She is now experiencing horrible leg cramps and severe restless leg syndrome. Her neurologist put her on 600 mg of gabapentin and not only does it do nothing it makes her really weak like a bowl of jello. We have called and the neurologist said we need to get her a primary care physician. We did this and she has an appointment here in about a week. What medications work best for severe cramps with restless leg syndrome so I can ask or request. My wife is completely diabled from her MS. She takes Tacfidera for her MS.She is also on 75 mg of effexor. Please help. She cries alot due to the cramps.She also has horrible pain in her back and shoulders. The neurologist said the gabapentin would help this also. Ridiculous. It does nothing.
Ok you are her advocate and you have to be firm with these Drs. The gabapentin or neurontin if it's not working then it's useless. Your wife needs a real pain medicine like oxycodone or hydrocodone to control the pain. She could highly benefit from a muscle relaxer like flexeril and an anti inflammatory medicine like plain old aspirin or there's medications like Celebrex. Mirapex, Requip or Neuropro are RLS specific medications. Restoral and Horizant work indirectly for RLS. If I were you I would start out with Mirapex, Flexeril, Oxycodone and an anti inflammatory like Celebrex.
I agree your wife needs stronger pain meds but also consider the side effects of these drugs as well. Requip may help with restless leg syndrome. Baclofen and /or Flexeril may help with pain and muscle cramping. Magnesium may also help with muscle cramping as well. These meds are less constipating and she might have less fogginess since they are not narcotics. However you should have vicodin or oxycontin for severe pain on hand as well just in case.
Keep in mind though magnesium may cause loose stools or diarrhea.
Your wife should try more than 75 mg of Effexor. I was severely depressed due to my severe medical problems. My doctor told me to increase it another 37.5 mg which helped me a lot. Not only does it help with depression, but it can moderate the pain some. Talk to her doctor about it. At the time, I told my doctor that absolutely no drug could help my depression because it was all situational. I was shocked at the difference that it made for me.
My best to your wife. I have spasticity and the pain in my right shin and hamstring is excruciating. I too cry. I am barely walking with a walker. After sitting or resting, my leg bends under and I can't stand at all. If I crawl a few seconds, it releases a bit for me to pull myself up.
I take a low dose of Tizanidine 3x a day, and aleve. I do not tolerate baclofen at all. I pray that there will be something soon to help us.
Finally, I can actually answer a question on this forum that directly relates to a resounding success that I have had. I've spent the last 7 years with trial and error drugs to try to relieve the debilitating leg pain from my MS. I, like your wife, spent many hours crying from the pain. Gabapentin definitely did not work. About 6 months ago, my neurologist put me on a generic form of Cymbalta called Duloxetine. She said that Cymbalta was originally prescribed as a depression treatment but they found that the positive side affect was that it relaxed muscles and helped with pain. We started with 30 mg and I could tell a difference, but still had to take pain meds. She told me we could go up to 90 mg, but I wanted to try 60 mg first. Within a couple of weeks I was taking pain meds only periodically and sleeping through the night.
After all the trial and error meds I have taken, I can only describe this as a miracle. I'm back to what my MS normal life is (with debilitating MS normal is an relative term). I'd be interested to hear how things go with your wife. Follow-ups on this website would be great.
- Gabapentin Information for Consumers
- Gabapentin Information for Healthcare Professionals (includes dosage details)
- Side Effects of Gabapentin (detailed)
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