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Abraxane

Generic Name: Paclitaxel (Protein Bound) (pac li TAKS el PROE teen bownd)
Brand Name: Abraxane

Medically reviewed on Sep 5, 2018

Warning

  • This medicine may have unsafe effects on the bone marrow. The bone marrow may not be able to make cells found in the blood as well as it used to for a few weeks. This may raise the chance of bleeding or infection. Talk with the doctor.
  • This medicine must not be given to some people with low white blood cell counts. Talk with the doctor.
  • Have blood work checked as you have been told by the doctor. Talk with the doctor.
  • There is more than 1 brand of Abraxane (paclitaxel (protein bound)). One brand cannot safely be used for the other. The doctor will tell you about any needed change.

Uses of Abraxane:

See also: Kisqali
  • It is used to treat cancer.

What do I need to tell my doctor BEFORE I take Abraxane?

  • If you have an allergy to paclitaxel or any other part of Abraxane (paclitaxel (protein bound)).
  • If you are allergic to any drugs like this one, any other drugs, foods, or other substances. Tell your doctor about the allergy and what signs you had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
  • If you have liver disease.
  • If you are breast-feeding or plan to breast-feed.

This medicine may interact with other drugs or health problems.

Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take Abraxane (paclitaxel (protein bound)) with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.

What are some things I need to know or do while I take Abraxane?

  • Tell all of your health care providers that you take Abraxane (paclitaxel (protein bound)). This includes your doctors, nurses, pharmacists, and dentists.
  • Avoid driving and doing other tasks or actions that call for you to be alert until you see how Abraxane (paclitaxel (protein bound)) affects you.
  • Very bad and sometimes deadly allergic side effects have rarely happened. Talk with your doctor.
  • Other drugs may be given before Abraxane (paclitaxel (protein bound)) to help avoid side effects.
  • You may have more chance of getting an infection. Wash hands often. Stay away from people with infections, colds, or flu.
  • You may bleed more easily. Be careful and avoid injury. Use a soft toothbrush and an electric razor.
  • If you have upset stomach, throwing up, loose stools (diarrhea), or are not hungry, talk with your doctor. There may be ways to lower these side effects.
  • This medicine is made from human plasma (part of the blood) and may have viruses that may cause disease. This medicine is screened, tested, and treated to lower the chance that it carries an infection. Talk with the doctor.
  • Talk with your doctor before getting any vaccines. Use with Abraxane (paclitaxel (protein bound)) may either raise the chance of an infection or make the vaccine not work as well.
  • Talk with your doctor before you drink alcohol or use other drugs and natural products that slow your actions.
  • If you are 65 or older, use Abraxane (paclitaxel (protein bound)) with care. You could have more side effects.
  • Do not father a child while taking Abraxane (paclitaxel (protein bound)).
  • If you are a man and have sex with a female who could get pregnant, protect her from pregnancy. Use birth control that you can trust.
  • Use birth control that you can trust to prevent pregnancy while taking Abraxane (paclitaxel (protein bound)).
  • This medicine may cause harm to the unborn baby if you take it while you are pregnant. If you are pregnant or you get pregnant while taking Abraxane (paclitaxel (protein bound)), call your doctor right away.

How is this medicine (Abraxane) best taken?

Use Abraxane (paclitaxel (protein bound)) as ordered by your doctor. Read all information given to you. Follow all instructions closely.

  • It is given as an infusion into a vein over a period of time.

What do I do if I miss a dose?

  • Call your doctor to find out what to do.

What are some side effects that I need to call my doctor about right away?

WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:

  • Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
  • Signs of infection like fever, chills, very bad sore throat, ear or sinus pain, cough, more sputum or change in color of sputum, pain with passing urine, mouth sores, or wound that will not heal.
  • Signs of liver problems like dark urine, feeling tired, not hungry, upset stomach or stomach pain, light-colored stools, throwing up, or yellow skin or eyes.
  • Shortness of breath, a big weight gain, or swelling in the arms or legs.
  • Very bad dizziness or passing out.
  • Chest pain or pressure or a fast heartbeat.
  • Flushing.
  • A heartbeat that does not feel normal.
  • Slow heartbeat.
  • Very bad headache.
  • Very bad belly pain.
  • Very upset stomach or throwing up.
  • Very loose stools (diarrhea).
  • A burning, numbness, or tingling feeling that is not normal.
  • Any unexplained bruising or bleeding.
  • Nosebleed.
  • Feeling very tired or weak.
  • Very bad muscle or joint pain.
  • Change in eyesight.
  • Irritation where the shot is given.
  • This medicine may cause tissue damage if the drug leaks from the vein. Tell your nurse if you have any redness, burning, pain, swelling, blisters, skin sores, or leaking of fluid where the drug is going into your body.
  • Very bad and sometimes deadly lung problems have happened with Abraxane (paclitaxel (protein bound)). Call your doctor right away if you have lung or breathing problems like trouble breathing, shortness of breath, or a cough that is new or worse.

What are some other side effects of Abraxane?

All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:

  • Feeling tired or weak.
  • Mouth irritation or mouth sores.
  • Hair loss.
  • Upset stomach or throwing up.
  • Not hungry.
  • Loose stools (diarrhea).
  • Hard stools (constipation).
  • Muscle or joint pain.

These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.

You may report side effects to the FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

How do I store and/or throw out Abraxane?

  • If you need to store Abraxane (paclitaxel (protein bound)) at home, talk with your doctor, nurse, or pharmacist about how to store it.

Consumer information use

  • If your symptoms or health problems do not get better or if they become worse, call your doctor.
  • Do not share your drugs with others and do not take anyone else's drugs.
  • Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
  • Talk with the doctor before starting any new drug, including prescription or OTC, natural products, or vitamins.
  • Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
  • Throw away unused or expired drugs. Do not flush down a toilet or pour down a drain unless you are told to do so. Check with your pharmacist if you have questions about the best way to throw out drugs. There may be drug take-back programs in your area.
  • Some drugs may have another patient information leaflet. Check with your pharmacist. If you have any questions about Abraxane (paclitaxel (protein bound)), please talk with your doctor, nurse, pharmacist, or other health care provider.
  • If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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