I have suffered with chronic back and leg pain for four years due to disc problems. I've had 2 surgeries, multiple injections, procedures and have tried Gabapentin and Cymbalta with very bad side effects. For the past three months I've been on Savella and it nearly made my pain disappear, I haven't felt that much relief in years, it was amazing. Recently I developed very bad cystitis which feels like a constant horrible urinary tract infection. My doctors determined it was from the Savella and have taken me off it, it has only been a little over a week and all my pain is coming back. I'm hoping to find something like Savella, but I don't know what is left to try... and am almost thinking the trade-off might be worth it.