I’ve been taking bupropion 300xl for about three months now. It was initially prescribed for slight depression and lack of energy due to other chronic illnesses. I asked my doctor for it so I could stop smoking as that flares my Crohn’s up. I have not been able to cut back on cigarettes. Recently a family friend told me that the only formula that would work for smoking secretion is the SR formula or to ask for Zyban by brand-name. My doctor did not want to initially prescribe the SR formula because of possible seizures. ( I have no history of seizures ) Any thoughts on thi I have not even been able to cut back on cigarettes. Recently a family friend told me that the only formula that would work for smoking secretion is the SR formula or to ask for Zyban by brand name. Any Information would be much appreciated.