Acetaminophen/ dextromethorphan/ guaifenesin/ phenylephrine liquid
Generic Name: acetaminophen/dextromethorphan/guaifenesin/phenylephrine (a-SEET-a-MIN-oh-fen/DEX-troe-meth-OR-fan/gwye-FEN-e-sin/FEN-il-EF-rin)
Brand Name: Examples include Delsym Cough + Cold Daytime and Tylenol Cold Multi-Symptom Daytime
Acetaminophen/ dextromethorphan/ guaifenesin/ phenylephrine liquid is used for:
Relieving pain, fever, congestion, cough, and throat and airway irritation due to colds, flu, or hay fever. It may also be used for other conditions as determined by your doctor.
Acetaminophen/dextromethorphan/guaifenesin/phenylephrine liquid is an analgesic, decongestant, cough suppressant, and expectorant combination. It works by constricting blood vessels and reducing swelling in the nasal passages, loosening mucus and lung secretions in the chest, and making coughs more productive. The analgesic and cough suppressant works in the brain to decrease pain and to help decrease the cough reflex to reduce a dry cough.
Do NOT use acetaminophen/ dextromethorphan/ guaifenesin/ phenylephrine liquid if:
- you are allergic to any ingredient in acetaminophen/dextromethorphan/guaifenesin/phenylephrine liquid
- you have severe high blood pressure, rapid heartbeat, severe heart blood vessel disease, or other severe heart problems
- you are taking another medicine that contains acetaminophen
- you have taken furazolidone or a monoamine oxidase inhibitor (MAOI) (eg, phenelzine) within the last 14 days
Contact your doctor or health care provider right away if any of these apply to you.
Before using acetaminophen/ dextromethorphan/ guaifenesin/ phenylephrine liquid:
Some medical conditions may interact with acetaminophen/dextromethorphan/guaifenesin/phenylephrine liquid. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
- if you are pregnant, planning to become pregnant, or are breast-feeding
- if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
- if you have allergies to medicines, foods, or other substances
- if you have a history of glaucoma, an enlarged prostate or other prostate problems, heart problems, diabetes, high blood pressure, blood vessel problems, adrenal gland problems, thyroid problems, seizures, stroke, liver problems, or kidney problems
- if you have a history of asthma, chronic cough, lung problems (eg, chronic bronchitis, emphysema), or chronic obstructive pulmonary disease (COPD), or if your cough occurs with large amounts of mucus
- if you smoke, drink alcohol, or have a history of addiction to alcohol
Some MEDICINES MAY INTERACT with acetaminophen/dextromethorphan/guaifenesin/phenylephrine liquid. Tell your health care provider if you are taking any other medicines, especially any of the following:
- Beta-blockers (eg, propranolol), catechol-O-methyltransferase (COMT) inhibitors (eg, tolcapone), furazolidone, indomethacin, isoniazid, MAOIs (eg, phenelzine), or tricyclic antidepressants (eg, amitriptyline) because the risk of acetaminophen/dextromethorphan/guaifenesin/phenylephrine liquid's side effects may be increased
- Anticoagulants (eg, warfarin), digoxin, or droxidopa because the risk of side effects such as bleeding, irregular heartbeat, or heart attack may be increased
- Bromocriptine because the risk of its side effects may be increased by acetaminophen/dextromethorphan/guaifenesin/phenylephrine liquid
- Guanadrel, guanethidine, mecamylamine, methyldopa, or reserpine because their effectiveness may be decreased by acetaminophen/dextromethorphan/guaifenesin/phenylephrine liquid
This may not be a complete list of all interactions that may occur. Ask your health care provider if acetaminophen/dextromethorphan/guaifenesin/phenylephrine liquid may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.
How to use acetaminophen/ dextromethorphan/ guaifenesin/ phenylephrine liquid:
Use acetaminophen/dextromethorphan/guaifenesin/phenylephrine liquid as directed by your doctor. Check the label on the medicine for exact dosing instructions.
- Take acetaminophen/dextromethorphan/guaifenesin/phenylephrine liquid by mouth with or without food.
- Use a measuring device marked for medicine dosing. Ask your pharmacist for help if you are unsure of how to measure your dose.
- Drink plenty of water while taking acetaminophen/dextromethorphan/guaifenesin/phenylephrine liquid.
- If you miss a dose of acetaminophen/dextromethorphan/guaifenesin/phenylephrine liquid and you are taking it regularly, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.
Ask your health care provider any questions you may have about how to use acetaminophen/dextromethorphan/guaifenesin/phenylephrine liquid.
Important safety information:
- Acetaminophen/dextromethorphan/guaifenesin/phenylephrine liquid may cause drowsiness or dizziness. These effects may be worse if you take it with alcohol or certain medicines. Use acetaminophen/dextromethorphan/guaifenesin/phenylephrine liquid with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
- Do not take appetite suppressants while you use acetaminophen/dextromethorphan/guaifenesin/phenylephrine liquid unless your doctor tells you otherwise.
- Acetaminophen/dextromethorphan/guaifenesin/phenylephrine liquid contains acetaminophen, dextromethorphan, guaifenesin, and phenylephrine. Before you start any new medicine, check the label to see if it has any of these medicines or similar medicines in it. If it does or if you are not sure, check with your doctor or pharmacist.
- Contact your doctor right away if you take more than 4,000 mg of acetaminophen per day, even if you feel well.
