I started Zoloft at 25mg to help with my anxiety and depression. It seemed to be working immediately. I woke up in the morning calmer and didn't feel the familiar suffocating feeling in my brain. It's also possible that after 5 years of therapy, I have made progress. After 2-3 weeks on Zoloft, the anxious feelings are back and I wonder if I need to go up to 50mg or perhaps it never was working, to begin with. Is it normal to see results so soon? Does the efficacy taper off each time the dose gets raised?