She is now experiencing horrible leg cramps and severe restless leg syndrome. Her neurologist put her on 600 mg of gabapentin and not only does it do nothing it makes her really weak like a bowl of jello. We have called and the neurologist said we need to get her a primary care physician. We did this and she has an appointment here in about a week. What medications work best for severe cramps with restless leg syndrome so I can ask or request. My wife is completely diabled from her MS. She takes Tacfidera for her MS.She is also on 75 mg of effexor. Please help. She cries alot due to the cramps.She also has horrible pain in her back and shoulders. The neurologist said the gabapentin would help this also. Ridiculous. It does nothing.