It's okay to take Zithromax with Tums. Ideally you would separate the doses by 2 hours.
Do not take antacids that contain aluminum or magnesium within 2 hours before or after you take azithromycin. This includes Rolaids, Maalox, Mylanta, Milk of Magnesia, Pepcid Complete, and others. These antacids can make azithromycin less effective when taken at the same time.
Tums contains calcium carbonate.
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