I am 51 years old and recently finished 5 or 6 months of Zenatane. At the end I noticed deep creases/lines on my chin and my skin seemed to have lost its elasticity and dropped. It gathers loose at my chin especially if I look down. The only thing I liked about having oily skin all my life was the fact that I didn't have wrinkles. I don't have oily skin any more, but now I have deep wrinkles.