I have been taking Mirtazapine 30mg for approx. 6 months now, after taking Dothiepin/Dosulepin 150mg for a number of years previously. One of the main side effects that I have had with changing medication is insomnia. Subsequently, my doctor has prescribed me with Zopiclone 7.5mg. I have never heard of these tablets before and therefore researched them on the internet and am now quite reluctant to take them. Does anyone know how they will react with my anti-depressants and also Dipenhydramine Hydrochloride, I have been self medicating with Nytol one a night for a couple of months now so this chemical will probably still be quite high in my system. Also I am due to go into hospital on Tuesday for an operation, will these chemicals have an adverse effect on the anaesthetic? Or am I better off post-poning the operation, which is also quite urgent as I am in a lot of pain the majority of the time?