- Do not use acetaminophen/dextromethorphan/guaifenesin/phenylephrine liquid for a cough with a lot of mucous. Do not use it for a long-term cough (eg, caused by asthma, emphysema, smoking). However, you may use it for these conditions if your doctor tells you to.
- Do NOT take more than the recommended dose or use for longer than prescribed without checking with your doctor.
- If your symptoms do not get better within 7 days or if they get worse, check with your doctor.
- If you have a fever that becomes worse or lasts for more than 3 days, contact your doctor.
- Contact your doctor if you have a sore throat that becomes severe, lasts for more than 2 days, or occurs with fever, headache, rash, nausea, or vomiting.
- Contact your doctor if your cough comes back or occurs with fever, rash, or persistent headache.
- Acetaminophen/dextromethorphan/guaifenesin/phenylephrine liquid may harm your liver. Your risk may be greater if you drink alcohol while you are using acetaminophen/dextromethorphan/guaifenesin/phenylephrine liquid. Talk to your doctor before you take acetaminophen/dextromethorphan/guaifenesin/phenylephrine liquid or other fever reducers if you drink alcohol.
- A very bad skin reaction (Stevens-Johnson syndrome/toxic epidermal necrolysis) may happen. It can cause very bad health problems that may not go away and sometimes death. Get medical help right away if you have signs like red, swollen, blistered, or peeling skin (with or without fever); red or irritated eyes; or sores in your mouth, throat, nose, or eyes.
- Some brands of acetaminophen/dextromethorphan/guaifenesin/phenylephrine liquid contain sodium. If you are on a low-salt diet, ask your pharmacist if your brand contains sodium.
- Acetaminophen/dextromethorphan/guaifenesin/phenylephrine liquid may interfere with certain lab tests. Be sure your doctor and lab personnel know you are taking acetaminophen/dextromethorphan/guaifenesin/phenylephrine liquid.
- Tell your doctor or dentist that you take acetaminophen/dextromethorphan/guaifenesin/phenylephrine liquid before you receive any medical or dental care, emergency care, or surgery.
- Use acetaminophen/dextromethorphan/guaifenesin/phenylephrine liquid with caution in the ELDERLY; they may be more sensitive to its effects.
- Caution is advised when using acetaminophen/dextromethorphan/guaifenesin/phenylephrine liquid in CHILDREN; they may be more sensitive to its effects.
- Different brands of acetaminophen/dextromethorphan/guaifenesin/phenylephrine liquid may have different dosing instructions for CHILDREN. Follow the dosing instructions on the package labeling. If your doctor has given you instructions, follow those. If you are unsure of the dose to give a child, check with your doctor or pharmacist.
- PREGNANCY and BREAST-FEEDING: It is not known if acetaminophen/dextromethorphan/guaifenesin/phenylephrine liquid can cause harm to the fetus. If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using acetaminophen/dextromethorphan/guaifenesin/phenylephrine liquid while you are pregnant. It is not known if this medicine is found in breast milk. Do not breast-feed while taking acetaminophen/dextromethorphan/guaifenesin/phenylephrine liquid.
Possible side effects of acetaminophen/ dextromethorphan/ guaifenesin/ phenylephrine liquid:
All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome: Check with your doctor if any of these most COMMON side effects persist or become bothersome:
Seek medical attention right away if any of these SEVERE side effects occur:
Dizziness; drowsiness; excitability; headache; nausea; nervousness or anxiety; trouble sleeping.
Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); difficulty urinating; fast or irregular heartbeat; hallucinations; seizures; severe dizziness, light-headedness, or headache; symptoms of liver problems (eg, dark urine, pale stools, persistent loss of appetite, right-upper stomach pain, yellowing of the skin or eyes); tremor.
This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.
If OVERDOSE is suspected:
Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately.Proper storage of acetaminophen/dextromethorphan/guaifenesin/phenylephrine liquid:
Store acetaminophen/dextromethorphan/guaifenesin/phenylephrine liquid at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Do not refrigerate. Keep acetaminophen/dextromethorphan/guaifenesin/phenylephrine liquid out of the reach of children and away from pets.
- If you have any questions about acetaminophen/dextromethorphan/guaifenesin/phenylephrine liquid, please talk with your doctor, pharmacist, or other health care provider.
- Acetaminophen/dextromethorphan/guaifenesin/phenylephrine liquid is to be used only by the patient for whom it is prescribed. Do not share it with other people.
- If your symptoms do not improve or if they become worse, check with your doctor.
- Check with your pharmacist about how to dispose of unused medicine.
This information should not be used to decide whether or not to take acetaminophen/dextromethorphan/guaifenesin/phenylephrine liquid or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about acetaminophen/dextromethorphan/guaifenesin/phenylephrine liquid. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to acetaminophen/dextromethorphan/guaifenesin/phenylephrine liquid. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using acetaminophen/dextromethorphan/guaifenesin/phenylephrine liquid.
Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.
More about acetaminophen/dextromethorphan/guaifenesin/phenylephrine
- Side Effects
- During Pregnancy
- Dosage Information
- Drug Images
- Drug Interactions
- Support Group
- En Español
- 1 Review – Add your own review/rating
- Drug class: upper respiratory combinations
- Acetaminophen, dextromethorphan, guaifenesin, and phenylephrine