How have you switched medication without feeling horrible? I’ve battled anxiety and depression since I was 17. I am now 42 and for once I would like to feel normal after years of so many normal episodes turning into bad depression. I was on Paxil for a few years and lately I was really depressed. My doctor put me on Wellbutrin 100 mg. I was to cut my Paxil in half for 5 days and take one Wellbutrin in the morning. and on the 6th day start taking another Wellbutrin in the evening. Yesterday I had no Paxil and had both doses of Wellbutrin. Today I felt awful, super tired, light-headed, and then super irritable. I figure I am coming off the Paxil, but I thought the Wellbutrin would offset the irritability and anxiety. I have Xanax, but only take them when I'm super anxious. I'd love some input from someone who has come off paxil to Wellbutrin. I am praying I do feel better soon, physically and emotionally.