I was put on Zyprexa in the hospital, and have continued the prescription for the past week that I have been Home from the hospital. While It's true that I have experienced an insatiable appetite, I am most concerned with the severe edema and the red, hot to the touch, skin on My calves and shins. This happened to me once before when taking another medication, and was subsequently diagnosed with allergic vasculitis. Has any one else experienced the extreme swelling, accompanied with bright red, hot to the touch, painful extremities?