I have to take this for 5 years. It's a anti hormone pill I know. And this is the only 1 so far, I can take with my Cimbalta. So far I'm having Nausea, cough, stool is ok so far. No stomach pains. A little joint pain just popped up from time to time. Someone recommend me to try Cryotherapy. But I just don't know about the long term affects with your nerves being in shock.my concern is will I have to take the Zofran until I'm done with the antil hormone therapy