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Should you take trazodone if you have kidney disease?

Responses (1)

WildcatVet 15 Jul 2018

Hi, Peggy! It depends on the type and severity of the kidney disease and should only be prescribed under a doctor's close supervision. Blood tests and dosage adjustments may be necessary.
"Moderate
Trazodone (Includes Trazodone) ↔ Renal/Liver Disease
Moderate Potential Hazard, Moderate plausibility

Applies to: Liver Disease, Renal Dysfunction

Trazodone undergoes metabolism in the liver. The metabolites, at least one of which is pharmacologically active, are excreted by the kidney. There are no data available concerning the pharmacokinetic disposition of trazodone or its metabolites in patients with renal and/or liver disease. Therapy with trazodone should be administered cautiously in patients with significantly impaired renal or hepatic function. Dosage adjustments may be necessary.

Best regards, Wildcat

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