I have been on Prednisone for over a month, this morning I woke sobbing with excruciating pain in my ankles and knees. Is this normal? I have read of other similar accounts. I am not tapering currently, I will be on 60 mg/day for a month, then taper down 10 mg per month for 5 for more months. Is there anything normal I can do to prevent this from happening? I am mentally prepared that the Prednisone is helping my UC/lung complications, but this pain was crazy. I took an Ativan and Oxycodone and it seems to have relieved the pain after an hour or so. Any guidance is truly appreciated.