety information:
- Tell your doctor or dentist that you take amphetamine before you receive any medical or dental care, emergency care, or surgery.
- Amphetamine may cause dizziness. This effect may be worse if you take it with alcohol or certain medicines. Use amphetamine with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
- Do NOT take more than the recommended dose or use for longer than prescribed without checking with your doctor.
- Serious effects, including heart attack, stroke, and sudden death, have occurred with the use of stimulant medicines in patients with heart defects or other serious heart problems. If you have a heart defect or other serious heart problem, talk with your doctor about other therapies to treat your condition.
- Amphetamine may cause sleeplessness. Do not take amphetamine near your bedtime unless your doctor tells you otherwise.
- Amphetamine may cause circulation problems in the hands and feet. Tell your doctor if you have any numbness, pain, tingling, cold feeling, or skin color change (eg, from pale to blue or red) in your hands or feet. Call your doctor right away if you have any unexplained sores or wounds on your fingers or toes.
- Amphetamine may interfere with certain lab tests. Be sure your doctor and lab personnel know you are taking amphetamine.
- You may need to have some heart tests before starting amphetamine. Discuss any questions or concerns with your doctor.
- Check your blood pressure and heart rate as your doctor has told you. Discuss any questions or concerns with your doctor.
- Lab tests may be performed while you use amphetamine. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
- Amphetamine should not be used in CHILDREN younger than 3 years old; safety and effectiveness in these children have not been confirmed.
- Amphetamine may affect growth rate in CHILDREN and teenagers in some cases. They may need regular growth checks while they take amphetamine.
- PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using amphetamine while you are pregnant. Amphetamine is found in breast milk. Do not breast-feed while taking amphetamine.
When used for long periods of time or at high doses, amphetamine may not work as well and may require higher doses to obtain the same effect as when originally taken. This is known as TOLERANCE. Talk with your doctor if amphetamine stops working well. Do not take more than prescribed.
Some people who use amphetamine for a long time may develop a need to continue taking it. People who take high doses are also at risk. This is known as DEPENDENCE or addiction. If you suddenly stop taking amphetamine, you may experience WITHDRAWAL symptoms. These may include severe fatigue and drowsiness.
Possible side effects of amphetamine:
All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:
Seek medical attention right away if any of these SEVERE side effects occur:
Constipation; diarrhea; dizziness; dry mouth; feeling nervous or excited; headache; loss of appetite; nausea; restlessness; trouble sleeping; unpleasant taste; upset stomach; vomiting; weight loss.
Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); blurred vision or other vision changes; change in sexual ability or desire; chest pain or tightness; erections that happen often or that last a long time; fainting; fast or irregular heartbeat; hallucinations; new or worsening mental, mood, or behavior changes (eg, aggression, depression, hostility); seizures; severe or persistent dizziness or headache; shortness of breath; symptoms of stroke (eg, confusion, one-sided weakness, slurred speech); tremor; uncontrolled speech or muscle movements (eg, tics).
This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.
If OVERDOSE is suspected:
Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately.Proper storage of amphetamine:
Store amphetamine at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep amphetamine out of the reach of children and away from pets.
- If you have any questions about amphetamine, please talk with your doctor, pharmacist, or other health care provider.
- Amphetamine is to be used only by the patient for whom it is prescribed. Do not share it with other people.
- If your symptoms do not improve or if they become worse, check with your doctor.
- Check with your pharmacist about how to dispose of unused medicine.
This information should not be used to decide whether or not to take amphetamine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about amphetamine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to amphetamine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using amphetamine.
Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.
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- Drug class: CNS stimulants