Hi-I started Zoloft 5 weeks ago, I jumped really fast. Started at 50 and went to 75 in a week and then 100 for two days and now I'm at 150. Basically been at 150 for 4 weeks and my hands seem shaky. It's not to the point of not being able to hold a cup but it's bothersome. Has anyone had this before? I'm also still feeling anxious, not as bad as before but not 100%. I'm on klonopin short term for sleep (it started with sleep and ectopic pregnancy) so I also had methotrexate about four weeks ago. Lots of fun stuff!! Any thoughts on what's causing the shakyness? My doctor said it really could be anything. Thoughts?