I have been on Zyban bupropion 150mg for 5 weeks now to treat recurring clinical depression and suffered horrendous side effects incl insomnia, extreme anxiety and irritability, nausea, extreme suicidal thoughts, forgetfulness - Its been hell! My depression is just as bad as before if not worse. I know the therapeutic dose is 300mg but am terrified of increasing dose in case side effects get even worse but have small hope that things could all get better in correct dose??? I could really do with some advice. My psychiatrist really doesn’t seem to know enough about this drug. Am in Uk so cant get brand Wellbutrin.