Skip to Content

Do you lose weight on Wellbutrin SR?

Responses (3)

Anonymous 4 Jul 2016

I didn't lose weight on wellbutrin sr, but I didn't gain weight. But this is what happened to me: My weight somehow shifted, and I got thicker around the waist. When I quit the wellbutrin, my middle went back to normal. When I started back on the wellbutrin, my middle got bigger again.

Zanymom 4 Jul 2016

I wish I would lose weight on this med. I was told by my doctor it tends to make you hyper and more active and many lose weight on it. I was hoping that was the case because I'd love to lose 20 lbs. I have been doing crossfit for 3 weeks 2-3x per week and I have actually gained a few lbs but hard to tell if it's from meds or gaining muscle or water weight. I have been taking 300mg of Wellbutrin for a couple months now. I always mostly gain weight in my stomach area but I too also noticed that my pants fit tighter and not looser :( I didn't think it might be caused by the meds but after reading the other answer to this ? now I wonder. I'm not sure if this med is helping me either. Also I have noticed alot of headaches and cannot sleep at night well.

Anonymous 4 Jul 2016

I had gained 20 pounds while taking Lexapro. Then I was prescribed Buspar by my doctor for anxiety, which I had never taken before, although I had taken many different antidepressants and benzos in the past. I loved Buspar, although any people say it didn't work for them. I lost 23 pounds while taking it. After that, I started back on wellbutrin, and only gained back a couple of those unwanted pounds, but... I went back up a whole size in my jeans, because of the thickening around my waist from the wellbutrin. I am positive that is what caused it, because it happened to me in the past whenever I started back on my wellbutrin sr, although I didn't really gain weight on it. It just causes edema or "thickening" around the waist area. I had a friend that blew up like a balloon (went up 2 dress sizes) when she took Wellbutrin sr, and also had extreme anxiety while taking it. She takes effexor and loves it.

Anonymous 4 Jul 2016

*any people should be *many people. sorry!

Anonymous 24 Dec 2016

Update on my use of wellbutrin and weight loss/weight gain: I went back on it after this last post of mine. I unfortunately have gone off and on wellbutrin from time to time. Well, this last time when I went back on it, I monitored my weight gain/loss progress. Bottom line - sadly, as of my doctor visit 2 days ago, I have gained back much of the weight that I had lost while only being on buspar. Argh! Muffin top has mushroomed up. So has my blood pressure (I think from the extra weight). I guess you know what my New Year's Resolution will be - no more wellbutrin for me!!! -sad Gmc-

Auroraborealis 21 Dec 2016

Hi myfamily1010! I've always had the same problem of putting on weight on antidepressants, but a couple years ago I was put on a combination of Wellbutrin SR (300), Thymanax 25 at night and Topamax 150, and I lost weight FAST. I'm talking 22 lbs in a month and a half. I went from 125lbs to 103 just like that. My stomach hurt all the time though, it was horrible. At the time I thought it was the Topamax, but as I stopped taking both meds at the same time I never did find out.

I was just put back on Wellbutrin today, so I guess I'll find out if it was that and report back.

Drugs.com free discount card

Further Information

Search for questions

Still looking for answers? Try searching for what you seek or ask your own question.

Similar Questions